| Evaluation of the therapeutic usefulness of botulinum neurotoxin B, C1, E, and F compared with the long lasting type A: basis for distinct durations of inhibition of exocytosis … PG Foran, N Mohammed, GO Lisk, S Nagwaney, GW Lawrence, ... Journal of biological chemistry 278 (2), 1363-1371, 2003 | 419 | 2003 |
| Botulinum neurotoxin C1 cleaves both syntaxin and SNAP-25 in intact and permeabilized chromaffin cells: correlation with its blockade of catecholamine release P Foran, GW Lawrence, CC Shone, KA Foster, JO Dolly Biochemistry 35 (8), 2630-2636, 1996 | 333 | 1996 |
| Synaptobrevin I mediates exocytosis of CGRP from sensory neurons and inhibition by botulinum toxins reflects their anti-nociceptive potential J Meng, J Wang, G Lawrence, JO Dolly Journal of cell science 120 (16), 2864-2874, 2007 | 315 | 2007 |
| Activation of TRPV1 mediates calcitonin gene-related peptide release, which excites trigeminal sensory neurons and is attenuated by a retargeted botulinum toxin with anti … J Meng, SV Ovsepian, J Wang, M Pickering, A Sasse, KR Aoki, ... Journal of Neuroscience 29 (15), 4981-4992, 2009 | 271 | 2009 |
| Novel chimeras of botulinum neurotoxins A and E unveil contributions from the binding, translocation, and protease domains to their functional characteristics J Wang, J Meng, GW Lawrence, TH Zurawski, A Sasse, MDO Bodeker, ... Journal of Biological Chemistry 283 (25), 16993-17002, 2008 | 135 | 2008 |
| Neuro-exocytosis: botulinum toxins as inhibitory probes and versatile therapeutics JO Dolly, GW Lawrence, J Meng, J Wang, SV Ovsepian Current opinion in pharmacology 9 (3), 326-335, 2009 | 109 | 2009 |
| A dileucine in the protease of botulinum toxin A underlies its long-lived neuroparalysis: transfer of longevity to a novel potential therapeutic J Wang, TH Zurawski, J Meng, G Lawrence, WM Olango, DP Finn, ... Journal of Biological Chemistry 286 (8), 6375-6385, 2011 | 97 | 2011 |
| Rescue of exocytosis in botulinum toxin A-poisoned chromaffin cells by expression of cleavage-resistant SNAP-25: identification of the minimal essential C-terminal residues GA O'Sullivan, N Mohammed, PG Foran, GW Lawrence, JO Dolly Journal of Biological Chemistry 274 (52), 36897-36904, 1999 | 91 | 1999 |
| Botulinum A and the light chain of tetanus toxins inhibit distinct stages of Mg· ATP‐dependent catecholamine exocytosis from permeabilised chromaffin cells GW Lawrence, U Weller, JO Dolly European journal of biochemistry 222 (2), 325-333, 1994 | 79 | 1994 |
| Excitatory cholinergic and purinergic signaling in bladder are equally susceptible to botulinum neurotoxin a consistent with co-release of transmitters from efferent fibers GW Lawrence, KR Aoki, JO Dolly Journal of Pharmacology and Experimental Therapeutics 334 (3), 1080-1086, 2010 | 71 | 2010 |
| Importance of two adjacent C-terminal sequences of SNAP-25 in exocytosis from intact and permeabilized chromaffin cells revealed by inhibition with botulinum neurotoxins A and E GW Lawrence, P Foran, N Mohammed, BR DasGupta, JO Dolly Biochemistry 36 (11), 3061-3067, 1997 | 66 | 1997 |
| Extravesicular intraneuronal migration of internalized botulinum neurotoxins without detectable inhibition of distal neurotransmission GW Lawrence, SV Ovsepian, J Wang, KR Aoki, JO Dolly Biochemical Journal 441 (1), 443-452, 2012 | 65 | 2012 |
| Probing the process of transmitter release with botulinum and tetanus neurotoxins JO Dolly, A de Paiva, P Foran, G Lawrence, P Daniels-Holgate, ... Seminars in Neuroscience 6 (3), 149-158, 1994 | 62 | 1994 |
| Distinct Exocytotic Responses of Intact and Permeabilised Chromaffin Cells After Cleavage of the 25‐kDa Synaptosomal‐Associated Protein (SNAP‐25) or Synaptobrevin by Botulinum … GW Lawrence, P Foran, JO Dolly European journal of biochemistry 236 (3), 877-886, 1996 | 53 | 1996 |
| Novel chimeras of botulinum and tetanus neurotoxins yield insights into their distinct sites of neuroparalysis J Wang, TH Zurawski, J Meng, GW Lawrence, KR Aoki, L Wheeler, ... The FASEB Journal 26 (12), 5035-5048, 2012 | 46 | 2012 |
| Botulinum toxin A detrusor injections reduce postsynaptic muscular M2, M3, P2X2, and P2X3 receptors in children and adolescents who have neurogenic detrusor overactivity: a … H Schulte-Baukloh, J Priefert, HH Knispel, GW Lawrence, K Miller, ... Urology 81 (5), 1052-1057, 2013 | 44 | 2013 |
| Blockade by botulinum neurotoxin B of catecholamine release from adrenochromaffin cells correlates with its cleavage of synaptobrevin and a homolog present on the granules P Foran, G Lawrence, JO Dolly Biochemistry 34 (16), 5494-5503, 1995 | 44 | 1995 |
| Recombinant forms of tetanus toxin engineered for examining and exploiting neuronal trafficking pathways Y Li, P Foran, G Lawrence, N Mohammed, G Lisk, R Aoki, O Dolly Journal of Biological Chemistry 276 (33), 31394-31401, 2001 | 41 | 2001 |
| Trachynilysin mediates SNARE-dependent release of catecholamines from chromaffin cells via external and stored Ca2+ FA Meunier, C Mattei, P Chameau, G Lawrence, C Colasante, AS Kreger, ... Journal of Cell Science 113 (7), 1119-1125, 2000 | 41 | 2000 |
| Two protein trafficking processes at motor nerve endings unveiled by botulinum neurotoxin E G Lawrence, J Wang, CKNK Chion, KR Aoki, JO Dolly Journal of Pharmacology and Experimental Therapeutics 320 (1), 410-418, 2007 | 36 | 2007 |
