The role of itaconate in host defense and inflammation CG Peace, LAJ O’Neill The Journal of clinical investigation 132 (2), 2022 | 168 | 2022 |
Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages MC Runtsch, S Angiari, A Hooftman, R Wadhwa, Y Zhang, Y Zheng, ... Cell metabolism 34 (3), 487-501. e8, 2022 | 133 | 2022 |
Macrophage fumarate hydratase restrains mtRNA-mediated interferon production A Hooftman, CG Peace, DG Ryan, EA Day, M Yang, AF McGettrick, M Yin, ... Nature 615 (7952), 490-498, 2023 | 65 | 2023 |
Dimethyl fumarate and 4-octyl itaconate are anticoagulants that suppress Tissue Factor in macrophages via inhibition of Type I Interferon TAJ Ryan, A Hooftman, AM Rehill, MD Johansen, ECO Brien, ... Nature Communications 14 (1), 3513, 2023 | 15 | 2023 |
NLRP3, the inflammasome and COVID-19 infection M Yin, L Marrone, CG Peace, LAJ O’Neill QJM: An International Journal of Medicine 116 (7), 502-507, 2023 | 9 | 2023 |
Fumarate hydratase as a metabolic regulator of immunity CG Peace, SM O’Carroll, LAJ O’Neill Trends in Cell Biology, 2023 | 4 | 2023 |
Basic Mechanisms of Immunometabolites in Shaping the Immune Response DG Ryan, CG Peace, A Hooftman Journal of Innate Immunity 15 (1), 925-943, 2023 | 1 | 2023 |
Ironing Out Vaccine Efficacy CG Peace, LAJ O’Neill Med 2 (2), 113-114, 2021 | 1 | 2021 |
OC 55.2 Dimethyl Fumarate and 4-Octyl Itaconate are Anticoagulants that Suppress Tissue Factor in Macrophages Via Inhibition of Type I Interferon T Ryan, A Hooftman, A Rehill, M Johansen, E O’Brien, J Toller-Kawahisa, ... Research and Practice in Thrombosis and Haemostasis 7, 100502, 2023 | | 2023 |
Inflammatory mitochondrial nucleic acids as drivers of pathophysiology CG Peace, A Hooftman, DG Ryan Clinical and Translational Medicine 13 (9), 2023 | | 2023 |
Targeting fumarate hydratase promotes mitochondrial RNA-mediated interferon production A Hooftman, CG Peace, DG Ryan, EA Day, M Yang, AF McGettrick, M Yin, ... Nature 615 (7952), 490, 2023 | | 2023 |
Basic Mechanisms of Immunometabolites in Shaping the Immune DG Ryan, CG Peace, A Hooftman | | 2023 |
Publisher Correction: Dimethyl fumarate and 4-octyl itaconate are anticoagulants that suppress Tissue Factor in macrophages via inhibition of Type I Interferon TAJ Ryan, A Hooftman, AM Rehill, MD Johansen, EC O’Brien, ... nature communications 14, 2023 | | 2023 |