| HIF‐1 is expressed in normoxic tissue and displays an organ‐specific regulation under systemic hypoxia DM Stroka, T Burkhardt, I Desbaillets, RH Wenger, DAH Neil, C Bauer, ... The FASEB Journal 15 (13), 2445-2453, 2001 | 940 | 2001 |
| The liver may act as a firewall mediating mutualism between the host and its gut commensal microbiota ML Balmer, E Slack, A De Gottardi, MAE Lawson, S Hapfelmeier, L Miele, ... Science translational medicine 6 (237), 237ra66-237ra66, 2014 | 467 | 2014 |
| A20 blocks endothelial cell activation through a NF-κB-dependent mechanism JT Cooper, DM Stroka, C Brostjan, A Palmetshofer, FH Bach, C Ferran Journal of Biological Chemistry 271 (30), 18068-18073, 1996 | 342 | 1996 |
| Interferon‐inducible expression of APOBEC3 editing enzymes in human hepatocytes and inhibition of hepatitis B virus replication M Bonvin, F Achermann, I Greeve, D Stroka, A Keogh, D Inderbitzin, ... Hepatology 43 (6), 1364-1374, 2006 | 316 | 2006 |
| Glucocorticoid-mediated repression of NFκB activity in endothelial cells does not involve induction of IκBα synthesis C Brostjan, J Anrather, V Csizmadia, D Stroka, M Soares, FH Bach, ... Journal of Biological Chemistry 271 (32), 19612-19616, 1996 | 253 | 1996 |
| The Met kinase inhibitor SU11274 exhibits a selective inhibition pattern toward different receptor mutated variants S Berthou, DM Aebersold, LS Schmidt, D Stroka, C Heigl, B Streit, ... Oncogene 23 (31), 5387-5393, 2004 | 239 | 2004 |
| Apoptosis in hypoxic human pancreatic islets correlates with HIF‐1α expression W Moritz, F Meier, D Stroka, M Giuliani, P Kugelmeier, PC Nett, ... The FASEB Journal 16 (7), 745-747, 2002 | 239 | 2002 |
| Bcl-2 and Bcl-XL serve an anti-inflammatory function in endothelial cells through inhibition of NF-κB AZ Badrichani, DM Stroka, G Bilbao, DT Curiel, FH Bach, C Ferran The Journal of clinical investigation 103 (4), 543-553, 1999 | 228 | 1999 |
| A20 Inhibits NF-κB Activation in Endothelial Cells Without Sensitizing to Tumor Necrosis Factor–Mediated Apoptosis C Ferran, DM Stroka, AZ Badrichani, JT Cooper, CJ Wrighton, M Soares, ... Blood, The Journal of the American Society of Hematology 91 (7), 2249-2258, 1998 | 196 | 1998 |
| Inhibition of SIRT1 impairs the accumulation and transcriptional activity of HIF-1α protein under hypoxic conditions A Laemmle, A Lechleiter, V Roh, C Schwarz, S Portmann, C Furer, ... PloS one 7 (3), e33433, 2012 | 173 | 2012 |
| Analysis of CD39/ATP diphosphohydrolase (ATPDase) expression in endothelial cells, platelets and leukocytes K Koziak, J Sévigny, SC Robson, JB Siegel, E Kaczmarek Thrombosis and haemostasis 82 (11), 1538-1544, 1999 | 165 | 1999 |
| TRAIL receptor–mediated JNK activation and Bim phosphorylation critically regulate Fas-mediated liver damage and lethality N Corazza, S Jakob, C Schaer, S Frese, A Keogh, D Stroka, D Kassahn, ... The Journal of clinical investigation 116 (9), 2493-2499, 2006 | 152 | 2006 |
| Antitumor Effect of SIRT1 Inhibition in Human HCC Tumor Models In Vitro and In Vivo S Portmann, R Fahrner, A Lechleiter, A Keogh, S Overney, A Laemmle, ... Molecular cancer therapeutics 12 (4), 499-508, 2013 | 133 | 2013 |
| Impaired liver regeneration in aged mice can be rescued by silencing Hippo core kinases MST1 and MST2 G Loforese, T Malinka, A Keogh, F Baier, C Simillion, M Montani, ... EMBO molecular medicine 9 (1), 46-60, 2017 | 118 | 2017 |
| Hypoxia aggravates non-alcoholic steatohepatitis in mice lacking hepatocellular PTEN AC Piguet, D Stroka, A Zimmermann, JF Dufour Clinical science 118 (6), 401-410, 2010 | 118 | 2010 |
| Extracellular ATP and ADP activate transcription factor NF-κB and induce endothelial cell apoptosis M von Albertini, A Palmetshofer, E Kaczmarek, K Koziak, D Stroka, ... Biochemical and biophysical research communications 248 (3), 822-829, 1998 | 118 | 1998 |
| Epolones induce erythropoietin expression via hypoxia-inducible factor-1α activation RM Wanner, P Spielmann, DM Stroka, G Camenisch, I Camenisch, ... Blood, The Journal of the American Society of Hematology 96 (4), 1558-1565, 2000 | 113 | 2000 |
| Inhibition of mTOR in combination with doxorubicin in an experimental model of hepatocellular carcinoma AC Piguet, D Semela, A Keogh, L Wilkens, D Stroka, C Stoupis, ... Journal of hepatology 49 (1), 78-87, 2008 | 108 | 2008 |
| Stimulation of AMP-activated protein kinase is essential for the induction of drug metabolizing enzymes by phenobarbital in human and mouse liver F Rencurel, M Foretz, MR Kaufmann, D Stroka, R Looser, I Leclerc, ... Molecular pharmacology 70 (6), 1925-1934, 2006 | 107 | 2006 |
| Attenuation of HIF-1 DNA-binding activity limits hypoxia-inducible endothelin-1 expression G Camenisch, D Stroka, M Gassmann, R Wenger Pflügers Archiv 443, 240-249, 2001 | 103 | 2001 |
