Mitochondrial biogenesis is required for the anchorage-independent survival and propagation of stem-like cancer cells A De Luca, M Fiorillo, M Peiris-Pagès, B Ozsvari, DL Smith, ... Oncotarget 6 (17), 14777, 2015 | 261 | 2015 |
Graphene oxide selectively targets cancer stem cells, across multiple tumor types: implications for non-toxic cancer treatment, via “differentiation-based nano-therapy” M Fiorillo, AF Verre, M Iliut, M Peiris-Pagés, B Ozsvari, R Gandara, ... Oncotarget 6 (6), 3553, 2015 | 232 | 2015 |
Repurposing atovaquone: targeting mitochondrial complex III and OXPHOS to eradicate cancer stem cells M Fiorillo, R Lamb, HB Tanowitz, L Mutti, M Krstic-Demonacos, ... Oncotarget 7 (23), 34084, 2016 | 214 | 2016 |
Mitochondrial mass, a new metabolic biomarker for stem-like cancer cells: Understanding WNT/FGF-driven anabolic signaling R Lamb, G Bonuccelli, B Ozsvári, M Peiris-Pagès, M Fiorillo, DL Smith, ... Oncotarget 6 (31), 30453, 2015 | 133 | 2015 |
Bedaquiline, an FDA-approved antibiotic, inhibits mitochondrial function and potently blocks the proliferative expansion of stem-like cancer cells (CSCs) M Fiorillo, R Lamb, HB Tanowitz, AR Cappello, UE Martinez-Outschoorn, ... Aging (Albany NY) 8 (8), 1593, 2016 | 128 | 2016 |
Doxycycline down-regulates DNA-PK and radiosensitizes tumor initiating cells: Implications for more effective radiation therapy R Lamb, M Fiorillo, A Chadwick, B Ozsvari, KJ Reeves, DL Smith, ... Oncotarget 6 (16), 14005, 2015 | 115 | 2015 |
Mitochondrial “power” drives tamoxifen resistance: NQO1 and GCLC are new therapeutic targets in breast cancer M Fiorillo, F Sotgia, D Sisci, AR Cappello, MP Lisanti Oncotarget 8 (12), 20309, 2017 | 77 | 2017 |
Mitochondrial markers predict recurrence, metastasis and tamoxifen-resistance in breast cancer patients: Early detection of treatment failure with companion diagnostics F Sotgia, M Fiorillo, MP Lisanti Oncotarget 8 (40), 68730, 2017 | 76 | 2017 |
Hypocholesterolaemic activity of 3-hydroxy-3-methyl-glutaryl flavanones enriched fraction from bergamot fruit (Citrus bergamia):“In vivo” studies L Di Donna, D Iacopetta, AR Cappello, G Gallucci, E Martello, M Fiorillo, ... Journal of functional foods 7, 558-568, 2014 | 76 | 2014 |
Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs) M Fiorillo, F Tóth, F Sotgia, MP Lisanti Aging (Albany NY) 11 (8), 2202, 2019 | 73 | 2019 |
Bergamot (Citrus bergamia Risso) flavonoids and their potential benefits in human hyperlipidemia and atherosclerosis: an overview AR Cappello, V Dolce, D Iacopetta, M Martello, M Fiorillo, R Curcio, ... Mini reviews in medicinal chemistry 16 (8), 619-629, 2016 | 72 | 2016 |
Metabolic reprogramming of bone marrow stromal cells by leukemic extracellular vesicles in acute lymphoblastic leukemia SM Johnson, C Dempsey, A Chadwick, S Harrison, J Liu, Y Di, OJ McGinn, ... Blood, The Journal of the American Society of Hematology 128 (3), 453-456, 2016 | 69 | 2016 |
Bergamot natural products eradicate cancer stem cells (CSCs) by targeting mevalonate, Rho-GDI-signalling and mitochondrial metabolism M Fiorillo, M Peiris-Pagès, R Sanchez-Alvarez, L Bartella, L Di Donna, ... Biochimica Et Biophysica Acta (BBA)-Bioenergetics 1859 (9), 984-996, 2018 | 62 | 2018 |
“Energetic” cancer stem cells (e-CSCs): a new hyper-metabolic and proliferative tumor cell phenotype, driven by mitochondrial energy M Fiorillo, F Sotgia, MP Lisanti Frontiers in oncology 8, 677, 2019 | 59 | 2019 |
A mitochondrial based oncology platform for targeting cancer stem cells (CSCs): MITO-ONC-RX F Sotgia, B Ozsvari, M Fiorillo, EM De Francesco, G Bonuccelli, MP Lisanti Cell Cycle 17 (17), 2091-2100, 2018 | 54 | 2018 |
High ATP production fuels cancer drug resistance and metastasis: implications for mitochondrial ATP depletion therapy M Fiorillo, B Ozsvari, F Sotgia, MP Lisanti Frontiers in oncology 11, 740720, 2021 | 53 | 2021 |
Estrogen related receptor α (ERRα) a promising target for the therapy of adrenocortical carcinoma (ACC) I Casaburi, P Avena, A De Luca, A Chimento, R Sirianni, R Malivindi, ... Oncotarget 6 (28), 25135, 2015 | 48 | 2015 |
Mass Spectrometry-Based Proteomic Approach in Oenococcus oeni Enological Starter A Napoli, D Aiello, G Aiello, MS Cappello, L Di Donna, F Mazzotti, ... Journal of Proteome Research 13 (6), 2856-2866, 2014 | 48 | 2014 |
Mitoriboscins: Mitochondrial-based therapeutics targeting cancer stem cells (CSCs), bacteria and pathogenic yeast B Ozsvari, M Fiorillo, G Bonuccelli, AR Cappello, L Frattaruolo, F Sotgia, ... Oncotarget 8 (40), 67457, 2017 | 46 | 2017 |
Cholesterol and mevalonate: two metabolites involved in breast cancer progression and drug resistance through the ERRα pathway M Brindisi, M Fiorillo, L Frattaruolo, F Sotgia, MP Lisanti, AR Cappello Cells 9 (8), 1819, 2020 | 43 | 2020 |