| Structure of the polycystic kidney disease TRP channel Polycystin-2 (PC2) M Grieben, ACW Pike, CA Shintre, E Venturi, S El-Ajouz, A Tessitore, ... Nature structural & molecular biology 24 (2), 114-122, 2017 | 190 | 2017 |
| Purification of an insect defensin from the mosquito, Aedes aegypti R Chalk, H Townson, S Natori, H Desmond, PJ Ham Insect biochemistry and molecular biology 24 (4), 403-410, 1994 | 115 | 1994 |
| Hierarchical high-throughput SNP genotyping of the human Y chromosome using MALDI-TOF mass spectrometry S Paracchini, B Arredi, R Chalk, C Tyler-Smith Nucleic Acids Research 30 (6), e27-e27, 2002 | 96 | 2002 |
| Structural complexity in the KCTD family of Cullin3-dependent E3 ubiquitin ligases DM Pinkas, CE Sanvitale, JC Bufton, FJ Sorrell, N Solcan, R Chalk, ... Biochemical Journal 474 (22), 3747-3761, 2017 | 81 | 2017 |
| Tricyclic cell-penetrating peptides for efficient delivery of functional antibodies into cancer cells O Tietz, F Cortezon-Tamarit, R Chalk, S Able, KA Vallis Nature Chemistry 14 (3), 284-293, 2022 | 75 | 2022 |
| Brugia pahangi: the effects of cecropins on microfilariae in vitro and in Aedes aegypti R Chalk, H Townson, PJ Ham Experimental parasitology 80 (3), 401-406, 1995 | 70 | 1995 |
| Structures of DPAGT1 explain glycosylation disease mechanisms and advance TB antibiotic design YY Dong, H Wang, ACW Pike, SA Cochrane, S Hamedzadeh, ... Cell 175 (4), 1045-1058. e16, 2018 | 66 | 2018 |
| Structural basis for the regulation of human 5, 10-methylenetetrahydrofolate reductase by phosphorylation and S-adenosylmethionine inhibition DS Froese, J Kopec, E Rembeza, GA Bezerra, AE Oberholzer, ... Nature communications 9 (1), 2261, 2018 | 65 | 2018 |
| Molecular basis of classic galactosemia from the structure of human galactose 1-phosphate uridylyltransferase TJ McCorvie, J Kopec, AL Pey, F Fitzpatrick, D Patel, R Chalk, L Shrestha, ... Human Molecular Genetics 25 (11), 2234-2244, 2016 | 62 | 2016 |
| Trityl tags for encoding in combinatorial synthesis MS Shchepinov, R Chalk, EM Southern Tetrahedron 56 (17), 2713-2724, 2000 | 51 | 2000 |
| Full sequence and characterization of two insect defensins: immune peptides from the mosquito Aedes aegypti R Chalk, CMR Albuquerque, PJ Ham, H Townson Proceedings of the Royal Society of London. Series B: Biological Sciences …, 1995 | 51 | 1995 |
| Structural insights into the MMACHC-MMADHC protein complex involved in vitamin B12 trafficking DS Froese, J Kopec, F Fitzpatrick, M Schuller, TJ McCorvie, R Chalk, ... Journal of Biological Chemistry 290 (49), 29167-29177, 2015 | 46 | 2015 |
| Quantitative analysis of MRP‐8 in gingival crevicular fluid in periodontal health and disease using microbore HPLC FT Lundy, R Chalk, PJ Lamey, C Shaw, GJ Linden Journal of clinical periodontology 28 (12), 1172-1177, 2001 | 41 | 2001 |
| Trityl mass-tags for encoding in combinatorial oligonucleotide synthesis MS Shchepinov, R Chalk, EM Southern Nucleic acids symposium series 42 (1), 107-108, 1999 | 41 | 1999 |
| Glibenclamide reverses cardiovascular abnormalities of Cantu syndrome driven by KATP channel overactivity C McClenaghan, Y Huang, Z Yan, TM Harter, CM Halabi, R Chalk, ... The Journal of clinical investigation 130 (3), 1116-1121, 2020 | 40 | 2020 |
| Tryptophan-mediated interactions between tristetraprolin and the CNOT9 subunit are required for CCR4-NOT deadenylase complex recruitment D Bulbrook, H Brazier, P Mahajan, M Kliszczak, O Fedorov, FP Marchese, ... Journal of molecular biology 430 (5), 722-736, 2018 | 40 | 2018 |
| Identification of MRP‐8 (calgranulin A) as a major responsive protein in chronic periodontitis FT Lundy, R Chalk, PJ Lamey, C Shaw, GJ Linden The Journal of Pathology: A Journal of the Pathological Society of Great …, 2000 | 40 | 2000 |
| The spectrum of endogenous human chromogranin A‐derived peptides identified using a modified proteomic strategy DF Orr, T Chen, AH Johnsen, R Chalk, KD Buchanan, JM Sloan, P Rao, ... Proteomics 2 (11), 1586-1600, 2002 | 34 | 2002 |
| High-performance liquid chromatography separation and intact mass analysis of detergent-solubilized integral membrane proteins G Berridge, R Chalk, N D’Avanzo, L Dong, D Doyle, JI Kim, X Xia, ... Analytical biochemistry 410 (2), 272-280, 2011 | 31 | 2011 |
| Serum indoleamine 2, 3-dioxygenase activity is associated with reduced immunogenicity following vaccination with MVA85A R Tanner, K Kakalacheva, E Miller, AA Pathan, R Chalk, CR Sander, ... BMC infectious diseases 14, 1-10, 2014 | 24 | 2014 |
