An anticancer drug suppresses the primary nucleation reaction that initiates the production of the toxic Aβ42 aggregates linked with Alzheimer’s disease J Habchi, P Arosio, M Perni, AR Costa, M Yagi-Utsumi, P Joshi, S Chia, ... Science advances 2 (2), e1501244, 2016 | 223 | 2016 |
Druggability of intrinsically disordered proteins P Joshi, M Vendruscolo Intrinsically disordered proteins studied by NMR spectroscopy, 383-400, 2015 | 68 | 2015 |
A fragment-based method of creating small-molecule libraries to target the aggregation of intrinsically disordered proteins P Joshi, S Chia, J Habchi, TPJ Knowles, CM Dobson, M Vendruscolo ACS combinatorial science 18 (3), 144-153, 2016 | 38 | 2016 |
A dopamine metabolite stabilizes neurotoxic amyloid-β oligomers R Cataldi, S Chia, K Pisani, FS Ruggeri, CK Xu, T Šneideris, M Perni, ... Communications biology 4 (1), 19, 2021 | 34 | 2021 |
Two human metabolites rescue a C. elegans model of Alzheimer’s disease via a cytosolic unfolded protein response P Joshi, M Perni, R Limbocker, B Mannini, S Casford, S Chia, J Habchi, ... Communications Biology 4 (1), 843, 2021 | 10 | 2021 |
Pathway Analysis of Acinetobacter baylyi: A Combined Bioinformatic and Genomics Approach S Singh, P Joshi, BA Chopade Chemical Biology & Drug Design 78 (5), 893-905, 2011 | 5 | 2011 |
AA, Dobson, CM, Knowles, TPJ, and Vendruscolo, M.(2016) An anticancer drug suppresses the primary nucleation reaction that initiates the production of the toxic Aβ42 aggregates … J Habchi, P Arosio, M Perni, AR Costa, M Yagi-Utsumi, P Joshi, S Chia, ... Sci. Adv 2, e1501244, 0 | 5 | |
Choke point analysis of the metabolic pathways of Acinetobacter baylyi: a genomics approach to assess potential drug targets S Singh, P Joshi, BA Chopade Journal of Bioinformatics and Sequence Analysis 1 (3), 041-045, 2009 | 4 | 2009 |
Vitamin A and vitamin E metabolites comodulate amyloid-β aggregation P Joshi, S Chia, X Yang, M Perni, J Habchi, M Vendruscolo biorxiv, 2021 | 2 | 2021 |
Publisher Correction: A dopamine metabolite stabilizes neurotoxic amyloid-β oligomers R Cataldi, S Chia, K Pisani, FS Ruggeri, CK Xu, T Šneideris, M Perni, ... Communications Biology 4, 2021 | 1 | 2021 |
Combinations of Vitamin A and Vitamin E Metabolites Confer Resilience against Amyloid-β Aggregation P Joshi, S Chia, X Yang, M Perni, JM Gabriel, M Gilmer, R Limbocker, ... ACS Chemical Neuroscience 14 (4), 657-666, 2023 | | 2023 |
Counteraction of amyloid-β aggregation by vitamin A and E metabolites in a crowded environment P Joshi, S Chia, X Yang, M Perni, J Habchi, M Vendruscolo Biophysical Journal 121 (3), 351a, 2022 | | 2022 |
Endogenous metabolites rescue a C. elegans model of Alzheimer's disease by triggering a heat shock response P Joshi, M Perni, R Limbocker, B Mannini, S Casford, S Chia, J Labbadia, ... FEBS OPEN BIO 9, 225-225, 2019 | | 2019 |
Glaucoma as a protein misfolding disease: an investigation of its metastable proteome P Joshi, M Vendruscolo JOURNAL OF ALZHEIMERS DISEASE 64 (3), 1032-1033, 2018 | | 2018 |
Women in STEM: Emerging Mountains in the Great Indian Entrepreneurship Landscape RN Pradhan, P Joshi Bookwell Delhi, 2017 | | 2017 |
Targeting intrinsically disordered proteins associated with neurodegenerative diseases: a strategy towards drug discovery P Joshi University of Cambridge, 2015 | | 2015 |
Structural and Mechanistic Analyses of the Effects of Small Compounds on Amyloid Beta Self-Assembly J Habchi, P Joshi, A Spilotros, D Svergun, M Vendruscolo Biophysical Journal 106 (2), 269a, 2014 | | 2014 |