| Elective surgery cancellations due to the COVID-19 pandemic: global predictive modelling to inform surgical recovery plans Journal of British Surgery 107 (11), 1440-1449, 2020 | 1532 | 2020 |
| Mortality after surgery in Europe: a 7 day cohort study RM Pearse, RP Moreno, P Bauer, P Pelosi, P Metnitz, C Spies, B Vallet, ... The Lancet 380 (9847), 1059-1065, 2012 | 1453 | 2012 |
| Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy A Bierhaus, T Fleming, S Stoyanov, A Leffler, A Babes, C Neacsu, ... Nature medicine 18 (6), 926-933, 2012 | 560 | 2012 |
| Sensory neuron sodium channel Nav1.8 is essential for pain at low temperatures K Zimmermann, A Leffler, A Babes, CM Cendan, RW Carr, J Kobayashi, ... Nature 447 (7146), 856-859, 2007 | 491 | 2007 |
| Desensitization of capsaicin-activated currents in the vanilloid receptor TRPV1 is decreased by the cyclic AMP-dependent protein kinase pathway DP Mohapatra, C Nau Journal of biological chemistry 278 (50), 50080-50090, 2003 | 351 | 2003 |
| Regulation of Ca2+-dependent desensitization in the vanilloid receptor TRPV1 by calcineurin and cAMP-dependent protein kinase DP Mohapatra, C Nau Journal of Biological Chemistry 280 (14), 13424-13432, 2005 | 350 | 2005 |
| PKA/AKAP/VR-1 module: A common link of Gs-mediated signaling to thermal hyperalgesia PK Rathee, C Distler, O Obreja, W Neuhuber, GK Wang, SY Wang, C Nau, ... Journal of Neuroscience 22 (11), 4740-4745, 2002 | 309 | 2002 |
| The vanilloid receptor TRPV1 is activated and sensitized by local anesthetics in rodent sensory neurons A Leffler, MJ Fischer, D Rehner, S Kienel, K Kistner, SK Sauer, NR Gavva, ... The Journal of clinical investigation 118 (2), 763-776, 2008 | 244 | 2008 |
| TRPA1 and substance P mediate colitis in mice MA Engel, A Leffler, F Niedermirtl, A Babes, K Zimmermann, MR Filipović, ... Gastroenterology 141 (4), 1346-1358, 2011 | 238 | 2011 |
| Interactions of Local Anesthetics with Voltage-gated Na+ Channels C Nau, GK Wang The Journal of membrane biology 201, 1-8, 2004 | 236 | 2004 |
| The surgical safety checklist and patient outcomes after surgery: a prospective observational cohort study, systematic review and meta-analysis TEF Abbott, T Ahmad, MK Phull, AJ Fowler, R Hewson, BM Biccard, ... British journal of anaesthesia 120 (1), 146-155, 2018 | 169 | 2018 |
| The general anesthetic propofol excites nociceptors by activating TRPV1 and TRPA1 rather than GABAA receptors MJM Fischer, A Leffler, F Niedermirtl, K Kistner, M Eberhardt, PW Reeh, ... Journal of Biological Chemistry 285 (45), 34781-34792, 2010 | 141 | 2010 |
| Local Anesthetic-like Inhibition of Voltage-gated Na+Channels by the Partial μ-opioid Receptor Agonist Buprenorphine A Leffler, G Frank, K Kistner, F Niedermirtl, W Koppert, PW Reeh, C Nau The Journal of the American Society of Anesthesiologists 116 (6), 1335-1346, 2012 | 135 | 2012 |
| Residues in Na+ channel D3-S6 segment modulate both batrachotoxin and local anesthetic affinities SY Wang, C Nau, GK Wang Biophysical Journal 79 (3), 1379-1387, 2000 | 129 | 2000 |
| Block of human heart hH1 sodium channels by amitriptyline C Nau, M Seaver, SY Wang, GK Wang Journal of Pharmacology and Experimental Therapeutics 292 (3), 1015-1023, 2000 | 127 | 2000 |
| Point mutations at N434 in D1-S6 of μ1 Na+ channels modulate binding affinity and stereoselectivity of local anesthetic enantiomers C Nau, SY Wang, GR Strichartz, GK Wang Molecular pharmacology 56 (2), 404-413, 1999 | 122 | 1999 |
| Activation of TRPA1 by membrane permeable local anesthetics A Leffler, A Lattrell, S Kronewald, F Niedermirtl, C Nau Molecular pain 7, 1744-8069-7-62, 2011 | 121 | 2011 |
| Drug chirality in anesthesia RB Weiskopf, C Nau, GR Strichartz The Journal of the American Society of Anesthesiologists 97 (2), 497-502, 2002 | 119 | 2002 |
| Potency of Bupivacaine Stereoisomers Tested In Vitro and In Vivo: Biochemical, Electrophysiological, and Neurobehavioral Studies M Vladimirov, C Nau, WM Mok, G Strichartz The Journal of the American Society of Anesthesiologists 93 (3), 744-755, 2000 | 111 | 2000 |
| A high‐threshold heat‐activated channel in cultured rat dorsal root ganglion neurons resembles TRPV2 and is blocked by gadolinium A Leffler, RM Linte, C Nau, P Reeh, A Babes European Journal of Neuroscience 26 (1), 12-22, 2007 | 105 | 2007 |
