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Ekene Nweke, PhD
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Downregulation of the let‑7 family of microRNAs may promote insulin receptor/insulin‑like growth factor signalling pathways in pancreatic ductal adenocarcinoma
EE Nweke, M Brand
Oncology Letters 20 (3), 2613-2620, 2020
172020
SWATH-MS based proteomic profiling of pancreatic ductal adenocarcinoma tumours reveals the interplay between the extracellular matrix and related intracellular pathways
EE Nweke, P Naicker, S Aron, S Stoychev, J Devar, DL Tabb, ...
PLoS One 15 (10), e0240453, 2020
152020
Role of different immune cells and metabolic pathways in modulating the immune response in pancreatic cancer
N Elebo, P Fru, J Omoshoro‑Jones, G Patrick Candy, EE Nweke
Molecular Medicine Reports 22 (6), 4981-4991, 2020
132020
Transient expression of interleukin-21 in the second hit of acute pancreatitis may potentiate immune paresis in severe acute pancreatitis
JE Thomson, EE Nweke, M Brand, M Nel, GP Candy, PN Fonteh
Pancreas 48 (1), 107-112, 2019
122019
Targeting growth factor signaling pathways in pancreatic cancer: towards inhibiting chemoresistance
N Xelwa, GP Candy, J Devar, J Omoshoro-Jones, M Smith, EE Nweke
Frontiers in Oncology 11, 683788, 2021
112021
The Drosophila RetinoblastomaBinding Protein 6 Family Member Has Two Isoformsand Is Potentially Involved in Embryonic Patterning
R Hull, B Oosthuysen, UF Cajee, L Mokgohloa, E Nweke, RJ Antunes, ...
International journal of molecular sciences 16 (5), 10242-10266, 2015
112015
Increased expression of plakoglobin is associated with upregulated MAPK and PI3K/AKT signalling pathways in early resectable pancreatic ductal adenocarcinoma
E Nweke, M Ntwasa, M Brand, J Devar, M Smith, G Candy
Oncology letters 19 (6), 4133-4141, 2020
102020
Serum metabolomic and lipoprotein profiling of pancreatic ductal adenocarcinoma patients of african ancestry
N Elebo, J Omoshoro-Jones, PN Fru, J Devar, C De Wet van Zyl, ...
Metabolites 11 (10), 663, 2021
92021
Drug sensitivity and drug repurposing platform for cancer precision medicine
EE Nweke, DB Thimiri Govinda Raj
Cell biology and translational medicine, volume 12: Stem cells in …, 2021
92021
Immunotherapeutic strategies in pancreatic ductal adenocarcinoma (PDAC): current perspectives and future prospects
Z Nsingwane, G Candy, J Devar, J Omoshoro-Jones, M Smith, E Nweke
Molecular Biology Reports 47 (8), 6269-6280, 2020
82020
Targeting gallbladder cancer: a pathway based perspective
P Baichan, P Naicker, JWS Devar, M Smith, GP Candy, E Nweke
Molecular Biology Reports 47, 2361-2369, 2020
82020
Polyethyleneglycol-betulinic acid (PEG-BA) polymer-drug conjugate induces apoptosis and antioxidation in a biological model of pancreatic cancer
KS Mosiane, EE Nweke, M Balogun, PN Fru
Polymers 15 (2), 448, 2023
62023
Anti-cancer and immunomodulatory activity of a polyethylene glycol-betulinic acid conjugate on pancreatic cancer cells
PN Fru, EE Nweke, N Mthimkhulu, S Mvango, M Nel, LA Pilcher, ...
Life 11 (6), 462, 2021
62021
Proteomic analysis identifies dysregulated proteins and associated molecular pathways in a cohort of gallbladder cancer patients of African ancestry
P Baichan, P Naicker, TN Augustine, M Smith, G Candy, J Devar, ...
Clinical Proteomics 20 (1), 8, 2023
52023
Prospects of delivering natural compounds by polymer-drug conjugates in cancer therapeutics
N Mthimkhulu, KS Mosiane, EE Nweke, M Balogun, PN Fru
Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2022
52022
Development of insect cell line using CRISPR technology
EE Nweke, DBTG Raj
Progress in Molecular Biology and Translational Science 180, 1-20, 2021
52021
Differences in microbiome in rat models of cardiovascular disease
A Thiba, CU Umar, S Myende, E Nweke, K Rumbold, G Candy
South African Journal of Surgery 55 (2), 73-74, 2017
52017
Delineating intra-tumoral heterogeneity and tumor evolution in breast cancer using precision-based approaches
KR Xulu, EE Nweke, TN Augustine
Frontiers in Genetics 14, 1087432, 2023
42023
The retinoblastoma binding protein 6 family is essential for embryonic development and carcinogenesis
M Ntwasa, E Nweke, U Cajee
Journal of Cancer Research Forecast 1, 2018
32018
Complement protein levels decrease with tumour severity in pancreatic ductal adenocarcinoma
Z Nsingwane, N Elebo, N Mhlambi, J Devar, J Omoshoro-jones, M Smith, ...
HPB 24, S266, 2022
22022
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