Targeting the ANG2/TIE2 axis inhibits tumor growth and metastasis by impairing angiogenesis and disabling rebounds of proangiogenic myeloid cells R Mazzieri, F Pucci, D Moi, E Zonari, A Ranghetti, A Berti, LS Politi, ... Cancer cell 19 (4), 512-526, 2011 | 719 | 2011 |
Latent transforming growth factor-β: structural features and mechanisms of activation JS Munger, JG Harpel, PE Gleizes, R Mazzieri, I Nunes, DB Rifkin Kidney international 51 (5), 1376-1382, 1997 | 715 | 1997 |
Targeted genome editing in human repopulating haematopoietic stem cells P Genovese, G Schiroli, G Escobar, T Di Tomaso, C Firrito, A Calabria, ... Nature 510 (7504), 235-240, 2014 | 693 | 2014 |
Latent transforming growth factor β-binding protein 1 interacts with fibrillin and is a microfibril-associated protein Z Isogai, RN Ono, S Ushiro, DR Keene, Y Chen, R Mazzieri, ... Journal of Biological Chemistry 278 (4), 2750-2757, 2003 | 674 | 2003 |
Identification of proangiogenic TIE2-expressing monocytes (TEMs) in human peripheral blood and cancer MA Venneri, MD Palma, M Ponzoni, F Pucci, C Scielzo, E Zonari, ... Blood, The Journal of the American Society of Hematology 109 (12), 5276-5285, 2007 | 607 | 2007 |
Control of type IV collagenase activity by components of the urokinase–plasmin system: a regulatory mechanism with cell‐bound reactants R Mazzieri, L Masiero, L Zanetta, S Monea, M Onisto, S Garbisa, ... The EMBO journal, 1997 | 526 | 1997 |
TGF-β latency: biological significance and mechanisms of activation PE Gleizes, JS Munger, I Nunes, JG Harpel, R Mazzieri, I Noguera, ... Stem cells 15 (3), 190-197, 1997 | 415 | 1997 |
Vascular Endothelial Growth Factor Increases Urokinase Receptor Expression in Vascular Endothelial Cells (∗) SJ Mandriota, G Seghezzi, JD Vassalli, N Ferrara, S Wasi, R Mazzieri, ... Journal of Biological Chemistry 270 (17), 9709-9716, 1995 | 408 | 1995 |
Tumor-targeted interferon-α delivery by Tie2-expressing monocytes inhibits tumor growth and metastasis M De Palma, R Mazzieri, LS Politi, F Pucci, E Zonari, G Sitia, S Mazzoleni, ... Cancer cell 14 (4), 299-311, 2008 | 339 | 2008 |
Proteolytic control of growth factor availability DB Rifkin, R Mazzieri, JS Munger, I Noguera, J Sung Apmis 107 (1‐6), 80-85, 1999 | 245 | 1999 |
Expression of the urokinase receptor in vascular endothelial cells is stimulated by basic fibroblast growth factor. P Mignatti, R Mazzieri, DB Rifkin The Journal of cell biology 113 (5), 1193-1201, 1991 | 234 | 1991 |
Plasticity of type I interferon-mediated responses in cancer therapy: from anti-tumor immunity to resistance M Budhwani, R Mazzieri, R Dolcetti Frontiers in oncology 8, 322, 2018 | 193 | 2018 |
Identification and characterization of an eight-cysteine repeat of the latent transforming growth factor-β binding protein-1 that mediates bonding to the latent transforming … PE Gleizes, RC Beavis, R Mazzieri, B Shen, DB Rifkin Journal of Biological Chemistry 271 (47), 29891-29896, 1996 | 185 | 1996 |
Frontiers in the treatment of glioblastoma: Past, present and emerging TI Janjua, P Rewatkar, A Ahmed-Cox, I Saeed, FM Mansfeld, ... Advanced drug delivery reviews 171, 108-138, 2021 | 160 | 2021 |
Perturbation of transforming growth factor (TGF)-ß1 association with latent TGF-β binding protein yields inflammation and tumors K Yoshinaga, H Obata, V Jurukovski, R Mazzieri, Y Chen, L Zilberberg, ... Proceedings of the National Academy of Sciences 105 (48), 18758-18763, 2008 | 132 | 2008 |
Endocytosis inhibition in humans to improve responses to ADCC-mediating antibodies HY Chew, PO De Lima, JLG Cruz, B Banushi, G Echejoh, L Hu, ... Cell 180 (5), 895-914. e27, 2020 | 125 | 2020 |
A role for miR-155 in enabling tumor-infiltrating innate immune cells to mount effective antitumor responses in mice E Zonari, F Pucci, M Saini, R Mazzieri, LS Politi, B Gentner, L Naldini Blood, The Journal of the American Society of Hematology 122 (2), 243-252, 2013 | 118 | 2013 |
Long-pentraxin 3 derivative as a small-molecule FGF trap for cancer therapy R Ronca, A Giacomini, E Di Salle, D Coltrini, K Pagano, L Ragona, ... Cancer cell 28 (2), 225-239, 2015 | 117 | 2015 |
Hypomorphic mutation of the TALE gene Prep1 (pKnox1) causes a major reduction of Pbx and Meis proteins and a pleiotropic embryonic phenotype E Ferretti, JC Villaescusa, P Di Rosa, LC Fernandez-Diaz, E Longobardi, ... Molecular and cellular biology, 2006 | 116 | 2006 |
Genetic engineering of hematopoiesis for targeted IFN-α delivery inhibits breast cancer progression G Escobar, D Moi, A Ranghetti, P Ozkal-Baydin, ML Squadrito, ... Science translational medicine 6 (217), 217ra3-217ra3, 2014 | 115 | 2014 |