| Engineering proteins for thermostability through rigidifying flexible sites H Yu, H Huang Biotechnology Advances 32 (2), 308-315, 2014 | 243 | 2014 |
| Two strategies to engineer flexible loops for improved enzyme thermostability H Yu, Y Yan, C Zhang, P Dalby Scientific Report 7, 2017 | 173 | 2017 |
| The role of proline substitutions within flexible regions on thermostability of luciferase H Yu, Y Zhao, C Guo, Y Gan, H Huang Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1854 (1), 65-72, 2015 | 98 | 2015 |
| Coupled molecular dynamics mediate long- and short-range epistasis between mutations that affect stability and aggregation kinetics H Yu, P Dalby Proceedings of the National Academy of Sciences, 2018 | 78 | 2018 |
| Exploiting correlated molecular-dynamics networks to counteract enzyme activity-stability trade-off H Yu, P Dalby Proceedings of the National Academy of Sciences, 2018 | 70 | 2018 |
| Hot spots-making directed evolution easier H Yu, S Ma, Y Li, PA Dalby Biotechnology Advances 56, 107926, 2022 | 46 | 2022 |
| Directed Evolution of l-Threonine Aldolase for the Diastereoselective Synthesis of β-Hydroxy-α-amino Acids W Zheng, H Yu, S Fang, K Chen, Z Wang, X Cheng, G Xu, L Yang, J Wu ACS Catalysis 11 (6), 3198-3205, 2021 | 38 | 2021 |
| Computational-design to reduce conformational flexibility and aggregation rates of an antibody Fab fragment C Zhang, M Samad, H Yu, N Chakroun, D Hilton, P Dalby Molecular pharmaceutics, 2018 | 32 | 2018 |
| Rational design of enzyme activity and enantioselectivity Z Song, Q Zhang, W Wu, Z Pu, H Yu Frontiers in Bioengineering and Biotechnology 11, 1129149, 2023 | 29 | 2023 |
| Multi-level Protein Structure Pre-training via Prompt Learning Z Wang, Q Zhang, HU Shuang-Wei, H Yu, X Jin, Z Gong, H Chen The Eleventh International Conference on Learning Representations, 2023 | 26 | 2023 |
| A beginner's guide to molecular dynamics simulations and the identification of cross-correlation networks for enzyme engineering H Yu, PA Dalby Methods in enzymology 643, 15-49, 2020 | 26 | 2020 |
| Enhanced trypsin thermostability in Pichia pastoris through truncating the flexible region L Liu, H Yu, K Du, Z Wang, Y Gan, H Huang Microbial cell factories 17, 1-10, 2018 | 25 | 2018 |
| Engineering transketolase to accept both unnatural donor and acceptor substrates and produce α‐hydroxyketones H Yu, RIH López, D Steadman, D Méndez‐Sánchez, S Higson, ... The FEBS Journal, 2019 | 21 | 2019 |
| Mutability‐Landscape‐Guided Engineering of l‐Threonine Aldolase Revealing the Prelog Rule in Mediating Diastereoselectivity of C−C Bond Formation W Zheng, Z Pu, L Xiao, G Xu, L Yang, H Yu, J Wu Angewandte Chemie 135 (2), e202213855, 2023 | 19 | 2023 |
| Computational design of highly stable and soluble alcohol dehydrogenase for NADPH regeneration J Xu, H Zhou, H Yu, T Deng, Z Wang, H Zhang, J Wu, L Yang Bioresources and Bioprocessing 8, 1-13, 2021 | 19 | 2021 |
| Enhancing thermostability of lipase from Pseudomonas alcaligenes for producing l-menthol by the CREATE strategy Z Yu, H Yu, J Xu, Z Wang, Z Wang, T Kang, K Chen, Z Pu, J Wu, L Yang, ... Catalysis Science & Technology 12 (8), 2531-2541, 2022 | 18 | 2022 |
| Sequence and Structure-Guided Engineering of Urethanase from Agrobacterium tumefaciens d3 for Improved Catalytic Activity X Yao, T Kang, Z Pu, T Zhang, J Lin, L Yang, H Yu, M Wu Journal of Agricultural and Food Chemistry 70 (23), 7267-7278, 2022 | 16 | 2022 |
| Computational Redesign of the Substrate Binding Pocket of Glutamate Dehydrogenase for Efficient Synthesis of Noncanonical l-Amino Acids Z Wang, H Zhou, H Yu, Z Pu, J Xu, H Zhang, J Wu, L Yang ACS Catalysis 12 (21), 13619-13629, 2022 | 12 | 2022 |
| A novel strategy for thermostability improvement of trypsin based on N-glycosylation within the Ω-loop region C Guo, Y Liu, H Yu, K Du, Y Gan, H Huang Journal of Microbiology and Biotechnology 26 (7), 1163-1172, 2016 | 11 | 2016 |
| Engineering of flavonoid 3′-O-methyltransferase for improved biosynthesis of chrysoeriol in Escherichia coli X Wu, M Yuwen, Z Pu, Z Zhao, H Yu, J Zha Applied Microbiology and Biotechnology 107 (5), 1663-1672, 2023 | 9 | 2023 |
Paul DalbyUniversity College London在 ucl.ac.uk 的电子邮件经过验证
Paul DalbyUniversity College London在 ucl.ac.uk 的电子邮件经过验证