Synthesis of a Targeted Library of Heparan Sulfate Hexa‐to Dodecasaccharides as Inhibitors of β‐Secretase: Potential Therapeutics for Alzheimer’s Disease R Schwörer, OV Zubkova, JE Turnbull, PC Tyler Chemistry–A European Journal 19 (21), 6817-6823, 2013 | 116 | 2013 |
Efficient sialyltransferase inhibitors based on glycosides of N-acetylglucosamine R Schwörer, RR Schmidt Journal of the American Chemical Society 124 (8), 1632-1637, 2002 | 92 | 2002 |
Stereoselective synthesis of phosphoramidate α (2-6) sialyltransferase transition-state analogue inhibitors D Skropeta, R Schwörer, RR Schmidt Bioorganic & medicinal chemistry letters 13 (19), 3351-3354, 2003 | 56 | 2003 |
Shotgun ion mobility mass spectrometry sequencing of heparan sulfate saccharides RL Miller, SE Guimond, R Schwörer, OV Zubkova, PC Tyler, Y Xu, J Liu, ... Nature communications 11 (1), 1481, 2020 | 52 | 2020 |
Asymmetric synthesis and affinity of potent sialyltransferase inhibitors based on transition-state analogues D Skropeta, R Schwörer, T Haag, RR Schmidt Glycoconjugate journal 21, 205-219, 2004 | 48 | 2004 |
Base‐ and Sugar‐Modified Cytidine Monophosphate N‐Acetylneuraminic Acid (CMP‐Neu5Ac) Analogues ‐ Synthesis and Studies with α(2‐6)‐Sialyltransferase … G Dufner, R Schwörer, B Müller, RR Schmidt European Journal of Organic Chemistry 2000 (8), 1467-1482, 2000 | 43 | 2000 |
Unique regulation of the active site of the serine esterase S-formylglutathione hydrolase I Cummins, K McAuley, A Fordham-Skelton, R Schwoerer, PG Steel, ... Journal of molecular biology 359 (2), 422-432, 2006 | 42 | 2006 |
Sialyltransferase inhibitors KH Jung, R Schwörer, RR Schmidt Trends in Glycoscience and Glycotechnology 15 (85), 275-289, 2003 | 25 | 2003 |
Composition, sequencing and ion mobility mass spectrometry of heparan sulfate-like octasaccharide isomers differing in glucuronic and iduronic acid content RL Miller, W Wei, R Schwörer, OV Zubkova, PC Tyler, JE Turnbull, ... European Journal of Mass Spectrometry 21 (3), 245-254, 2015 | 24 | 2015 |
Using automated glycan assembly (AGA) for the practical synthesis of heparan sulfate oligosaccharide precursors D Budhadev, K Saxby, J Walton, G Davies, PC Tyler, R Schwörer, ... Organic & biomolecular chemistry 17 (7), 1817-1821, 2019 | 23 | 2019 |
Me2Si (C5Me4) 2Cr: Synthesis and Crystal Structure of a Ligand-Free a nsa-Chromocene F Schaper, O Wrobel, R Schwörer, HH Brintzinger Organometallics 23 (14), 3552-3555, 2004 | 22 | 2004 |
Lipo-Chitin Oligosaccharides, Plant Symbiosis Signalling Molecules That Modulate Mammalian Angiogenesis In Vitro MA Djordjevic, A Bezos, Susanti, L Marmuse, H Driguez, E Samain, ... PLoS One 9 (12), e112635, 2014 | 21 | 2014 |
N‐Phenyltrifluoromethanesulfonimide WE Zeller, R Schwörer Encyclopedia of Reagents for Organic Synthesis, 2001 | 8 | 2001 |
Intracellular complexities of acquiring a new enzymatic function revealed by mass-randomisation of active-site residues KR Hall, KJ Robins, EM Williams, MH Rich, MJ Calcott, JN Copp, RF Little, ... Elife 9, e59081, 2020 | 7 | 2020 |
Comparison of disaccharide donors for heparan sulfate synthesis: uronic acids vs. their pyranose equivalents DJ Sheppard, SA Cameron, PC Tyler, R Schwörer Organic & biomolecular chemistry 18 (25), 4728-4733, 2020 | 4 | 2020 |
Translationally related nearly identical molecules: 4-methoxyphenyl 4-O-[6-O-acetyl-2-azido-3-O-benzyl-2-deoxy-4-O-(fluoren-9-ylmethoxycarbonyl)-α-D-glucopyranosyl]-2-O-benzoyl … GJ Gainsford, R Schwörer, PC Tyler Acta Crystallographica Section C: Crystal Structure Communications 69 (6 …, 2013 | 3 | 2013 |
Crystal packing in three related disaccharides: precursors to heparan sulfate oligosaccharides GJ Gainsford, R Schwörer, PC Tyler, OV Zubkova Acta Crystallographica Section E: Crystallographic Communications 71 (6 …, 2015 | 2 | 2015 |
2-(Acetoxymethyl) benzoic acid GJ Gainsford, R Schwörer Acta Crystallographica Section E: Structure Reports Online 69 (2), o259-o259, 2013 | 2 | 2013 |
Rational synthesis of a heparan sulfate saccharide that promotes the activity of BMP2 KJ Shaffer, RAA Smith, AM Daines, X Luo, X Lu, TC Tan, BQ Le, ... Carbohydrate Polymers 333, 121979, 2024 | 1 | 2024 |
A giant leap in sequence space reveals the intracellular complexities of evolving a new function KR Hall, KJ Robins, MH Rich, MJ Calcott, JN Copp, EM Williams, RF Little, ... BioRxiv, 2020.05. 27.118489, 2020 | 1 | 2020 |