| Effects of hypothermia on drug disposition, metabolism, and response: a focus of hypothermia-mediated alterations on the cytochrome P450 enzyme system MA Tortorici, PM Kochanek, SM Poloyac Critical care medicine 35 (9), 2196-2204, 2007 | 467 | 2007 |
| Dual role of mitochondria in producing melatonin and driving GPCR signaling to block cytochrome c release Y Suofu, W Li, FG Jean-Alphonse, J Jia, NK Khattar, J Li, SV Baranov, ... Proceedings of the National Academy of Sciences 114 (38), E7997-E8006, 2017 | 412 | 2017 |
| A mitochondrial pathway for biosynthesis of lipid mediators YY Tyurina, SM Poloyac, VA Tyurin, AA Kapralov, J Jiang, ... Nature chemistry 6 (6), 542-552, 2014 | 166 | 2014 |
| Activation of the acute inflammatory response alters cytochrome P450 expression and eicosanoid metabolism KN Theken, Y Deng, MA Kannon, TM Miller, SM Poloyac, CR Lee Drug metabolism and disposition 39 (1), 22-29, 2011 | 146 | 2011 |
| Melatonin inhibits cytosolic mitochondrial DNA–induced neuroinflammatory signaling in accelerated aging and neurodegeneration A Jauhari, SV Baranov, Y Suofu, J Kim, T Singh, S Yablonska, F Li, ... The Journal of clinical investigation 130 (6), 3124-3136, 2020 | 131 | 2020 |
| Emerging therapies in traumatic brain injury PM Kochanek, TC Jackson, NM Ferguson, SW Carlson, DW Simon, ... Seminars in neurology 35 (01), 083-100, 2015 | 131 | 2015 |
| Lipid emulsion combined with epinephrine and vasopressin does not improve survival in a swine model of bupivacaine-induced cardiac arrest SD Hicks, DD Salcido, ES Logue, BP Suffoletto, PE Empey, SM Poloyac, ... The Journal of the American Society of Anesthesiologists 111 (1), 138-146, 2009 | 125 | 2009 |
| Evaluation of cytochrome P450-derived eicosanoids in humans with stable atherosclerotic cardiovascular disease KN Theken, RN Schuck, ML Edin, B Tran, K Ellis, A Bass, FB Lih, ... Atherosclerosis 222 (2), 530-536, 2012 | 124 | 2012 |
| Effect of leptin on cytochrome P-450, conjugation, and antioxidant enzymes in the ob/ob mouse AM Watson, SM Poloyac, G Howard, RA Blouin Drug Metabolism and Disposition 27 (6), 695-700, 1999 | 117 | 1999 |
| The effect of therapeutic hypothermia on drug metabolism and response: cellular mechanisms to organ function J Zhou, SM Poloyac Expert opinion on drug metabolism & toxicology 7 (7), 803-816, 2011 | 107 | 2011 |
| Dual role of orphan nuclear receptor pregnane X receptor in bilirubin detoxification in mice SPS Saini, Y Mu, H Gong, D Toma, H Uppal, S Ren, S Li, SM Poloyac, ... Hepatology 41 (3), 497-505, 2005 | 104 | 2005 |
| The cytochrome P450 epoxygenase pathway regulates the hepatic inflammatory response in fatty liver disease RN Schuck, W Zha, ML Edin, A Gruzdev, KC Vendrov, TM Miller, Z Xu, ... PloS one 9 (10), e110162, 2014 | 97 | 2014 |
| Mild hypothermia alters midazolam pharmacokinetics in normal healthy volunteers D Hostler, J Zhou, MA Tortorici, RR Bies, JC Rittenberger, PE Empey, ... Drug metabolism and disposition 38 (5), 781-788, 2010 | 90 | 2010 |
| Hepatic cytochrome P-450 expression in tumor necrosis factor-α receptor (p55/p75) knockout mice after endotoxin administration GW Warren, SM Poloyac, DS Gary, MP Mattson, RA Blouin Journal of Pharmacology and Experimental Therapeutics 288 (3), 945-950, 1999 | 87 | 1999 |
| Protective effect of the 20-HETE inhibitor HET0016 on brain damage after temporary focal ischemia SM Poloyac, Y Zhang, RR Bies, PM Kochanek, SH Graham Journal of Cerebral Blood Flow & Metabolism 26 (12), 1551-1561, 2006 | 82 | 2006 |
| Modulation of brain cation-Cl− cotransport via the SPAK kinase inhibitor ZT-1a J Zhang, MIH Bhuiyan, T Zhang, JK Karimy, Z Wu, VM Fiesler, J Zhang, ... Nature communications 11 (1), 78, 2020 | 81 | 2020 |
| Pre-clinical testing of therapies for traumatic brain injury DS DeWitt, BE Hawkins, CE Dixon, PM Kochanek, W Armstead, CR Bass, ... Journal of neurotrauma 35 (23), 2737-2754, 2018 | 77 | 2018 |
| Levetiracetam treatment in traumatic brain injury: operation brain trauma therapy M Browning, DA Shear, HM Bramlett, CE Dixon, S Mondello, KE Schmid, ... Journal of neurotrauma 33 (6), 581-594, 2016 | 76 | 2016 |
| Role of endothelin-1 in human aneurysmal subarachnoid hemorrhage: associations with vasospasm and delayed cerebral ischemia BP Thampatty, PR Sherwood, MJ Gallek, EA Crago, D Ren, AJ Hricik, ... Neurocritical care 15, 19-27, 2011 | 74 | 2011 |
| Endothelin-1 is increased in cerebrospinal fluid and associated with unfavorable outcomes in children after severe traumatic brain injury R Salonia, PE Empey, SM Poloyac, SR Wisniewski, M Klamerus, ... Journal of neurotrauma 27 (10), 1819-1825, 2010 | 70 | 2010 |
