| Epigenetic regulation of HIV-1 latency by cytosine methylation SE Kauder, A Bosque, A Lindqvist, V Planelles, E Verdin PLoS pathogens 5 (6), e1000495, 2009 | 471 | 2009 |
| An in-depth comparison of latent HIV-1 reactivation in multiple cell model systems and resting CD4+ T cells from aviremic patients CA Spina, J Anderson, NM Archin, A Bosque, J Chan, M Famiglietti, ... PLoS pathogens 9 (12), e1003834, 2013 | 449 | 2013 |
| Induction of HIV-1 latency and reactivation in primary memory CD4+ T cells A Bosque, V Planelles Blood, The Journal of the American Society of Hematology 113 (1), 58-65, 2009 | 405 | 2009 |
| Involvement of APO2 ligand/TRAIL in activation‐induced death of Jurkat and human peripheral blood T cells MJ Martínez‐Lorenzo, MA Alava, S Gamen, KJ Kim, A Chuntharapai, ... European journal of immunology 28 (9), 2714-2725, 1998 | 271 | 1998 |
| Homeostatic proliferation fails to efficiently reactivate HIV-1 latently infected central memory CD4+ T cells A Bosque, M Famiglietti, AS Weyrich, C Goulston, V Planelles PLoS pathogens 7 (10), e1002288, 2011 | 216 | 2011 |
| Apoptotic pathways are selectively activated by granzyme A and/or granzyme B in CTL-mediated target cell lysis J Pardo, A Bosque, R Brehm, R Wallich, J Naval, A Müllbacher, A Anel, ... The Journal of cell biology 167 (3), 457-468, 2004 | 208 | 2004 |
| An HIV-encoded antisense long noncoding RNA epigenetically regulates viral transcription S Saayman, A Ackley, AMW Turner, M Famiglietti, A Bosque, M Clemson, ... Molecular Therapy 22 (6), 1164-1175, 2014 | 196 | 2014 |
| Latent HIV reservoirs exhibit inherent resistance to elimination by CD8+ T cells SH Huang, Y Ren, AS Thomas, D Chan, S Mueller, AR Ward, S Patel, ... The Journal of clinical investigation 128 (2), 876-889, 2018 | 190 | 2018 |
| HIV-1 Vpr Triggers Natural Killer Cell–Mediated Lysis of Infected Cells through Activation of the ATR-Mediated DNA Damage Response J Ward, Z Davis, J DeHart, E Zimmerman, A Bosque, E Brunetta, D Mavilio, ... PLoS pathogens 5 (10), e1000613, 2009 | 152 | 2009 |
| Reactivation of latent HIV-1 in central memory CD4+T cells through TLR-1/2 stimulation CL Novis, NM Archin, MJ Buzon, E Verdin, JL Round, M Lichterfeld, ... Retrovirology 10, 1-15, 2013 | 148 | 2013 |
| BIRC2/cIAP1 is a negative regulator of HIV-1 transcription and can be targeted by Smac mimetics to promote reversal of viral latency L Pache, MS Dutra, AM Spivak, JM Marlett, JP Murry, Y Hwang, ... Cell host & microbe 18 (3), 345-353, 2015 | 145 | 2015 |
| A homozygous Fas ligand gene mutation in a patient causes a new type of autoimmune lymphoproliferative syndrome M Del-Rey, J Ruiz-Contreras, A Bosque, S Calleja, J Gomez-Rial, ... Blood 108 (4), 1306-1312, 2006 | 145 | 2006 |
| Cyclin T1 and CDK9 T-Loop Phosphorylation Are Downregulated during Establishment of HIV-1 Latency in Primary Resting Memory CD4+ T Cells S Budhiraja, M Famiglietti, A Bosque, V Planelles, AP Rice Journal of virology 87 (2), 1211-1220, 2013 | 129 | 2013 |
| Studies of HIV-1 latency in an ex vivo model that uses primary central memory T cells A Bosque, V Planelles Methods 53 (1), 54-61, 2011 | 124 | 2011 |
| HIV latency and integration site placement in five cell-based models S Sherrill-Mix, MK Lewinski, M Famiglietti, A Bosque, N Malani, ... Retrovirology 10, 1-14, 2013 | 119 | 2013 |
| Ruxolitinib and Tofacitinib Are Potent and Selective Inhibitors of HIV-1 Replication and Virus Reactivation In Vitro C Gavegnano, M Detorio, C Montero, A Bosque, V Planelles, RF Schinazi Antimicrobial agents and chemotherapy 58 (4), 1977-1986, 2014 | 113 | 2014 |
| Ex Vivo Bioactivity and HIV-1 Latency Reversal by Ingenol Dibenzoate and Panobinostat in Resting CD4+ T Cells from Aviremic Patients AM Spivak, A Bosque, AH Balch, D Smyth, L Martins, V Planelles Antimicrobial agents and chemotherapy 59 (10), 5984-5991, 2015 | 101 | 2015 |
| BCL-2 antagonism sensitizes cytotoxic T cell–resistant HIV reservoirs to elimination ex vivo Y Ren, SH Huang, S Patel, WDC Alberto, D Magat, D Ahimovic, ... The Journal of clinical investigation 130 (5), 2542-2559, 2020 | 91 | 2020 |
| Benzotriazoles reactivate latent HIV-1 through inactivation of STAT5 SUMOylation A Bosque, KA Nilson, AB Macedo, AM Spivak, NM Archin, ... Cell reports 18 (5), 1324-1334, 2017 | 88 | 2017 |
| Dual TLR2 and TLR7 agonists as HIV latency-reversing agents AB Macedo, CL Novis, CM De Assis, ES Sorensen, P Moszczynski, ... JCI insight 3 (19), 2018 | 78 | 2018 |
