| ChAMP: 450k chip analysis methylation pipeline TJ Morris, LM Butcher, A Feber, AE Teschendorff, AR Chakravarthy, ... Bioinformatics 30 (3), 428-430, 2014 | 898 | 2014 |
| Sensitive tumour detection and classification using plasma cell-free DNA methylomes SY Shen, R Singhania, G Fehringer, A Chakravarthy, MHA Roehrl, ... Nature 563 (7732), 579-583, 2018 | 725 | 2018 |
| LSD1 ablation stimulates anti-tumor immunity and enables checkpoint blockade W Sheng, MW LaFleur, TH Nguyen, S Chen, A Chakravarthy, JR Conway, ... Cell 174 (3), 549-563. e19, 2018 | 558 | 2018 |
| TGF-β-associated extracellular matrix genes link cancer-associated fibroblasts to immune evasion and immunotherapy failure A Chakravarthy, L Khan, NP Bensler, P Bose, DD De Carvalho Nature communications 9 (1), 4692, 2018 | 470 | 2018 |
| Epigenetic therapy in immune-oncology PA Jones, H Ohtani, A Chakravarthy, DD De Carvalho Nature Reviews Cancer 19 (3), 151-161, 2019 | 427 | 2019 |
| APOBEC-mediated cytosine deamination links PIK3CA helical domain mutations to human papillomavirus-driven tumor development S Henderson, A Chakravarthy, X Su, C Boshoff, TR Fenton Cell reports 7 (6), 1833-1841, 2014 | 379 | 2014 |
| Pan-cancer deconvolution of tumour composition using DNA methylation A Chakravarthy, A Furness, K Joshi, E Ghorani, K Ford, MJ Ward, EV King, ... Nature communications 9 (1), 3220, 2018 | 258 | 2018 |
| A clinically applicable integrative molecular classification of meningiomas F Nassiri, J Liu, V Patil, Y Mamatjan, JZ Wang, R Hugh-White, AM Macklin, ... Nature 597 (7874), 119-125, 2021 | 244 | 2021 |
| Detection of renal cell carcinoma using plasma and urine cell-free DNA methylomes PV Nuzzo, JE Berchuck, K Korthauer, S Spisak, AH Nassar, S Abou Alaiwi, ... Nature medicine 26 (7), 1041-1043, 2020 | 221 | 2020 |
| The TRAIL-induced cancer secretome promotes a tumor-supportive immune microenvironment via CCR2 T Hartwig, A Montinaro, S von Karstedt, A Sevko, S Surinova, ... Molecular cell 65 (4), 730-742. e5, 2017 | 218 | 2017 |
| NOX4 inhibition potentiates immunotherapy by overcoming cancer-associated fibroblast-mediated CD8 T-cell exclusion from tumors K Ford, CJ Hanley, M Mellone, C Szyndralewiez, F Heitz, P Wiesel, ... Cancer research 80 (9), 1846-1860, 2020 | 217 | 2020 |
| Detection and discrimination of intracranial tumors using plasma cell-free DNA methylomes F Nassiri, A Chakravarthy, S Feng, SY Shen, R Nejad, JA Zuccato, ... Nature medicine 26 (7), 1044-1047, 2020 | 215 | 2020 |
| Epigenetic therapy induces transcription of inverted SINEs and ADAR1 dependency P Mehdipour, SA Marhon, I Ettayebi, A Chakravarthy, A Hosseini, Y Wang, ... Nature 588 (7836), 169-173, 2020 | 177 | 2020 |
| Apoptotic cell–induced AhR activity is required for immunological tolerance and suppression of systemic lupus erythematosus in mice and humans R Shinde, K Hezaveh, MJ Halaby, A Kloetgen, A Chakravarthy, ... Nature immunology 19 (6), 571-582, 2018 | 155 | 2018 |
| Identification and functional validation of HPV-mediated hypermethylation in head and neck squamous cell carcinoma M Lechner, T Fenton, J West, G Wilson, A Feber, S Henderson, C Thirlwell, ... Genome medicine 5, 1-16, 2013 | 146 | 2013 |
| Human papillomavirus drives tumor development throughout the head and neck: improved prognosis is associated with an immune response largely restricted to the oropharynx A Chakravarthy, S Henderson, SM Thirdborough, CH Ottensmeier, X Su, ... Journal of Clinical Oncology 34 (34), 4132-4141, 2016 | 131 | 2016 |
| GCN2 drives macrophage and MDSC function and immunosuppression in the tumor microenvironment MJ Halaby, K Hezaveh, S Lamorte, MT Ciudad, A Kloetgen, BL MacLeod, ... Science immunology 4 (42), eaax8189, 2019 | 105 | 2019 |
| DNA hypomethylating agents increase activation and cytolytic activity of CD8+ T cells HL Yau, E Bell, I Ettayebi, FC de Almeida, GM Boukhaled, SY Shen, ... Molecular cell 81 (7), 1469-1483. e8, 2021 | 66 | 2021 |
| Frequent HPV-independent p16/INK4A overexpression in head and neck cancer M Lechner, AR Chakravarthy, V Walter, L Masterson, A Feber, A Jay, ... Oral Oncology 83, 32-37, 2018 | 56 | 2018 |
| CSN1 Somatic Mutations in Penile Squamous Cell Carcinoma A Feber, DC Worth, A Chakravarthy, P de Winter, K Shah, M Arya, ... Cancer research 76 (16), 4720-4727, 2016 | 54 | 2016 |
