The axolotl genome and the evolution of key tissue formation regulators S Nowoshilow, S Schloissnig, JF Fei, A Dahl, AWC Pang, M Pippel, ... Nature 554 (7690), 50-55, 2018 | 534 | 2018 |
Z-nucleic-acid sensing triggers ZBP1-dependent necroptosis and inflammation H Jiao, L Wachsmuth, S Kumari, R Schwarzer, J Lin, RO Eren, A Fisher, ... Nature 580 (7803), 391-395, 2020 | 301 | 2020 |
Resurrection of endogenous retroviruses in antibody-deficient mice GR Young, U Eksmond, R Salcedo, L Alexopoulou, JP Stoye, G Kassiotis Nature 491 (7426), 774-778, 2012 | 235 | 2012 |
The genome of Schmidtea mediterranea and the evolution of core cellular mechanisms MA Grohme, S Schloissnig, A Rozanski, M Pippel, GR Young, S Winkler, ... Nature 554 (7690), 56-61, 2018 | 217 | 2018 |
ADAR1 averts fatal type I interferon induction by ZBP1 H Jiao, L Wachsmuth, S Wolf, J Lohmann, M Nagata, GG Kaya, ... Nature 607 (7920), 776-783, 2022 | 101 | 2022 |
Are human endogenous retroviruses pathogenic? An approach to testing the hypothesis GR Young, JP Stoye, G Kassiotis Bioessays 35 (9), 794-803, 2013 | 101 | 2013 |
Tissue-specific and interferon-inducible expression of nonfunctional ACE2 through endogenous retroelement co-option KW Ng, J Attig, W Bolland, GR Young, J Major, AG Wrobel, S Gamblin, ... Nature genetics 52 (12), 1294-1302, 2020 | 96 | 2020 |
Antibodies against endogenous retroviruses promote lung cancer immunotherapy KW Ng, J Boumelha, KSS Enfield, J Almagro, H Cha, O Pich, T Karasaki, ... Nature 616 (7957), 563-573, 2023 | 90 | 2023 |
Adenosine-to-inosine editing of endogenous Z-form RNA by the deaminase ADAR1 prevents spontaneous MAVS-dependent type I interferon responses Q Tang, RE Rigby, GR Young, AK Hvidt, T Davis, TK Tan, A Bridgeman, ... Immunity 54 (9), 1961-1975. e5, 2021 | 81 | 2021 |
LTR retroelement expansion of the human cancer transcriptome and immunopeptidome revealed by de novo transcript assembly J Attig, GR Young, L Hosie, D Perkins, V Encheva-Yokoya, JP Stoye, ... Genome research 29 (10), 1578-1590, 2019 | 76 | 2019 |
Opposing Development of Cytotoxic and Follicular Helper CD4 T Cells Controlled by the TCF-1-Bcl6 Nexus T Donnarumma, GR Young, J Merkenschlager, U Eksmond, N Bongard, ... Cell Reports 17 (6), 1571-1583, 2016 | 61 | 2016 |
Negative selection by an endogenous retrovirus promotes a higher-avidity CD4+ T cell response to retroviral infection GR Young, MJ Ploquin, U Eksmond, M Wadwa, JP Stoye, G Kassiotis PLoS Pathog 8 (5), e1002709, 2012 | 61 | 2012 |
HIV-1 interacts with human endogenous retrovirus K (HML-2) envelopes derived from human primary lymphocytes D Brinzevich, GR Young, R Sebra, J Ayllon, SM Maio, G Deikus, BK Chen, ... Journal of virology 88 (11), 6213-6223, 2014 | 54 | 2014 |
Soluble PD-L1 generated by endogenous retroelement exaptation is a receptor antagonist KW Ng, J Attig, GR Young, E Ottina, SI Papamichos, I Kotsianidis, ... elife 8, e50256, 2019 | 52 | 2019 |
Microarray analysis reveals global modulation of endogenous retroelement transcription by microbes GR Young, B Mavrommatis, G Kassiotis Retrovirology 11 (1), 59, 2014 | 50 | 2014 |
Permissive selection followed by affinity-based proliferation of GC light zone B cells dictates cell fate and ensures clonal breadth R Nakagawa, A Toboso-Navasa, M Schips, G Young, L Bhaw-Rosun, ... Proceedings of the National Academy of Sciences 118 (2), e2016425118, 2021 | 48 | 2021 |
HIV-1 Infection of Primary CD4+ T Cells Regulates the Expression of Specific Human Endogenous Retrovirus HERV-K (HML-2) Elements GR Young, SN Terry, L Manganaro, A Cuesta-Dominguez, G Deikus, ... Journal of virology 92 (1), e01507-17, 2018 | 38 | 2018 |
Physiological and Pathological Transcriptional Activation of Endogenous Retroelements Assessed By RNA-Sequencing of B lymphocytes J Attig, GR Young, J Stoye, G Kassiotis Frontiers in Microbiology 8, 2489, 2017 | 37 | 2017 |
SARS-CoV-2 ORF6 disrupts innate immune signalling by inhibiting cellular mRNA export R Hall, A Guedán, MW Yap, GR Young, R Harvey, JP Stoye, KN Bishop PLoS pathogens 18 (8), e1010349, 2022 | 32 | 2022 |
Evolutionary journey of the retroviral restriction gene Fv1 GR Young, MW Yap, JR Michaux, SJ Steppan, JP Stoye Proceedings of the National Academy of Sciences 115 (40), 10130-10135, 2018 | 25 | 2018 |