The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer AK Najumudeen, F Ceteci, SK Fey, G Hamm, RT Steven, H Hall, ... Nature genetics 53 (1), 16-26, 2021 | 150 | 2021 |
Biological misinterpretation of transcriptional signatures in tumor samples can unknowingly undermine mechanistic understanding and faithful alignment with preclinical data NC Fisher, RM Byrne, H Leslie, C Wood, A Legrini, AJ Cameron, ... Clinical Cancer Research 28 (18), 4056-4069, 2022 | 19 | 2022 |
In-depth clinical and biological exploration of DNA damage immune response as a biomarker for oxaliplatin use in colorectal cancer SB Malla, DJ Fisher, E Domingo, A Blake, S Hassanieh, KL Redmond, ... Clinical Cancer Research 27 (1), 288-300, 2021 | 19 | 2021 |
MmCMS: mouse models’ consensus molecular subtypes of colorectal cancer R Amirkhah, K Gilroy, SB Malla, TRM Lannagan, RM Byrne, NC Fisher, ... British Journal of Cancer 128 (7), 1333-1343, 2023 | 12 | 2023 |
Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer SB Malla, RM Byrne, MW Lafarge, SM Corry, NC Fisher, PK Tsantoulis, ... Nature Genetics 56 (3), 458-472, 2024 | 9 | 2024 |
Molecular Subtyping Resource: a user-friendly tool for rapid biological discovery from transcriptional data B Ahmaderaghi, R Amirkhah, J Jackson, TRM Lannagan, K Gilroy, ... Disease Models & Mechanisms 15 (3), dmm049257, 2022 | 7 | 2022 |
Activation of innate-adaptive immune machinery by poly (I: C) exposes a therapeutic vulnerability to prevent relapse in stroma-rich colon cancer SM Corry, AMB McCorry, TRM Lannagan, NA Leonard, NC Fisher, ... Gut 71 (12), 2502-2517, 2022 | 6 | 2022 |
Author Correction: Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer SB Malla, RM Byrne, MW Lafarge, SM Corry, NC Fisher, PK Tsantoulis, ... Nature Genetics, 1-1, 2024 | 1 | 2024 |
Pathway level subtyping identifies a slow-cycling and transcriptionally lethargic biological phenotype associated with poor clinical outcomes in colon cancer independent of … SB Malla, RM Byrne, M Lafarge, SM Corry, NC Fisher, P Tsantoulis, ... | 1 | 2024 |
PLAC8-mediated activation of NOX4 signalling restores angiogenic function of endothelial colony-forming cells in experimental hypoxia SH Pun, KM O’Neill, KS Edgar, EK Gill, A Moez, H Naderi-Meshkin, ... Cells 12 (18), 2220, 2023 | 1 | 2023 |
Library size can undermine accurate molecular and phenotypic subtyping in spatial transcriptomics data. NC Fisher, SB Malla, N Jamieson, PD Dunne bioRxiv, 2024.07. 07.602370, 2024 | | 2024 |
Evaluation of Gene Set Enrichment Analysis (GSEA) tools highlights the value of single sample approaches over pairwise for robust biological discovery. C Bull, RM Byrne, NC Fisher, SM Corry, R Amirkhah, J Edwards, L Hillson, ... bioRxiv, 2024.03. 15.585228, 2024 | | 2024 |
PLAC8-Mediated Activation of NOX4 Signalling Restores Angiogenic Function of Endothelial Colony-Forming Cells in Experimental Hypoxia. Cells 2023, 12, 2220 SH Pun, KM O’Neill, KS Edgar, EK Gill, A Moez, H Naderi-Meshkin, ... | | 2023 |
Activation of NOX4 NADPH oxidase signalling restores angiogenic function of cord blood endothelial colony-forming cells in hypoxia SH Pun, K O'Neill, H Naderi-Meshkin, S Malla, P Dunne, C Watson, ... Journal of Molecular and Cellular Cardiology 173, S56, 2022 | | 2022 |
Capacity Development in a Participatory Adaptive Programme: the Case of the Clarissa Consortium M Widmer, M Apgar, J Afroze, S Malla, J Healey, S Constant IDS, 2022 | | 2022 |
Ontology-led molecular classification of colorectal cancer uncovers distinct tumour subtypes with therapeutic and clinical relevance S Malla Queen's University Belfast, 2022 | | 2022 |
The Molecular Subtyping Resource (MouSR): a user-friendly tool for rapid biological discovery from human or mouse transcriptional data B Ahmaderaghi, R Amirkhah, J Jackson, TRM Lannagan, K Gilroy, ... bioRxiv, 2021.08. 12.456127, 2021 | | 2021 |
Exploration of molecular signalling underpinning the DNA Damage Response Deficiency (DDRD) assay in Colorectal Cancer; Data from the S: CORT consortium (Stratification in … S Malla, K Redmond, A Blake, E Domingo, S Richman, M Youdell, ... BRITISH JOURNAL OF CANCER 121, 3-3, 2019 | | 2019 |