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George R Young
George R Young
MRC Laboratory of Medical Sciences
在 lms.mrc.ac.uk 的电子邮件经过验证
标题
引用次数
引用次数
年份
The axolotl genome and the evolution of key tissue formation regulators
S Nowoshilow, S Schloissnig, JF Fei, A Dahl, AWC Pang, M Pippel, ...
Nature 554 (7690), 50-55, 2018
5342018
Z-nucleic-acid sensing triggers ZBP1-dependent necroptosis and inflammation
H Jiao, L Wachsmuth, S Kumari, R Schwarzer, J Lin, RO Eren, A Fisher, ...
Nature 580 (7803), 391-395, 2020
3012020
Resurrection of endogenous retroviruses in antibody-deficient mice
GR Young, U Eksmond, R Salcedo, L Alexopoulou, JP Stoye, G Kassiotis
Nature 491 (7426), 774-778, 2012
2352012
The genome of Schmidtea mediterranea and the evolution of core cellular mechanisms
MA Grohme, S Schloissnig, A Rozanski, M Pippel, GR Young, S Winkler, ...
Nature 554 (7690), 56-61, 2018
2172018
ADAR1 averts fatal type I interferon induction by ZBP1
H Jiao, L Wachsmuth, S Wolf, J Lohmann, M Nagata, GG Kaya, ...
Nature 607 (7920), 776-783, 2022
1012022
Are human endogenous retroviruses pathogenic? An approach to testing the hypothesis
GR Young, JP Stoye, G Kassiotis
Bioessays 35 (9), 794-803, 2013
1012013
Tissue-specific and interferon-inducible expression of nonfunctional ACE2 through endogenous retroelement co-option
KW Ng, J Attig, W Bolland, GR Young, J Major, AG Wrobel, S Gamblin, ...
Nature genetics 52 (12), 1294-1302, 2020
962020
Antibodies against endogenous retroviruses promote lung cancer immunotherapy
KW Ng, J Boumelha, KSS Enfield, J Almagro, H Cha, O Pich, T Karasaki, ...
Nature 616 (7957), 563-573, 2023
902023
Adenosine-to-inosine editing of endogenous Z-form RNA by the deaminase ADAR1 prevents spontaneous MAVS-dependent type I interferon responses
Q Tang, RE Rigby, GR Young, AK Hvidt, T Davis, TK Tan, A Bridgeman, ...
Immunity 54 (9), 1961-1975. e5, 2021
812021
LTR retroelement expansion of the human cancer transcriptome and immunopeptidome revealed by de novo transcript assembly
J Attig, GR Young, L Hosie, D Perkins, V Encheva-Yokoya, JP Stoye, ...
Genome research 29 (10), 1578-1590, 2019
762019
Opposing Development of Cytotoxic and Follicular Helper CD4 T Cells Controlled by the TCF-1-Bcl6 Nexus
T Donnarumma, GR Young, J Merkenschlager, U Eksmond, N Bongard, ...
Cell Reports 17 (6), 1571-1583, 2016
612016
Negative selection by an endogenous retrovirus promotes a higher-avidity CD4+ T cell response to retroviral infection
GR Young, MJ Ploquin, U Eksmond, M Wadwa, JP Stoye, G Kassiotis
PLoS Pathog 8 (5), e1002709, 2012
612012
HIV-1 interacts with human endogenous retrovirus K (HML-2) envelopes derived from human primary lymphocytes
D Brinzevich, GR Young, R Sebra, J Ayllon, SM Maio, G Deikus, BK Chen, ...
Journal of virology 88 (11), 6213-6223, 2014
542014
Soluble PD-L1 generated by endogenous retroelement exaptation is a receptor antagonist
KW Ng, J Attig, GR Young, E Ottina, SI Papamichos, I Kotsianidis, ...
elife 8, e50256, 2019
522019
Microarray analysis reveals global modulation of endogenous retroelement transcription by microbes
GR Young, B Mavrommatis, G Kassiotis
Retrovirology 11 (1), 59, 2014
502014
Permissive selection followed by affinity-based proliferation of GC light zone B cells dictates cell fate and ensures clonal breadth
R Nakagawa, A Toboso-Navasa, M Schips, G Young, L Bhaw-Rosun, ...
Proceedings of the National Academy of Sciences 118 (2), e2016425118, 2021
482021
HIV-1 Infection of Primary CD4+ T Cells Regulates the Expression of Specific Human Endogenous Retrovirus HERV-K (HML-2) Elements
GR Young, SN Terry, L Manganaro, A Cuesta-Dominguez, G Deikus, ...
Journal of virology 92 (1), e01507-17, 2018
382018
Physiological and Pathological Transcriptional Activation of Endogenous Retroelements Assessed By RNA-Sequencing of B lymphocytes
J Attig, GR Young, J Stoye, G Kassiotis
Frontiers in Microbiology 8, 2489, 2017
372017
SARS-CoV-2 ORF6 disrupts innate immune signalling by inhibiting cellular mRNA export
R Hall, A Guedán, MW Yap, GR Young, R Harvey, JP Stoye, KN Bishop
PLoS pathogens 18 (8), e1010349, 2022
322022
Evolutionary journey of the retroviral restriction gene Fv1
GR Young, MW Yap, JR Michaux, SJ Steppan, JP Stoye
Proceedings of the National Academy of Sciences 115 (40), 10130-10135, 2018
252018
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