| Illuminating protein space with a programmable generative model JB Ingraham, M Baranov, Z Costello, KW Barber, W Wang, A Ismail, ... Nature 623 (7989), 1070-1078, 2023 | 210 | 2023 |
| Molecular basis for the N-terminal bromodomain-and-extra-terminal-family selectivity of a dual kinase–bromodomain inhibitor A Divakaran, SK Talluri, AM Ayoub, NK Mishra, H Cui, JC Widen, ... Journal of medicinal chemistry 61 (20), 9316-9334, 2018 | 70 | 2018 |
| Cryo-EM structure of the human MLL1 core complex bound to the nucleosome SH Park, A Ayoub, YT Lee, J Xu, H Kim, W Zheng, B Zhang, L Sha, S An, ... Nature communications 10 (1), 5540, 2019 | 58 | 2019 |
| BET bromodomain inhibitors with one-step synthesis discovered from virtual screen AM Ayoub, LML Hawk, RJ Herzig, J Jiang, AJ Wisniewski, CT Gee, ... Journal of medicinal chemistry 60 (12), 4805-4817, 2017 | 48 | 2017 |
| Inhibiting APOBEC3 activity with single-stranded DNA containing 2′-deoxyzebularine analogues MV Kvach, FM Barzak, S Harjes, HAM Schares, GB Jameson, AM Ayoub, ... Biochemistry 58 (5), 391-400, 2018 | 44 | 2018 |
| New contributions to the phylogeny of the ciliate class Heterotrichea (Protista, Ciliophora): analyses at family-genus level and new evolutionary hypotheses Y Chi, X Chen, Y Li, C Wang, T Zhang, A Ayoub, A Warren, W Song, ... Science China Life Sciences 64, 606-620, 2021 | 39 | 2021 |
| Mechanism for DPY30 and ASH2L intrinsically disordered regions to modulate the MLL/SET1 activity on chromatin YT Lee, A Ayoub, SH Park, L Sha, J Xu, F Mao, W Zheng, Y Zhang, ... Nature communications 12 (1), 2953, 2021 | 28 | 2021 |
| Insights on the regulation of the MLL/SET1 family histone methyltransferases L Sha, A Ayoub, US Cho, Y Dou Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1863 (7), 194561, 2020 | 27 | 2020 |
| Design, synthesis, and characterization of a fluorescence polarization pan-BET bromodomain probe CN Paulson, X Guan, AM Ayoub, A Chan, RM Karim, WCK Pomerantz, ... ACS Medicinal Chemistry Letters 9 (12), 1223-1229, 2018 | 13 | 2018 |
| Regulation of MLL1 methyltransferase activity in two distinct nucleosome binding modes A Ayoub, SH Park, YT Lee, US Cho, Y Dou Biochemistry 61 (1), 1-9, 2021 | 9 | 2021 |
| Alternative mechanisms for DNA engagement by BET bromodomain-containing proteins P Kalra, H Zahid, A Ayoub, Y Dou, WCK Pomerantz Biochemistry 61 (13), 1260-1272, 2022 | 4 | 2022 |
| Cryo-EM structure of the human Mixed Lineage Leukemia-1 complex bound to the nucleosome SH Park, A Ayoub, YT Lee, J Xu, H Kim, W Zhang, B Zhang, S An, ... bioRxiv, 737478, 2019 | 2 | 2019 |
| Structural and Biochemical Mechanisms of MLL1 Activation on Chromatin A Ayoub | | 2022 |
| MLL1 Methyltransferase Activity is Regulated by Distinct Nucleosome Binding Modes A Ayoub, SH Park, YT Lee, US Cho, Y Dou bioRxiv, 2021.04. 13.439652, 2021 | | 2021 |
| Cryo-EM structure of the human MLL1 core complex bound to the nucleosome (vol 13, pg 251, 2019) SH Park, A Ayoub, YT Lee, J Xu, H Kim, W Zheng, B Zhang, L Sha, S An, ... NATURE COMMUNICATIONS 11 (1), 2020 | | 2020 |
| Publisher Correction: Cryo-EM structure of the human MLL1 core complex bound to the nucleosome SH Park, A Ayoub, YT Lee, J Xu, H Kim, W Zheng, B Zhang, L Sha, S An, ... Nature Communications 11, 2020 | | 2020 |
| Discovery of allosteric inhibitors of NF-kappa B inducing kinase (NIK) J Tang, O Demir, G Chan, A Ayoub, R Amaro, D Harki ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 258, 2019 | | 2019 |
| Dual kinase-bromodomain inhibition of Brd4 and p38a using trisubstituted-imidazoles A Divakaran, S Talluri, A Ayoub, N Mishra, J Widen, JY Zhu, N Berndt, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 255, 2018 | | 2018 |
| Chemical biology approaches to inhibition of epigenetic protein-protein interactions between histones and bromodomains L Hawk, A Ayoub, R Herzig, A Wisniewski, C Gee, H Hu, G Georg, T Ward, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 252, 2016 | | 2016 |
| Chemical biology approaches for inhibiting protein recognition of acetylated histones L Hawk, A Ayoub, R Herzig, A Wisniewski, C Gee, A Urick, H Hu, G Georg, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 252, 2016 | | 2016 |
