Ferrocifen type anti cancer drugs G Jaouen, A Vessières, S Top Chemical Society Reviews 44 (24), 8802-8817, 2015 | 553 | 2015 |
Synthesis, biochemical properties and molecular modelling studies of organometallic specific estrogen receptor modulators (SERMs), the ferrocifens and hydroxyferrocifens … S Top, A Vessières, G Leclercq, J Quivy, J Tang, J Vaissermann, M Huché, ... Chemistry–A European Journal 9 (21), 5223-5236, 2003 | 500 | 2003 |
The first organometallic selective estrogen receptor modulators (SERMs) and their relevance to breast cancer G Jaouen, S Top, A Vessieres, G Leclercq, MJ McGlinchey Current medicinal chemistry 11 (18), 2505-2517, 2004 | 305 | 2004 |
Studies on organometallic selective estrogen receptor modulators.(SERMs) Dual activity in the hydroxy-ferrocifen series S Top, A Vessieres, C Cabestaing, I Laios, G Leclercq, C Provot, ... Journal of Organometallic Chemistry 637, 500-506, 2001 | 303 | 2001 |
Modification of the estrogenic properties of diphenols by the incorporation of ferrocene. Generation of antiproliferative effects in vitro A Vessieres, S Top, P Pigeon, E Hillard, L Boubeker, D Spera, G Jaouen Journal of medicinal chemistry 48 (12), 3937-3940, 2005 | 245 | 2005 |
Ferrocenyl hydroxytamoxifen: a prototype for a new range of oestradiol receptor site-directed cytotoxics S Top, J Tang, A Vessières, D Carrez, C Provot, G Jaouen Chemical Communications, 955-956, 1996 | 225 | 1996 |
Rhenium Carbonyl Complexes of. beta.-Estradiol Derivatives with High Affinity for the Estradiol Receptor: An Approach to Selective Organometallic Radiopharmaceuticals S Top, H El Hafa, A Vessieres, J Quivy, J Vaissermann, DW Hughes, ... Journal of the American Chemical Society 117 (32), 8372-8380, 1995 | 223 | 1995 |
Facile route to ferrocifen, 1-[4-(2-dimethylaminoethoxy)]-1-(phenyl-2-ferrocenyl-but-1-ene), first organometallic analogue of tamoxifen, by the McMurry reaction S Top, B Dauer, J Vaissermann, G Jaouen Journal of organometallic chemistry 541 (1-2), 355-361, 1997 | 202 | 1997 |
Ferrocenyl quinone methides as strong antiproliferative agents: formation by metabolic and chemical oxidation of ferrocenyl phenols P Herson, GØ Jaouen, D Mansuy Angew. Chem 121, 9288-9290, 2009 | 199 | 2009 |
Ferrocifens and ferrocifenols as new potential weapons against breast cancer A Nguyen, A Vessières, EA Hillard, S Top, P Pigeon, G Jaouen Chimia 61 (11), 716-716, 2007 | 194 | 2007 |
New paradigms for synthetic pathways inspired by bioorganometallic chemistry G Jaouen, S Top, A Vessières, R Alberto Journal of Organometallic Chemistry 600 (1-2), 23-36, 2000 | 161 | 2000 |
Metal complex SERMs (selective oestrogen receptor modulators). The influence of different metal units on breast cancer cell antiproliferative effects A Vessières, S Top, W Beck, E Hillard, G Jaouen Dalton Transactions, 529-541, 2006 | 150 | 2006 |
Selective estrogen receptor modulators in the ruthenocene series. Synthesis and biological behavior P Pigeon, S Top, A Vessières, M Huché, EA Hillard, E Salomon, G Jaouen Journal of medicinal chemistry 48 (8), 2814-2821, 2005 | 139 | 2005 |
Organometallic estrogens: synthesis, interaction with lamb uterine estrogen receptor, and detection by infrared spectroscopy A Vessieres, S Top, AA Ismail, IS Butler, M Louer, G Jaouen Biochemistry 27 (18), 6659-6666, 1988 | 130 | 1988 |
N-Alkylation of nitriles using chromium tricarbonyl complexes of benzyl alcohol and its derivatives: New perspectives for the Ritter reaction S Top, G Jaouen The Journal of Organic Chemistry 46 (1), 78-82, 1981 | 129 | 1981 |
Labeling of proteins by organometallic complexes of rhenium (I). Synthesis and biological activity of the conjugates M Salmain, M Gunn, A Gorfti, S Top, G Jaouen Bioconjugate chemistry 4 (6), 425-433, 1993 | 125 | 1993 |
Metal carbonyl fragments as a new class of markers in molecular biology G Jaouen, A Vessieres, S Top, AA Ismail, IS Butler Journal of the American Chemical Society 107 (16), 4778-4780, 1985 | 123 | 1985 |
Synthesis and structure–activity relationships of the first ferrocenyl-aryl-hydantoin derivatives of the nonsteroidal antiandrogen nilutamide O Payen, S Top, A Vessières, E Brulé, MA Plamont, M J. McGlinchey, ... Journal of medicinal chemistry 51 (6), 1791-1799, 2008 | 117 | 2008 |
Evidence for targeting thioredoxin reductases with ferrocenyl quinone methides. A possible molecular basis for the antiproliferative effect of hydroxyferrocifens on cancer cells A Citta, A Folda, A Bindoli, P Pigeon, S Top, A Vessières, M Salmain, ... Journal of Medicinal Chemistry 57 (21), 8849-8859, 2014 | 108 | 2014 |
Chromium tricarbonyl complexes of estradiol derivatives: differentiation of. alpha.-and. beta.-diastereoisomers using 1-and 2-dimensional NMR spectroscopy at 500 MHz S Top, G Jaouen, A Vessieres, JP Abjean, D Davoust, CA Rodger, ... Organometallics 4 (12), 2143-2150, 1985 | 106 | 1985 |