Small molecular antibacterial peptoid mimics: the simpler the better! C Ghosh, GB Manjunath, P Akkapeddi, V Yarlagadda, J Hoque, ... Journal of medicinal chemistry 57 (4), 1428-1436, 2014 | 205 | 2014 |
Cleavable cationic antibacterial amphiphiles: synthesis, mechanism of action, and cytotoxicities J Hoque, P Akkapeddi, V Yarlagadda, DSSM Uppu, P Kumar, J Haldar Langmuir 28 (33), 12225-12234, 2012 | 200 | 2012 |
Construction of homogeneous antibody–drug conjugates using site-selective protein chemistry P Akkapeddi, SA Azizi, AM Freedy, PMSD Cal, PMP Gois, GJL Bernardes Chemical Science 7 (5), 2954-2963, 2016 | 177 | 2016 |
Membrane active vancomycin analogues: a strategy to combat bacterial resistance V Yarlagadda, P Akkapeddi, GB Manjunath, J Haldar Journal of medicinal chemistry 57 (11), 4558-4568, 2014 | 168 | 2014 |
Broad spectrum antibacterial and antifungal polymeric paint materials: Synthesis, structure–activity relationship, and membrane-active mode of action J Hoque, P Akkapeddi, V Yadav, GB Manjunath, DSSM Uppu, MM Konai, ... ACS applied materials & interfaces 7 (3), 1804-1815, 2015 | 153 | 2015 |
Polymers with tunable side-chain amphiphilicity as non-hemolytic antibacterial agents DSSM Uppu, P Akkapeddi, GB Manjunath, V Yarlagadda, J Hoque, ... Chemical communications 49 (82), 9389-9391, 2013 | 123 | 2013 |
Chemoselective installation of amine bonds on proteins through aza-Michael ligation AM Freedy, MJ Matos, O Boutureira, F Corzana, A Guerreiro, P Akkapeddi, ... Journal of the American Chemical Society 139 (50), 18365-18375, 2017 | 102 | 2017 |
IL-7R-mediated signaling in T-cell acute lymphoblastic leukemia: An update ML Oliveira, P Akkapeddi, D Ribeiro, A Melão, JT Barata Advances in biological regulation 71, 88-96, 2019 | 94 | 2019 |
Glycopeptide antibiotic to overcome the intrinsic resistance of Gram-negative bacteria V Yarlagadda, GB Manjunath, P Sarkar, P Akkapeddi, K Paramanandham, ... ACS infectious diseases 2 (2), 132-139, 2016 | 94 | 2016 |
Machine intelligence decrypts β-lapachone as an allosteric 5-lipoxygenase inhibitor T Rodrigues, M Werner, J Roth, EHG da Cruz, MC Marques, P Akkapeddi, ... Chemical Science 9 (34), 6899-6903, 2018 | 73 | 2018 |
Efficient and irreversible antibody–cysteine bioconjugation using carbonylacrylic reagents B Bernardim, MJ Matos, X Ferhati, I Compañón, A Guerreiro, P Akkapeddi, ... Nature Protocols 14 (1), 86-99, 2019 | 67 | 2019 |
A Biodegradable Polycationic Paint that Kills Bacteria in Vitro and in Vivo J Hoque, P Akkapeddi, C Ghosh, DSSM Uppu, J Haldar ACS Applied Materials & Interfaces 8 (43), 29298-29309, 2016 | 60 | 2016 |
A fully human anti-IL-7Rα antibody promotes antitumor activity against T-cell acute lymphoblastic leukemia P Akkapeddi, R Fragoso, JA Hixon, AS Ramalho, ML Oliveira, T Carvalho, ... Leukemia 33 (9), 2155-2168, 2019 | 52 | 2019 |
From the outside, from within: Biological and therapeutic relevance of signal transduction in T-cell acute lymphoblastic leukemia ML Oliveira, P Akkapeddi, I Alcobia, AR Almeida, BA Cardoso, R Fragoso, ... Cellular signalling 38, 10-25, 2017 | 36 | 2017 |
Creating MHC-restricted neoantigens with covalent inhibitors that can be targeted by immune therapy T Hattori, L Maso, KY Araki, A Koide, J Hayman, P Akkapeddi, I Bang, ... Cancer discovery 13 (1), 132-145, 2023 | 35 | 2023 |
NRARP displays either pro-or anti-tumoral roles in T-cell acute lymphoblastic leukemia depending on Notch and Wnt signaling I Pinto, M Duque, J Gonçalves, P Akkapeddi, ML Oliveira, R Cabrita, ... Oncogene 39 (5), 975-986, 2020 | 22 | 2020 |
One-pot stapling of interchain disulfides of antibodies using an isobutylene motif S Sun, P Akkapeddi, MC Marques, N Martínez-Sáez, VM Torres, ... Organic & Biomolecular Chemistry 17 (7), 2005-2012, 2019 | 20 | 2019 |
CD98hc is a target for brain delivery of biotherapeutics KS Chew, RC Wells, A Moshkforoush, D Chan, KJ Lechtenberg, HL Tran, ... nature communications 14 (1), 5053, 2023 | 17 | 2023 |
Monobodies as tool biologics for accelerating target validation and druggable site discovery P Akkapeddi, KW Teng, S Koide RSC Medicinal Chemistry 12 (11), 1839-1853, 2021 | 15 | 2021 |
Venkateswarlu Yarlagadda J Hoque, P Akkapeddi, V Yadav, GB Manjunath, DSSM Uppu, MM Konai Kaustuv Sanyal, Jayanta Haldar. Broad spectrum antibacterial and antifungal …, 2015 | 12 | 2015 |