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Jarmon G Lees
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Pluripotent stem cell metabolism and mitochondria: beyond ATP
JG Lees, DK Gardner, AJ Harvey
Stem cells international 2017 (1), 2874283, 2017
852017
Fine-tuning the cardiac O-GlcNAcylation regulatory enzymes governs the functional and structural phenotype of the diabetic heart
D Prakoso, SY Lim, JR Erickson, RS Wallace, JG Lees, M Tate, H Kiriazis, ...
Cardiovascular research 118 (1), 212-225, 2022
592022
Sustained subcutaneous delivery of secretome of human cardiac stem cells promotes cardiac repair following myocardial infarction
AR Kompa, DW Greening, AM Kong, PJ McMillan, H Fang, R Saxena, ...
Cardiovascular Research 117 (3), 918-929, 2021
522021
Hydralazine protects the heart against acute ischaemia/reperfusion injury by inhibiting Drp1-mediated mitochondrial fission
SB Kalkhoran, J Kriston-Vizi, S Hernandez-Resendiz, GE Crespo-Avilan, ...
Cardiovascular Research 118 (1), 282-294, 2022
442022
Mitochondrial and glycolytic remodeling during nascent neural differentiation of human pluripotent stem cells
JG Lees, DK Gardner, AJ Harvey
Development 145 (20), dev168997, 2018
372018
Oxygen regulates human pluripotent stem cell metabolic flux
JG Lees, TS Cliff, A Gammilonghi, JG Ryall, S Dalton, DK Gardner, ...
Stem Cells International 2019 (1), 8195614, 2019
362019
Amorphous SiO2 nanoparticles promote cardiac dysfunction via the opening of the mitochondrial permeability transition pore in rat heart and human cardiomyocytes
O Lozano, C Silva-Platas, H Chapoy-Villanueva, BE Pérez, JG Lees, ...
Particle and Fibre Toxicology 17, 1-16, 2020
352020
Distinct profiles of human embryonic stem cell metabolism and mitochondria identified by oxygen
JG Lees, J Rathjen, JR Sheedy, DK Gardner, AJ Harvey
Reproduction 150 (4), 367-382, 2015
332015
A soft and ultrasensitive force sensing diaphragm for probing cardiac organoids instantaneously and wirelessly
Q Lyu, S Gong, JG Lees, J Yin, LW Yap, AM Kong, Q Shi, R Fu, Q Zhu, ...
Nature Communications 13 (1), 7259, 2022
252022
Scalable generation of nanovesicles from human-induced pluripotent stem cells for cardiac repair
J Lozano, A Rai, JG Lees, H Fang, B Claridge, SY Lim, DW Greening
International Journal of Molecular Sciences 23 (22), 14334, 2022
242022
Cellular interplay between cardiomyocytes and non-myocytes in diabetic cardiomyopathy
RJ Phang, RH Ritchie, DJ Hausenloy, JG Lees, SY Lim
Cardiovascular Research 119 (3), 668-690, 2023
232023
Bio-engineering a tissue flap utilizing a porous scaffold incorporating a human induced pluripotent stem cell-derived endothelial cell capillary network connected to a vascular …
AM Kong, KK Yap, SY Lim, D Marre, A Pébay, Y Gerrand, JG Lees, ...
Acta biomaterialia 94, 281-294, 2019
212019
Mitochondrial fusion by M1 promotes embryoid body cardiac differentiation of human pluripotent stem cells
JG Lees, AM Kong, YC Chen, P Sivakumaran, D Hernández, A Pébay, ...
Stem Cells International 2019 (1), 6380135, 2019
212019
Nicotinamide adenine dinucleotide induces a bivalent metabolism and maintains pluripotency in human embryonic stem cells
JG Lees, DK Gardner, AJ Harvey
Stem Cells 38 (5), 624-638, 2020
162020
Retinal ganglion cell-specific genetic regulation in primary open-angle glaucoma
M Daniszewski, A Senabouth, HH Liang, X Han, GE Lidgerwood, ...
Cell Genomics 2 (6), 2022
132022
Cellular pathophysiology of Friedreich's ataxia cardiomyopathy
JG Lees, M Napierala, A Pébay, M Dottori, SY Lim
International Journal of Cardiology 346, 71-78, 2022
122022
Mitochondrial dynamin-related protein Drp1: a new player in cardio-oncology
Y Deng, DTM Ngo, JK Holien, JG Lees, SY Lim
Current oncology reports 24 (12), 1751-1763, 2022
102022
Development of a CRISPRi human retinal pigmented epithelium model for functional study of age-related macular degeneration genes
JH Wang, D Urrutia-Cabrera, JG Lees, S Mesa Mora, T Nguyen, ...
International Journal of Molecular Sciences 24 (4), 3417, 2023
72023
Cardiomyocyte intercellular signalling increases oxidative stress and reprograms the global‐and phospho‐proteome of cardiac fibroblasts
B Claridge, A Rai, JG Lees, H Fang, SY Lim, DW Greening
Journal of Extracellular Biology 2 (12), e125, 2023
42023
Human vascularised cardiac organoids for disease modelling
J Lees, A Kong, G Mitchell, S Lim
Heart, Lung and Circulation 28, S216, 2019
32019
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