Synergistic bacterial compositions and methods of production and use thereof MR Henn, G Von Maltzahn, AM D'onofrio, KD Litcofsky, DA Berry, ... US Patent 9,028,841, 2015 | 353 | 2015 |
SER-109, an Oral Microbiome Therapy for Recurrent Clostridioides difficile Infection P Feuerstadt, TJ Louie, B Lashner, EEL Wang, L Diao, JA Bryant, M Sims, ... New England Journal of Medicine 386 (3), 220-229, 2022 | 350 | 2022 |
Synergistic bacterial compositions and methods of production and use thereof MR Henn, G Von Maltzahn, AM D'onofrio, KD Litcofsky, DA Berry, ... US Patent 8,906,668, 2014 | 323 | 2014 |
Synergistic bacterial compositions and methods of production and use thereof MR Henn, G Von Maltzahn, AM D'onofrio, KD Litcofsky, DA Berry, ... US Patent 9,533,014, 2017 | 208 | 2017 |
SER-109, an Investigational Microbiome Drug to Reduce Recurrence After Clostridioides difficile Infection: Lessons Learned From a Phase 2 Trial BH McGovern, CB Ford, MR Henn, DS Pardi, S Khanna, EL Hohmann, ... Clinical Infectious Diseases 72 (12), 2132-2140, 2021 | 140 | 2021 |
Iterative plug-and-play methodology for constructing and modifying synthetic gene networks KD Litcofsky, RB Afeyan, RJ Krom, AS Khalil, JJ Collins Nature methods 9 (11), 1077-1080, 2012 | 113 | 2012 |
Network-based microbial compositions and methods MR Henn, DN Cook, TK Ohsumi, MJL McKenzie, KD Litcofsky, H Zhang, ... US Patent 10,076,546, 2018 | 53 | 2018 |
Synergistic bacterial compositions and methods of production and use thereof MR Henn, G Von Maltzahn, AM D'onofrio, KD Litcofsky, DA Berry, ... US Patent App. 15/359,439, 2017 | 49 | 2017 |
Synergistic bacterial compositions and methods of production and use thereof MR Henn, KD Litcofsky, AM D'onofrio, TK Ohsumi, MJL McKenzie, ... US Patent 10,258,655, 2019 | 38 | 2019 |
Synergistic bacterial compositions and methods of production and use thereof MR Henn, G Von Maltzahn, AM D'onofrio, KD Litcofsky, DA Berry, ... US Patent 10,864,235, 2020 | 16 | 2020 |
Compositions and methods NB Afeyan, MJL McKenzie, KD Litcofsky, DN Cook, MR Henn, ... US Patent 10,973,861, 2021 | 13 | 2021 |
1503. Engraftment of investigational microbiome drug, SER-262, in subjects receiving vancomycin is associated with reduced rates of recurrence after primary Clostridium … C Ford, K Litcofsky, B McGovern, D Pardi, R Nathan, V Hansen, ... Open Forum Infectious Diseases 6 (Supplement_2), S547-S548, 2019 | 10 | 2019 |
Network-based microbial compositions and methods MR Henn, DN Cook, TK Ohsumi, MJL McKenzie, KD Litcofsky, H Zhang, ... US Patent 10,881,696, 2021 | 9 | 2021 |
Network-based microbial compositions and methods MR Henn, DN Cook, TK Ohsumi, MJL McKenzie, KD Litcofsky, H Zhang, ... US Patent 11,666,612, 2023 | 5 | 2023 |
Synergistic bacterial compositions and methods of production and use thereof MR Henn, G Von Maltzahn, AM D'onofrio, KD Litcofsky, DA Berry, ... US Patent 11,458,174, 2022 | 5 | 2022 |
Synergistic bacterial compositions and methods of production and use thereof MR Henn, G Von Maltzahn, AM D'onofrio, KD Litcofsky, DA Berry, ... US Patent 11,389,490, 2022 | 5 | 2022 |
Designed bacterial compositions J Button, D Cook, H Matthew, MJL McKenzie, K Litcofsky, A Martinez, ... US Patent App. 15/778,095, 2019 | 5 | 2019 |
623–Ser-287, an investigational microbiome therapeutic, induces widespread transcriptional changes related to clinical remission in a placebo-controlled, double-blind … L Diao, MC Nnamani, E OBrien, C Desjardins, A Martinez, S Simmons, ... Gastroenterology 156 (6), S-130, 2019 | 5 | 2019 |
1641. Treatment of Recurrent Clostridium difficile Infection With SER-109 Reduces Gastrointestinal Carriage of Antimicrobial Resistance Genes C Ford, M Henn, J Bryant, L Diao, J Wortman, A Tomlinson, K Litcofsky, ... Open Forum Infectious Diseases 5 (suppl_1), S46-S47, 2018 | 5 | 2018 |
Synergistic bacterial compositions and methods of production and use thereof MR Henn, KD Litcofsky, AM D'onofrio, TK Ohsumi, MJL McKenzie, ... US Patent 11,266,699, 2022 | 4 | 2022 |