Tau interacts with the C-terminal region of α-synuclein, promoting formation of toxic aggregates with distinct molecular conformations AKR Dasari, R Kayed, S Wi, KH Lim Biochemistry 58 (25), 2814-2821, 2019 | 78 | 2019 |
Transthyretin aggregation pathway toward the formation of distinct cytotoxic oligomers AKR Dasari, RM Hughes, S Wi, I Hung, Z Gan, JW Kelly, KH Lim Scientific reports 9 (1), 33, 2019 | 53 | 2019 |
Structural changes associated with transthyretin misfolding and amyloid formation revealed by solution and solid-state NMR KH Lim, AKR Dasari, I Hung, Z Gan, JW Kelly, DE Wemmer Biochemistry 55 (13), 1941-1944, 2016 | 48 | 2016 |
Solid-state NMR studies reveal native-like β-sheet structures in transthyretin amyloid KH Lim, AKR Dasari, I Hung, Z Gan, JW Kelly, PE Wright, DE Wemmer Biochemistry 55 (37), 5272-5278, 2016 | 38 | 2016 |
Pathogenic mutations induce partial structural changes in the native β-sheet structure of transthyretin and accelerate aggregation KH Lim, AKR Dasari, R Ma, I Hung, Z Gan, JW Kelly, MC Fitzgerald Biochemistry 56 (36), 4808-4818, 2017 | 29 | 2017 |
Disruption of the CD loop by enzymatic cleavage promotes the formation of toxic transthyretin oligomers through a common transthyretin misfolding pathway AKR Dasari, J Arreola, B Michael, RG Griffin, JW Kelly, KH Lim Biochemistry 59 (25), 2319-2327, 2020 | 23 | 2020 |
Two distinct aggregation pathways in transthyretin misfolding and amyloid formation AKR Dasari, I Hung, Z Gan, KH Lim Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1867 (3), 344-349, 2019 | 16 | 2019 |
Tau induces formation of α-synuclein filaments with distinct molecular conformations A Hojjatian, AKR Dasari, U Sengupta, D Taylor, N Daneshparvar, ... Biochemical and biophysical research communications 554, 145-150, 2021 | 15 | 2021 |
Covalent and non-covalent strategies for the immobilization of Tobacco Etch Virus protease (TEVp) on superparamagnetic nanoparticles JL Norris, T Patel, AKR Dasari, TA Cope, KH Lim, RM Hughes Journal of Biotechnology 322, 1-9, 2020 | 11 | 2020 |
Structural characterization of cardiac ex vivo transthyretin amyloid: insight into the transthyretin misfolding pathway in vivo AKR Dasari, I Hung, B Michael, Z Gan, JW Kelly, LH Connors, RG Griffin, ... Biochemistry 59 (19), 1800-1803, 2020 | 11 | 2020 |
Untwisted α-synuclein Filaments formed in the Presence of Lipid Vesicles AKR Dasari, L Dillard, S Yi, E Viverette, A Hojjatian, U Sengupta, R Kayed, ... Biochemistry 61 (17), 1766-1773, 2022 | 7 | 2022 |
Distinct cryo-EM Structure of α-synuclein Filaments derived by Tau A Hojjatian, AKR Dasari, U Sengupta, D Taylor, N Daneshparvar, ... biorxiv, 2020.12. 31.424989, 2021 | 6 | 2021 |
Toxic Misfolded transthyretin oligomers with different molecular conformations formed through distinct oligomerization pathways AKR Dasari, S Yi, MF Coats, S Wi, KH Lim Biochemistry 61 (21), 2358-2365, 2022 | 5 | 2022 |
Characterization of α-synuclein oligomers formed in the presence of lipid vesicles AKR Dasari, U Sengupta, E Viverette, MJ Borgnia, R Kayed, KH Lim Biochemistry and Biophysics Reports 38, 101687, 2024 | | 2024 |
Identification of the interfacial regions in misfolded transthyretin oligomers AKR Dasari, MF Coats, AB Ali, KH Lim Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics, 141027, 2024 | | 2024 |
CD and Solid-State NMR Studies of Low-Order Oligomers of Transthyretin AKR Dasari, KH Lim Protein Aggregation: Methods and Protocols, 311-320, 2022 | | 2022 |
Tau Induces Formation of α-synuclein Filaments with Distinct Molecular Conformations AKR Dasari, KH Lim, A Hojjatian, U Sengupta, D Taylor, N Daneshparvar, ... | | 2021 |
Alpha-synuclein Fibrils Structure Determination in the Presence of Tau Using CryoEM A Hojjatian, A Dasari, D Taylor, N Daneshparvar, FA Yeganeh, K Taylor Microscopy and Microanalysis 26 (S2), 1302-1304, 2020 | | 2020 |
Single Particle Cryo-EM Structure of Alpha-Synuclein Fibrils Interacting with Tau A Hojjatian, AKR Dasari, D Taylor, N Daneshparvar, FAA Yeganeh, ... Biophysical Journal 118 (3), 41a, 2020 | | 2020 |
Elucidating the Mechanisms of Transthyretin Aggregation in Transthyretin Amyloidosis AKR Dasari East Carolina University, 2018 | | 2018 |