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Olivia Merkel
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Influence of polyethylene glycol chain length on the physicochemical and biological properties of poly (ethylene imine)-graft-poly (ethylene glycol) block copolymer/SiRNA …
S Mao, M Neu, O Germershaus, O Merkel, J Sitterberg, U Bakowsky, ...
Bioconjugate chemistry 17 (5), 1209-1218, 2006
3942006
Intranasal drug delivery: Opportunities and toxicologic challenges during drug development
LA Keller, O Merkel, A Popp
Drug delivery and translational research, 1-23, 2022
3162022
Applications of polymer micelles for imaging and drug delivery
S Movassaghian, OM Merkel, VP Torchilin
Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 7 (5 …, 2015
2822015
Stability of siRNA polyplexes from poly (ethylenimine) and poly (ethylenimine)-g-poly (ethylene glycol) under in vivo conditions: effects on pharmacokinetics and …
OM Merkel, D Librizzi, A Pfestroff, T Schurrat, K Buyens, NN Sanders, ...
Journal of Controlled Release 138 (2), 148-159, 2009
2342009
Controlled pulmonary drug and gene delivery using polymeric nano-carriers
M Beck-Broichsitter, OM Merkel, T Kissel
Journal of controlled release 161 (2), 214-224, 2012
2322012
Nonviral siRNA delivery to the lung: Investigation of PEG− PEI polyplexes and their in vivo performance
OM Merkel, A Beyerle, D Librizzi, A Pfestroff, TM Behr, B Sproat, PJ Barth, ...
Molecular pharmaceutics 6 (4), 1246-1260, 2009
2222009
In vivo pharmacokinetics, tissue distribution and underlying mechanisms of various PEI (–PEG)/siRNA complexes
A Malek, O Merkel, L Fink, F Czubayko, T Kissel, A Aigner
Toxicology and applied pharmacology 236 (1), 97-108, 2009
2112009
Fast degrading polyesters as siRNA nano-carriers for pulmonary gene therapy
J Nguyen, TWJ Steele, O Merkel, R Reul, T Kissel
Journal of controlled release 132 (3), 243-251, 2008
1582008
In vitro and in vivo complement activation and related anaphylactic effects associated with polyethylenimine and polyethylenimine-graft-poly (ethylene glycol) block copolymers
OM Merkel, R Urbanics, P Bedőcs, Z Rozsnyay, L Rosivall, M Toth, ...
Biomaterials 32 (21), 4936-4942, 2011
1572011
Nonviral pulmonary delivery of siRNA
OM Merkel, T Kissel
Accounts of chemical research 45 (7), 961-970, 2012
1482012
siRNA delivery to the lung: what's new?
OM Merkel, I Rubinstein, T Kissel
Advanced drug delivery reviews 75, 112-128, 2014
1402014
Immunogenicity of Cas9 protein
A Mehta, OM Merkel
Journal of pharmaceutical sciences 109 (1), 62-67, 2020
1352020
Triazine dendrimers as nonviral vectors for in vitro and in vivo RNAi: the effects of peripheral groups and core structure on biological activity
OM Merkel, MA Mintzer, D Librizzi, O Samsonova, T Dicke, B Sproat, ...
Molecular pharmaceutics 7 (4), 969-983, 2010
1302010
Lipids and polymers in pharmaceutical technology: Lifelong companions
J Siepmann, A Faham, SD Clas, BJ Boyd, V Jannin, A Bernkop-Schnürch, ...
International journal of pharmaceutics 558, 128-142, 2019
1292019
In vivo SPECT and real-time gamma camera imaging of biodistribution and pharmacokinetics of siRNA delivery using an optimized radiolabeling and purification procedure
OM Merkel, D Librizzi, A Pfestroff, T Schurrat, M Béhé, T Kissel
Bioconjugate chemistry 20 (1), 174-182, 2009
1262009
Targeted delivery of siRNA to activated T cells via transferrin-polyethylenimine (Tf-PEI) as a potential therapy of asthma
Y Xie, NH Kim, V Nadithe, D Schalk, A Thakur, A Kılıç, LG Lum, ...
Journal of Controlled Release 229, 120-129, 2016
1152016
Polymer-related off-target effects in non-viral siRNA delivery
OM Merkel, A Beyerle, BM Beckmann, M Zheng, RK Hartmann, T Stöger, ...
Biomaterials 32 (9), 2388-2398, 2011
1152011
Targeted Drug Delivery: Mannose and Mannose‐6‐Phosphate Receptor–Targeted Drug Delivery Systems and Their Application in Cancer Therapy (Adv. Healthcare Mater. 14/2018)
E Dalle Vedove, G Costabile, OM Merkel
Advanced Healthcare Materials 7 (14), 1870049, 2018
110*2018
Triazine dendrimers as nonviral gene delivery systems: effects of molecular structure on biological activity
OM Merkel, MA Mintzer, J Sitterberg, U Bakowsky, EE Simanek, T Kissel
Bioconjugate chemistry 20 (9), 1799-1806, 2009
1102009
Enhancing in vivo circulation and siRNA delivery with biodegradable polyethylenimine-graft-polycaprolactone-block-poly (ethylene glycol) copolymers
M Zheng, D Librizzi, A Kılıç, Y Liu, H Renz, OM Merkel, T Kissel
Biomaterials 33 (27), 6551-6558, 2012
1062012
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