Pluripotent stem cell metabolism and mitochondria: beyond ATP JG Lees, DK Gardner, AJ Harvey Stem cells international 2017 (1), 2874283, 2017 | 85 | 2017 |
Fine-tuning the cardiac O-GlcNAcylation regulatory enzymes governs the functional and structural phenotype of the diabetic heart D Prakoso, SY Lim, JR Erickson, RS Wallace, JG Lees, M Tate, H Kiriazis, ... Cardiovascular research 118 (1), 212-225, 2022 | 59 | 2022 |
Sustained subcutaneous delivery of secretome of human cardiac stem cells promotes cardiac repair following myocardial infarction AR Kompa, DW Greening, AM Kong, PJ McMillan, H Fang, R Saxena, ... Cardiovascular Research 117 (3), 918-929, 2021 | 52 | 2021 |
Hydralazine protects the heart against acute ischaemia/reperfusion injury by inhibiting Drp1-mediated mitochondrial fission SB Kalkhoran, J Kriston-Vizi, S Hernandez-Resendiz, GE Crespo-Avilan, ... Cardiovascular Research 118 (1), 282-294, 2022 | 44 | 2022 |
Mitochondrial and glycolytic remodeling during nascent neural differentiation of human pluripotent stem cells JG Lees, DK Gardner, AJ Harvey Development 145 (20), dev168997, 2018 | 37 | 2018 |
Oxygen regulates human pluripotent stem cell metabolic flux JG Lees, TS Cliff, A Gammilonghi, JG Ryall, S Dalton, DK Gardner, ... Stem Cells International 2019 (1), 8195614, 2019 | 36 | 2019 |
Amorphous SiO2 nanoparticles promote cardiac dysfunction via the opening of the mitochondrial permeability transition pore in rat heart and human cardiomyocytes O Lozano, C Silva-Platas, H Chapoy-Villanueva, BE Pérez, JG Lees, ... Particle and Fibre Toxicology 17, 1-16, 2020 | 35 | 2020 |
Distinct profiles of human embryonic stem cell metabolism and mitochondria identified by oxygen JG Lees, J Rathjen, JR Sheedy, DK Gardner, AJ Harvey Reproduction 150 (4), 367-382, 2015 | 33 | 2015 |
A soft and ultrasensitive force sensing diaphragm for probing cardiac organoids instantaneously and wirelessly Q Lyu, S Gong, JG Lees, J Yin, LW Yap, AM Kong, Q Shi, R Fu, Q Zhu, ... Nature Communications 13 (1), 7259, 2022 | 25 | 2022 |
Scalable generation of nanovesicles from human-induced pluripotent stem cells for cardiac repair J Lozano, A Rai, JG Lees, H Fang, B Claridge, SY Lim, DW Greening International Journal of Molecular Sciences 23 (22), 14334, 2022 | 24 | 2022 |
Cellular interplay between cardiomyocytes and non-myocytes in diabetic cardiomyopathy RJ Phang, RH Ritchie, DJ Hausenloy, JG Lees, SY Lim Cardiovascular Research 119 (3), 668-690, 2023 | 23 | 2023 |
Bio-engineering a tissue flap utilizing a porous scaffold incorporating a human induced pluripotent stem cell-derived endothelial cell capillary network connected to a vascular … AM Kong, KK Yap, SY Lim, D Marre, A Pébay, Y Gerrand, JG Lees, ... Acta biomaterialia 94, 281-294, 2019 | 21 | 2019 |
Mitochondrial fusion by M1 promotes embryoid body cardiac differentiation of human pluripotent stem cells JG Lees, AM Kong, YC Chen, P Sivakumaran, D Hernández, A Pébay, ... Stem Cells International 2019 (1), 6380135, 2019 | 21 | 2019 |
Nicotinamide adenine dinucleotide induces a bivalent metabolism and maintains pluripotency in human embryonic stem cells JG Lees, DK Gardner, AJ Harvey Stem Cells 38 (5), 624-638, 2020 | 16 | 2020 |
Retinal ganglion cell-specific genetic regulation in primary open-angle glaucoma M Daniszewski, A Senabouth, HH Liang, X Han, GE Lidgerwood, ... Cell Genomics 2 (6), 2022 | 13 | 2022 |
Cellular pathophysiology of Friedreich's ataxia cardiomyopathy JG Lees, M Napierala, A Pébay, M Dottori, SY Lim International Journal of Cardiology 346, 71-78, 2022 | 12 | 2022 |
Mitochondrial dynamin-related protein Drp1: a new player in cardio-oncology Y Deng, DTM Ngo, JK Holien, JG Lees, SY Lim Current oncology reports 24 (12), 1751-1763, 2022 | 10 | 2022 |
Development of a CRISPRi human retinal pigmented epithelium model for functional study of age-related macular degeneration genes JH Wang, D Urrutia-Cabrera, JG Lees, S Mesa Mora, T Nguyen, ... International Journal of Molecular Sciences 24 (4), 3417, 2023 | 7 | 2023 |
Cardiomyocyte intercellular signalling increases oxidative stress and reprograms the global‐and phospho‐proteome of cardiac fibroblasts B Claridge, A Rai, JG Lees, H Fang, SY Lim, DW Greening Journal of Extracellular Biology 2 (12), e125, 2023 | 4 | 2023 |
Human vascularised cardiac organoids for disease modelling J Lees, A Kong, G Mitchell, S Lim Heart, Lung and Circulation 28, S216, 2019 | 3 | 2019 |