Sulforaphane, a dietary component of broccoli/broccoli sprouts, inhibits breast cancer stem cells Y Li, T Zhang, H Korkaya, S Liu, HF Lee, B Newman, Y Yu, SG Clouthier, ... Clinical Cancer Research 16 (9), 2580-2590, 2010 | 663 | 2010 |
A novel Hsp90 inhibitor to disrupt Hsp90/Cdc37 complex against pancreatic cancer cells T Zhang, A Hamza, X Cao, B Wang, S Yu, CG Zhan, D Sun Molecular cancer therapeutics 7 (1), 162-170, 2008 | 436 | 2008 |
Withaferin A targets heat shock protein 90 in pancreatic cancer cells Y Yu, A Hamza, T Zhang, M Gu, P Zou, B Newman, Y Li, AAL Gunatilaka, ... Biochemical pharmacology 79 (4), 542-551, 2010 | 348 | 2010 |
A Potent and Orally Active Antagonist (SM-406/AT-406) of Multiple Inhibitor of Apoptosis Proteins (IAPs) in Clinical Development for Cancer Treatment Q Cai, H Sun, Y Peng, J Lu, Z Nikolovska-Coleska, D McEachern, L Liu, ... Journal of medicinal chemistry, 2011 | 295 | 2011 |
New developments in Hsp90 inhibitors as anti-cancer therapeutics: mechanisms, clinical perspective and more potential Y Li, T Zhang, SJ Schwartz, D Sun Drug Resistance Updates 12 (1-2), 17-27, 2009 | 244 | 2009 |
Targeting cancer stem cells by curcumin and clinical applications Y Li, T Zhang Cancer letters 346 (2), 197-205, 2014 | 222 | 2014 |
A Novel Small-Molecule Inhibitor of Mcl-1 Blocks Pancreatic Cancer Growth In Vitro and In Vivo F Abulwerdi, C Liao, M Liu, AS Azmi, A Aboukameel, ASA Mady, ... Molecular cancer therapeutics 13 (3), 565-575, 2014 | 217 | 2014 |
Characterization of celastrol to inhibit hsp90 and cdc37 interaction T Zhang, Y Li, Y Yu, P Zou, Y Jiang, D Sun Journal of Biological Chemistry 284 (51), 35381-35389, 2009 | 214 | 2009 |
Drug transporter and cytochrome P450 mRNA expression in human ocular barriers: implications for ocular drug disposition T Zhang, CD Xiang, D Gale, S Carreiro, EY Wu, EY Zhang Drug Metabolism and Disposition 36 (7), 1300-1307, 2008 | 180 | 2008 |
Sulforaphane enhances the anticancer activity of taxanes against triple negative breast cancer by killing cancer stem cells JP Burnett, G Lim, Y Li, RB Shah, R Lim, HJ Paholak, SP McDermott, ... Cancer Letters 394, 52-64, 2017 | 131 | 2017 |
(−)-Epigallocatechin-3-gallate inhibits Hsp90 function by impairing Hsp90 association with cochaperones in pancreatic cancer cell line Mia Paca-2 Y Li, T Zhang, Y Jiang, HF Lee, SJ Schwartz, D Sun Molecular pharmaceutics 6 (4), 1152-1159, 2009 | 113 | 2009 |
Synergistic antipancreatic tumor effect by simultaneously targeting hypoxic cancer cells with HSP90 inhibitor and glycolysis inhibitor X Cao, M Bloomston, T Zhang, WL Frankel, G Jia, B Wang, NC Hall, ... Clinical Cancer Research 14 (6), 1831-1839, 2008 | 104 | 2008 |
Targeting cancer stem cells with sulforaphane, a dietary component from broccoli and broccoli sprouts Y Li, T Zhang Future oncology 9 (8), 1097-1103, 2013 | 86 | 2013 |
Combination of chemotherapy and cancer stem cell targeting agents: Preclinical and clinical studies Y Li, K Atkinson, T Zhang Cancer letters 396, 103-109, 2017 | 82 | 2017 |
Flavonoids and colorectal cancer prevention Y Li, T Zhang, GY Chen Antioxidants 7 (12), 187, 2018 | 76 | 2018 |
Sulforaphane inhibits pancreatic cancer through disrupting Hsp90–p50< sup> Cdc37</sup> complex and direct interactions with amino acids residues of Hsp90 Y Li, GE Karagöz, YH Seo, T Zhang, Y Jiang, Y Yu, A Duarte, SJ Schwartz, ... The Journal of Nutritional Biochemistry, 2012 | 74* | 2012 |
Characterization of human corneal epithelial cell model as a surrogate for corneal permeability assessment: metabolism and transport CD Xiang, M Batugo, DC Gale, T Zhang, J Ye, C Li, S Zhou, EY Wu, ... Drug Metabolism and Disposition 37 (5), 992-998, 2009 | 69 | 2009 |
The effects of pharmaceutical excipients on gastrointestinal tract metabolic enzymes and transporters—an update W Zhang, Y Li, P Zou, M Wu, Z Zhang, T Zhang The AAPS journal 18, 830-843, 2016 | 68 | 2016 |
EGY1 plays a role in regulation of endodermal plastid size and number that are involved in ethylene-dependent gravitropism of light-grown Arabidopsis hypocotyls D Guo, X Gao, H Li, T Zhang, G Chen, P Huang, L An, N Li Plant Molecular Biology 66, 345-360, 2008 | 64 | 2008 |
Sulforaphane Potentiates the Efficacy of 17-Allylamino 17-Demethoxygeldanamycin Against Pancreatic Cancer Through Enhanced Abrogation of Hsp90 Chaperone Function Y Li, T Zhang, SJ Schwartz, D Sun Nutrition and Cancer 63 (7), 1151-1159, 2011 | 56 | 2011 |