HDAC6 regulates Hsp90 acetylation and chaperone-dependent activation of glucocorticoid receptor JJ Kovacs, PJM Murphy, S Gaillard, X Zhao, JT Wu, CV Nicchitta, ... Molecular cell 18 (5), 601-607, 2005 | 1327 | 2005 |
Sensitivity of mature Erbb2 to geldanamycin is conferred by its kinase domain and is mediated by the chaperone protein Hsp90 W Xu, E Mimnaugh, MFN Rosser, C Nicchitta, M Marcu, Y Yarden, ... Journal of biological chemistry 276 (5), 3702-3708, 2001 | 425 | 2001 |
Scavenger receptor-A mediates gp96/GRP94 and calreticulin internalization by antigen-presenting cells B Berwin, JP Hart, S Rice, C Gass, SV Pizzo, SR Post, CV Nicchitta The EMBO Journal 22 (22), 6127-6136, 2003 | 331 | 2003 |
Translocation of sickle cell erythrocyte microRNAs into Plasmodium falciparum inhibits parasite translation and contributes to malaria resistance G LaMonte, N Philip, J Reardon, JR Lacsina, W Majoros, L Chapman, ... Cell host & microbe 12 (2), 187-199, 2012 | 322 | 2012 |
Diversity and selectivity in mRNA translation on the endoplasmic reticulum DW Reid, CV Nicchitta Nature reviews Molecular cell biology 16 (4), 221-231, 2015 | 274 | 2015 |
The DRiP hypothesis decennial: support, controversy, refinement and extension JW Yewdell, CV Nicchitta Trends in immunology 27 (8), 368-373, 2006 | 261 | 2006 |
Lumenal proteins of the mammalian endoplasmic reticulum are required to complete protein translocation CV Nicchitta, G Blobel Cell 73 (5), 989-998, 1993 | 238 | 1993 |
Primary role for endoplasmic reticulum-bound ribosomes in cellular translation identified by ribosome profiling DW Reid, CV Nicchitta Journal of Biological Chemistry 287 (8), 5518-5527, 2012 | 209 | 2012 |
Spermine. A regulator of mitochondrial calcium cycling. CV Nicchitta, JR Williamson Journal of Biological Chemistry 259 (21), 12978-12983, 1984 | 196 | 1984 |
Partitioning and translation of mRNAs encoding soluble proteins on membrane-bound ribosomes RS Lerner, RM Seiser, T Zheng, PJ Lager, MC Reedy, JD Keene, ... Rna 9 (9), 1123-1137, 2003 | 181 | 2003 |
Heat shock protein 96 is elevated in rheumatoid arthritis and activates macrophages primarily via TLR2 signaling QQ Huang, R Sobkoviak, AR Jockheck-Clark, B Shi, AM Mandelin, ... The Journal of Immunology 182 (8), 4965-4973, 2009 | 180 | 2009 |
Rare codons regulate KRas oncogenesis BL Lampson, NLK Pershing, JA Prinz, JR Lacsina, WF Marzluff, ... Current Biology 23 (1), 70-75, 2013 | 172 | 2013 |
Signal sequence-and translation-independent mRNA localization to the endoplasmic reticulum B Pyhtila, T Zheng, PJ Lager, JD Keene, MC Reedy, CV Nicchitta Rna 14 (3), 445-453, 2008 | 166 | 2008 |
Structure of the N-terminal domain of GRP94: Basis for ligand specificity and regulation KL Soldano, A Jivan, CV Nicchitta, DT Gewirth Journal of Biological Chemistry 278 (48), 48330-48338, 2003 | 166 | 2003 |
Biochemical, cell biological and immunological issues surrounding the endoplasmic reticulum chaperone GRP94/gp96 CV Nicchitta Current opinion in immunology 10 (1), 103-109, 1998 | 162 | 1998 |
Interaction of TLR2 and TLR4 ligands with the N-terminal domain of Gp96 amplifies innate and adaptive immune responses T Warger, N Hilf, G Rechtsteiner, P Haselmayer, DM Carrick, H Jonuleit, ... Journal of Biological Chemistry 281 (32), 22545-22553, 2006 | 158 | 2006 |
Calreticulin displays in vivo peptide-binding activity and can elicit CTL responses against bound peptides S Nair, PA Wearsch, DA Mitchell, JJ Wassenberg, E Gilboa, CV Nicchitta The Journal of Immunology 162 (11), 6426-6432, 1999 | 149 | 1999 |
Re-evaluating the role of heat-shock protein–peptide interactions in tumour immunity CV Nicchitta Nature Reviews Immunology 3 (5), 427-432, 2003 | 140 | 2003 |
GRP94/gp96 elicits ERK activation in murine macrophages: a role for endotoxin contamination in NF-κB activation and nitric oxide production RC Reed, B Berwin, JP Baker, CV Nicchitta Journal of Biological Chemistry 278 (34), 31853-31860, 2003 | 137 | 2003 |
The unfolded protein response triggers selective mRNA release from the endoplasmic reticulum DW Reid, Q Chen, ASL Tay, S Shenolikar, CV Nicchitta Cell 158 (6), 1362-1374, 2014 | 135 | 2014 |