| Influence of polyethylene glycol chain length on the physicochemical and biological properties of poly (ethylene imine)-graft-poly (ethylene glycol) block copolymer/SiRNA … S Mao, M Neu, O Germershaus, O Merkel, J Sitterberg, U Bakowsky, ... Bioconjugate chemistry 17 (5), 1209-1218, 2006 | 394 | 2006 |
| Intranasal drug delivery: Opportunities and toxicologic challenges during drug development LA Keller, O Merkel, A Popp Drug delivery and translational research, 1-23, 2022 | 316 | 2022 |
| Applications of polymer micelles for imaging and drug delivery S Movassaghian, OM Merkel, VP Torchilin Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 7 (5 …, 2015 | 282 | 2015 |
| Stability of siRNA polyplexes from poly (ethylenimine) and poly (ethylenimine)-g-poly (ethylene glycol) under in vivo conditions: effects on pharmacokinetics and … OM Merkel, D Librizzi, A Pfestroff, T Schurrat, K Buyens, NN Sanders, ... Journal of Controlled Release 138 (2), 148-159, 2009 | 234 | 2009 |
| Controlled pulmonary drug and gene delivery using polymeric nano-carriers M Beck-Broichsitter, OM Merkel, T Kissel Journal of controlled release 161 (2), 214-224, 2012 | 232 | 2012 |
| Nonviral siRNA delivery to the lung: Investigation of PEG− PEI polyplexes and their in vivo performance OM Merkel, A Beyerle, D Librizzi, A Pfestroff, TM Behr, B Sproat, PJ Barth, ... Molecular pharmaceutics 6 (4), 1246-1260, 2009 | 222 | 2009 |
| In vivo pharmacokinetics, tissue distribution and underlying mechanisms of various PEI (–PEG)/siRNA complexes A Malek, O Merkel, L Fink, F Czubayko, T Kissel, A Aigner Toxicology and applied pharmacology 236 (1), 97-108, 2009 | 211 | 2009 |
| Fast degrading polyesters as siRNA nano-carriers for pulmonary gene therapy J Nguyen, TWJ Steele, O Merkel, R Reul, T Kissel Journal of controlled release 132 (3), 243-251, 2008 | 158 | 2008 |
| In vitro and in vivo complement activation and related anaphylactic effects associated with polyethylenimine and polyethylenimine-graft-poly (ethylene glycol) block copolymers OM Merkel, R Urbanics, P Bedőcs, Z Rozsnyay, L Rosivall, M Toth, ... Biomaterials 32 (21), 4936-4942, 2011 | 157 | 2011 |
| Nonviral pulmonary delivery of siRNA OM Merkel, T Kissel Accounts of chemical research 45 (7), 961-970, 2012 | 148 | 2012 |
| siRNA delivery to the lung: what's new? OM Merkel, I Rubinstein, T Kissel Advanced drug delivery reviews 75, 112-128, 2014 | 140 | 2014 |
| Immunogenicity of Cas9 protein A Mehta, OM Merkel Journal of pharmaceutical sciences 109 (1), 62-67, 2020 | 135 | 2020 |
| Triazine dendrimers as nonviral vectors for in vitro and in vivo RNAi: the effects of peripheral groups and core structure on biological activity OM Merkel, MA Mintzer, D Librizzi, O Samsonova, T Dicke, B Sproat, ... Molecular pharmaceutics 7 (4), 969-983, 2010 | 130 | 2010 |
| Lipids and polymers in pharmaceutical technology: Lifelong companions J Siepmann, A Faham, SD Clas, BJ Boyd, V Jannin, A Bernkop-Schnürch, ... International journal of pharmaceutics 558, 128-142, 2019 | 129 | 2019 |
| In vivo SPECT and real-time gamma camera imaging of biodistribution and pharmacokinetics of siRNA delivery using an optimized radiolabeling and purification procedure OM Merkel, D Librizzi, A Pfestroff, T Schurrat, M Béhé, T Kissel Bioconjugate chemistry 20 (1), 174-182, 2009 | 126 | 2009 |
| Targeted delivery of siRNA to activated T cells via transferrin-polyethylenimine (Tf-PEI) as a potential therapy of asthma Y Xie, NH Kim, V Nadithe, D Schalk, A Thakur, A Kılıç, LG Lum, ... Journal of Controlled Release 229, 120-129, 2016 | 115 | 2016 |
| Polymer-related off-target effects in non-viral siRNA delivery OM Merkel, A Beyerle, BM Beckmann, M Zheng, RK Hartmann, T Stöger, ... Biomaterials 32 (9), 2388-2398, 2011 | 115 | 2011 |
| Targeted Drug Delivery: Mannose and Mannose‐6‐Phosphate Receptor–Targeted Drug Delivery Systems and Their Application in Cancer Therapy (Adv. Healthcare Mater. 14/2018) E Dalle Vedove, G Costabile, OM Merkel Advanced Healthcare Materials 7 (14), 1870049, 2018 | 110* | 2018 |
| Triazine dendrimers as nonviral gene delivery systems: effects of molecular structure on biological activity OM Merkel, MA Mintzer, J Sitterberg, U Bakowsky, EE Simanek, T Kissel Bioconjugate chemistry 20 (9), 1799-1806, 2009 | 110 | 2009 |
| Enhancing in vivo circulation and siRNA delivery with biodegradable polyethylenimine-graft-polycaprolactone-block-poly (ethylene glycol) copolymers M Zheng, D Librizzi, A Kılıç, Y Liu, H Renz, OM Merkel, T Kissel Biomaterials 33 (27), 6551-6558, 2012 | 106 | 2012 |
Gabriella CostabileDepartment of Pharmacy, University of Napoli Federico II, Italy在 unina.it 的电子邮件经过验证
