Complete remission and early death after intensive chemotherapy in patients aged 60 years or older with acute myeloid leukaemia: a web-based application for prediction of outcomes U Krug, C Röllig, A Koschmieder, A Heinecke, MC Sauerland, M Schaich, ... The Lancet 376 (9757), 2000-2008, 2010 | 352 | 2010 |
BISMA-Fast and accurate bisulfite sequencing data analysis of individual clones from unique and repetitive sequences C Rohde, Y Zhang, R Reinhardt, A Jeltsch BMC bioinformatics 11, 1-12, 2010 | 264 | 2010 |
Loss of the histone methyltransferase EZH2 induces resistance to multiple drugs in acute myeloid leukemia S Göllner, T Oellerich, S Agrawal-Singh, T Schenk, HU Klein, C Rohde, ... Nature medicine 23 (1), 69-78, 2017 | 231 | 2017 |
DNA methylation analysis of chromosome 21 gene promoters at single base pair and single allele resolution Y Zhang, C Rohde, S Tierling, TP Jurkowski, C Bock, D Santacruz, ... PLoS genetics 5 (3), e1000438, 2009 | 202 | 2009 |
Chimeric DNA methyltransferases target DNA methylation to specific DNA sequences and repress expression of target genes F Li, M Papworth, M Minczuk, C Rohde, Y Zhang, S Ragozin, A Jeltsch Nucleic acids research 35 (1), 100-112, 2007 | 169 | 2007 |
AML1-ETO requires enhanced C/D box snoRNA/RNP formation to induce self-renewal and leukaemia F Zhou, Y Liu, C Rohde, C Pauli, D Gerloff, M Köhn, D Misiak, N Bäumer, ... Nature cell biology 19 (7), 844-855, 2017 | 154 | 2017 |
Alarmins MRP8 and MRP14 induce stress tolerance in phagocytes under sterile inflammatory conditions J Austermann, J Friesenhagen, SK Fassl, T Ortkras, J Burgmann, ... Cell reports 9 (6), 2112-2123, 2014 | 117 | 2014 |
Epigenetic dysregulation of KCa3.1 channels induces poor prognosis in lung cancer E Bulk, AS Ay, M Hammadi, H Ouadid‐Ahidouch, S Schelhaas, A Hascher, ... International journal of cancer 137 (6), 1306-1317, 2015 | 106 | 2015 |
Non-imprinted allele-specific DNA methylation on human autosomes Y Zhang, C Rohde, R Reinhardt, C Voelcker-Rehage, A Jeltsch Genome biology 10, 1-11, 2009 | 101 | 2009 |
DNA methylation analysis by bisulfite conversion, cloning, and sequencing of individual clones Y Zhang, C Rohde, S Tierling, H Stamerjohanns, R Reinhardt, J Walter, ... DNA Methylation: Methods and Protocols, 177-187, 2009 | 101 | 2009 |
DNA methylation changes are a late event in acute promyelocytic leukemia and coincide with loss of transcription factor binding T Schoofs, C Rohde, K Hebestreit, HU Klein, S Göllner, I Schulze, ... Blood, The Journal of the American Society of Hematology 121 (1), 178-187, 2013 | 82 | 2013 |
Prognostic impact of Bcl-2 depends on tumor histology and expression of MALAT-1 lncRNA in non–small-cell lung cancer LH Schmidt, D Goerlich, T Spieker, C Rohde, M Schuler, M Mohr, ... Journal of Thoracic Oncology 9 (9), 1294-1304, 2014 | 79 | 2014 |
Bisulfite sequencing Data Presentation and Compilation (BDPC) web server—a useful tool for DNA methylation analysis C Rohde, Y Zhang, TP Jurkowski, H Stamerjohanns, R Reinhardt, ... Nucleic acids research 36 (5), e34, 2008 | 77 | 2008 |
Site-specific methylation of 18S ribosomal RNA by SNORD42A is required for acute myeloid leukemia cell proliferation C Pauli, Y Liu, C Rohde, C Cui, D Fijalkowska, D Gerloff, C Walter, ... Blood, The Journal of the American Society of Hematology 135 (23), 2059-2070, 2020 | 64 | 2020 |
Enantiomer-specific and paracrine leukemogenicity of mutant IDH metabolite 2-hydroxyglutarate A Chaturvedi, MM Araujo Cruz, N Jyotsana, A Sharma, R Goparaju, ... Leukemia 30 (8), 1708-1715, 2016 | 57 | 2016 |
Hepatic leukemia factor is a novel leukemic stem cell regulator in DNMT3A, NPM1, and FLT3-ITD triple-mutated AML S Garg, A Reyes-Palomares, L He, A Bergeron, VP Lavallée, S Lemieux, ... Blood, The Journal of the American Society of Hematology 134 (3), 263-276, 2019 | 52 | 2019 |
Venetoclax synergizes with gilteritinib in FLT3 wild-type high-risk acute myeloid leukemia by suppressing MCL-1 M Janssen, C Schmidt, PM Bruch, MF Blank, C Rohde, A Waclawiczek, ... Blood, The Journal of the American Society of Hematology 140 (24), 2594-2610, 2022 | 50 | 2022 |
DNA methyltransferase inhibition reverses epigenetically embedded phenotypes in lung cancer preferentially affecting polycomb target genes A Hascher, AK Haase, K Hebestreit, C Rohde, HU Klein, M Rius, ... Clinical Cancer Research 20 (4), 814-826, 2014 | 49 | 2014 |
5-azacytidine enhances efficacy of multiple chemotherapy drugs in AML and lung cancer with modulation of CpG methylation M Füller, M Klein, E Schmidt, C Rohde, S Göllner, I Schulze, J Qianli, ... International journal of oncology 46 (3), 1192-1204, 2015 | 45 | 2015 |
Increased DNA methylation of Dnmt3b targets impairs leukemogenesis I Schulze, C Rohde, M Scheller-Wendorff, N Bäumer, A Krause, F Herbst, ... Blood, The Journal of the American Society of Hematology 127 (12), 1575-1586, 2016 | 43 | 2016 |