| TOP1 inhibition therapy protects against SARS-CoV-2-induced lethal inflammation JSY Ho, BWY Mok, L Campisi, T Jordan, S Yildiz, S Parameswaran, ... Cell 184 (10), 2618-2632. e17, 2021 | 86 | 2021 |
| Antibiotics disrupt coordination between transcriptional and phenotypic stress responses in pathogenic bacteria PA Jensen, Z Zhu, T van Opijnen Cell reports 20 (7), 1705-1716, 2017 | 62 | 2017 |
| Unconventional viral gene expression mechanisms as therapeutic targets JSY Ho, Z Zhu, I Marazzi Nature 593 (7859), 362-371, 2021 | 40 | 2021 |
| Entropy of a bacterial stress response is a generalizable predictor for fitness and antibiotic sensitivity Z Zhu, D Surujon, JC Ortiz-Marquez, W Huo, RR Isberg, J Bento, ... Nature communications 11 (1), 4365, 2020 | 39 | 2020 |
| Hybrid gene origination creates human-virus chimeric proteins during infection JSY Ho, M Angel, Y Ma, E Sloan, G Wang, C Martinez-Romero, ... Cell 181 (7), 1502-1517. e23, 2020 | 39 | 2020 |
| The landscape of phenotypic and transcriptional responses to ciprofloxacin in Acinetobacter baumannii: acquired resistance alleles modulate drug-induced SOS response and … E Geisinger, G Vargas-Cuebas, NJ Mortman, S Syal, Y Dai, ... MBio 10 (3), 10.1128/mbio. 01127-19, 2019 | 35 | 2019 |
| The Transcriptional landscape of Streptococcus pneumoniae TIGR4 reveals a complex operon architecture and abundant riboregulation critical for growth and … I Warrier, N Ram-Mohan, Z Zhu, A Hazery, H Echlin, J Rosch, MM Meyer, ... PLoS pathogens 14 (12), e1007461, 2018 | 33 | 2018 |
| Virus-assisted directed evolution of enhanced suppressor tRNAs in mammalian cells D Jewel, RE Kelemen, RL Huang, Z Zhu, B Sundaresh, X Cao, K Malley, ... Nature methods 20 (1), 95-103, 2023 | 25 | 2023 |
| Three SpoA-domain proteins interact in the creation of the flagellar type III secretion system in Helicobacter pylori KH Lam, C Xue, K Sun, H Zhang, WWL Lam, Z Zhu, JTY Ng, WE Sause, ... Journal of Biological Chemistry 293 (36), 13961-13973, 2018 | 10 | 2018 |
| Antibiotics disrupt coordination between transcriptional and phenotypic stress responses in pathogenic bacteria. Cell Rep 20: 1705–1716 PA Jensen, Z Zhu, T van Opijnen | 10 | 2017 |
| Topoisomerase 1 inhibition therapy protects against SARS-CoV-2-induced inflammation and death in animal models JS Yuin Ho, B Wing-Yee Mok, L Campisi, T Jordan, S Yildiz, ... bioRxiv, 2020.12. 01.404483, 2020 | 8 | 2020 |
| A pangenomic perspective on the emergence, maintenance, and predictability of antibiotic resistance S Wood, K Zhu, D Surujon, F Rosconi, JC Ortiz-Marquez, T van Opijnen Pangenome, 169, 2020 | 7 | 2020 |
| Virus-assisted directed evolution of enhanced suppressor tRNAs in mammalian cells RE Kelemen, D Jewel, RL Huang, Z Zhu, X Cao, M Pasha, J Anthony, ... BioRxiv, 2022.01. 21.477302, 2022 | 5 | 2022 |
| Enhanced directed evolution in mammalian cells yields a hyperefficient pyrrolysyl tRNA for noncanonical amino acid mutagenesis D Jewel, RE Kelemen, RL Huang, Z Zhu, B Sundaresh, K Malley, Q Pham, ... Angewandte Chemie 136 (9), e202316428, 2024 | 4 | 2024 |
| The landscape of intrinsic and evolved fluoroquinolone resistance in Acinetobacter baumannii includes suppression of drug-induced prophage replication E Geisinger, G Vargas-Cuebas, NJ Mortman, S Syal, EL Wainwright, ... bioRxiv, 442681, 2018 | 3 | 2018 |
| Forecasting bacterial survival-success and adaptive evolution through multi-omics stress-response mapping, network analyses and machine learning Z Zhu, D Surujon, A Pavao, J Bento, T van Opijnen bioRxiv, 387910, 2018 | 3 | 2018 |
| Yersinia pseudotuberculosis doxycycline tolerance strategies include modulating expression of genes involved in cell permeability and tRNA modifications HS Alvarez-Manzo, RK Davidson, J Van Cauwelaert de Wyels, KL Cotten, ... PLoS pathogens 18 (5), e1010556, 2022 | 2 | 2022 |
| Network analysis links genome-wide phenotypic and transcriptional stress responses in a bacterial pathogen with a large pan-genome PA Jensen, Z Zhu, T van Opijnen BioRxiv, 071704, 2016 | 1 | 2016 |
| Forecasting bacterial survival-success and adaptive evolution through multiomics stress-response mapping and machine learning T Van Opijnen, Z Zhu, D Surujon US Patent 11,591,634, 2023 | | 2023 |
| The evolution of enhanced pyrrolysyl suppressor tRNAs in mammalian cells RE Kelemen, D Jewel, SD Levinson, X Cao, M Pasha, Z Zhu, J Anthony, ... New tools at the intersection of genetic code expansion, virus engineering …, 2019 | | 2019 |
