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Klaus H. Metzeler
Klaus H. Metzeler
University Hospital Leipzig, Germany
在 klaus-metzeler.de 的电子邮件经过验证 - 首页
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引用次数
引用次数
年份
Stem cell gene expression programs influence clinical outcome in human leukemia
K Eppert, K Takenaka, ER Lechman, L Waldron, B Nilsson, P Van Galen, ...
Nature medicine 17 (9), 1086-1093, 2011
11682011
IDH1 and IDH2 Gene Mutations Identify Novel Molecular Subsets Within De Novo Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia …
G Marcucci, K Maharry, YZ Wu, MD Radmacher, K Mrózek, D Margeson, ...
Journal of clinical oncology 28 (14), 2348-2355, 2010
9742010
A 17-gene stemness score for rapid determination of risk in acute leukaemia
SWK Ng, A Mitchell, JA Kennedy, WC Chen, J McLeod, N Ibrahimova, ...
Nature 540 (7633), 433-437, 2016
7822016
Spectrum and prognostic relevance of driver gene mutations in acute myeloid leukemia
KH Metzeler, T Herold, M Rothenberg-Thurley, S Amler, MC Sauerland, ...
Blood, The Journal of the American Society of Hematology 128 (5), 686-698, 2016
5802016
Prognostic significance of the European LeukemiaNet standardized system for reporting cytogenetic and molecular alterations in adults with acute myeloid leukemia
K Mrózek, G Marcucci, D Nicolet, KS Maharry, H Becker, SP Whitman, ...
Journal of clinical oncology 30 (36), 4515-4523, 2012
5182012
An 86-probe-set gene-expression signature predicts survival in cytogenetically normal acute myeloid leukemia
KH Metzeler, M Hummel, CD Bloomfield, K Spiekermann, J Braess, ...
Blood 112 (10), 4193-4201, 2008
4542008
TET2 Mutations Improve the New European LeukemiaNet Risk Classification of Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study
KH Metzeler, K Maharry, MD Radmacher, K Mrózek, D Margeson, ...
Journal of clinical oncology 29 (10), 1373-1381, 2011
4362011
Acute Myeloid Leukemia With Biallelic CEBPA Gene Mutations and Normal Karyotype Represents a Distinct Genetic Entity Associated With a Favorable Clinical …
A Dufour, F Schneider, KH Metzeler, E Hoster, S Schneider, E Zellmeier, ...
Journal of clinical oncology 28 (4), 570-577, 2010
3802010
ASXL1 mutations identify a high-risk subgroup of older patients with primary cytogenetically normal AML within the ELN Favorable genetic category
KH Metzeler, H Becker, K Maharry, MD Radmacher, J Kohlschmidt, ...
Blood, The Journal of the American Society of Hematology 118 (26), 6920-6929, 2011
3512011
Age-Related Prognostic Impact of Different Types of DNMT3A Mutations in Adults With Primary Cytogenetically Normal Acute Myeloid Leukemia
G Marcucci, KH Metzeler, S Schwind, H Becker, K Maharry, K Mrózek, ...
Journal of clinical oncology 30 (7), 742-750, 2012
3472012
RUNX1 Mutations Are Associated With Poor Outcome in Younger and Older Patients With Cytogenetically Normal Acute Myeloid Leukemia and With Distinct Gene …
JH Mendler, K Maharry, MD Radmacher, K Mrózek, H Becker, ...
Journal of clinical oncology 30 (25), 3109-3118, 2012
3402012
Coexpression profile of leukemic stem cell markers for combinatorial targeted therapy in AML
S Haubner, F Perna, T Köhnke, C Schmidt, S Berman, C Augsberger, ...
Leukemia 33 (1), 64-74, 2019
2672019
FLT3 internal tandem duplication associates with adverse outcome and gene- and microRNA-expression signatures in patients 60 years of age or older with …
SP Whitman, K Maharry, MD Radmacher, H Becker, K Mrózek, ...
Blood, The Journal of the American Society of Hematology 116 (18), 3622-3626, 2010
2672010
Blockade of the PD-1/PD-L1 axis augments lysis of AML cells by the CD33/CD3 BiTE antibody construct AMG 330: reversing a T-cell-induced immune escape mechanism
C Krupka, P Kufer, R Kischel, G Zugmaier, FS Lichtenegger, T Köhnke, ...
Leukemia 30 (2), 484-491, 2016
2632016
DNMT3A mutations and response to the hypomethylating agent decitabine in acute myeloid leukemia
KH Metzeler, A Walker, S Geyer, R Garzon, RB Klisovic, CD Bloomfield, ...
Leukemia 26 (5), 1106-1107, 2012
2432012
Prognostic Significance of Expression of a Single MicroRNA, miR-181a, in Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study
S Schwind, K Maharry, MD Radmacher, K Mrózek, KB Holland, ...
Journal of clinical oncology 28 (36), 5257-5264, 2010
2312010
CD33 target validation and sustained depletion of AML blasts in long-term cultures by the bispecific T-cell–engaging antibody AMG 330
C Krupka, P Kufer, R Kischel, G Zugmaier, J Bögeholz, T Köhnke, ...
Blood, The Journal of the American Society of Hematology 123 (3), 356-365, 2014
2292014
Clinical Role of microRNAs in Cytogenetically Normal Acute Myeloid Leukemia: miR-155 Upregulation Independently Identifies High-Risk Patients
G Marcucci, KS Maharry, KH Metzeler, S Volinia, YZ Wu, K Mrózek, ...
Journal of clinical oncology 31 (17), 2086-2093, 2013
2152013
Validation and refinement of the revised 2017 European LeukemiaNet genetic risk stratification of acute myeloid leukemia
T Herold, M Rothenberg-Thurley, VV Grunwald, H Janke, D Goerlich, ...
Leukemia 34 (12), 3161-3172, 2020
1962020
Adults with Philadelphia chromosome–like acute lymphoblastic leukemia frequently have IGH-CRLF2 and JAK2 mutations, persistence of minimal residual disease and poor prognosis
T Herold, S Schneider, KH Metzeler, M Neumann, L Hartmann, ...
haematologica 102 (1), 130, 2017
1742017
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