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Molly O'Reilly
Molly O'Reilly
Dutch Heart Foundation (Hartstichting) Research Fellow, University of Amsterdam
在 bham.ac.uk 的电子邮件经过验证
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引用次数
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Generating inner ear organoids containing putative cochlear hair cells from human pluripotent stem cells
M Jeong, M O’reilly, NK Kirkwood, J Al-Aama, M Lako, CJ Kros, ...
Cell death & disease 9 (9), 922, 2018
812018
d-Tubocurarine and berbamine: alkaloids that are permeant blockers of the hair cell's mechano-electrical transducer channel and protect from aminoglycoside toxicity
NK Kirkwood, M O'reilly, M Derudas, EJ Kenyon, R Huckvale, ...
Frontiers in cellular neuroscience 11, 262, 2017
482017
Gentamicin affects the bioenergetics of isolated mitochondria and collapses the mitochondrial membrane potential in cochlear sensory hair cells
M O’Reilly, L Young, NK Kirkwood, GP Richardson, CJ Kros, AL Moore
Frontiers in cellular neuroscience 13, 416, 2019
302019
Exploring the neurogenic differentiation of human dental pulp stem cells
AA Al-Maswary, M O’Reilly, AP Holmes, AD Walmsley, PR Cooper, ...
PLoS One 17 (11), e0277134, 2022
292022
Identification of ion-channel modulators that protect against aminoglycoside-induced hair cell death
EJ Kenyon, NK Kirkwood, SR Kitcher, M O’reilly, M Derudas, DM Cantillon, ...
JCI insight 2 (24), 2017
282017
Design, synthesis, and biological evaluation of a new series of carvedilol derivatives that protect sensory hair cells from aminoglycoside-induced damage by blocking the …
M O’Reilly, NK Kirkwood, EJ Kenyon, R Huckvale, DM Cantillon, ...
Journal of medicinal chemistry 62 (11), 5312-5329, 2019
272019
Diminished PLK2 induces cardiac fibrosis and promotes atrial fibrillation
SR Künzel, M Hoffmann, S Weber, K Künzel, S Kämmerer, M Günscht, ...
Circulation research 129 (8), 804-820, 2021
262021
High resolution optical mapping of cardiac electrophysiology in pre-clinical models
C O’Shea, J Winter, SN Kabir, M O’Reilly, SP Wells, O Baines, ...
Scientific Data 9 (1), 135, 2022
202022
Atrial resting membrane potential confers sodium current sensitivity to propafenone, flecainide and dronedarone
AP Holmes, P Saxena, SN Kabir, C O’Shea, SM Kuhlmann, S Gupta, ...
Heart Rhythm 18 (7), 1212-1220, 2021
172021
Effects of genetic background, sex, and age on murine atrial electrophysiology
J Obergassel, M O’Reilly, LC Sommerfeld, SN Kabir, C O’Shea, F Syeda, ...
EP Europace 23 (6), 958-969, 2021
162021
Familial atrial fibrillation mutation M1875T-SCN5A increases early sodium current and dampens the effect of flecainide
M O’Reilly, LC Sommerfeld, C O’Shea, S Broadway-Stringer, S Andaleeb, ...
Europace 25 (3), 1152-1161, 2023
142023
Increased atrial effectiveness of flecainide conferred by altered biophysical properties of sodium channels
S O'Brien, AP Holmes, DM Johnson, SN Kabir, C O'Shea, M O'Reilly, ...
Journal of Molecular and Cellular Cardiology 166, 23-35, 2022
132022
Charge and lipophilicity are required for effective block of the hair-cell mechano-electrical transducer channel by FM1-43 and its derivatives
M Derudas, M O’Reilly, NK Kirkwood, EJ Kenyon, S Grimsey, SR Kitcher, ...
Frontiers in cell and developmental biology 11, 1247324, 2023
42023
PITX2 deficiency leads to atrial mitochondrial dysfunction
JS Reyat, LC Sommerfeld, M O’Reilly, V Roth Cardoso, E Thiemann, ...
Cardiovascular Research 120 (15), 1907-1923, 2024
32024
Chronic Mexiletine Administration Increases Sodium Current in Non-Diseased Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
G Nasilli, AO Verkerk, M O’Reilly, L Yiangou, RP Davis, S Casini, ...
Biomedicines 12 (6), 1212, 2024
32024
Reduced plakoglobin increases the risk of sodium current defects and atrial conduction abnormalities in response to androgenic anabolic steroid abuse
LC Sommerfeld, AP Holmes, TY Yu, C O'Shea, DM Kavanagh, JM Pike, ...
The Journal of Physiology, 2024
32024
Ventricular hyperinnervation in a mouse model of catecholaminergic polymorphic ventricular tachycardia
M O'reilly, T De Waal, S Casini, CA Remme
Cardiovascular Research 120 (Supplement_1), cvae088. 098, 2024
22024
Publisher Correction: High resolution optical mapping of cardiac electrophysiology in pre-clinical models
C O’Shea, J Winter, SN Kabir, M O’Reilly, SP Wells, O Baines, ...
Scientific Data 11, 2024
12024
BS12 Succinate disrupts human and mouse atrial action potentials and modifies sodium channel kinetics
S Benson, M O’Reilly, M Cumberland, A Coney, K Gehmlich, P Kirchhof, ...
Heart 110 (Suppl 3), 252-252, 2024
2024
Electrophysiological comparison of left versus right stellate ganglia neurons
AO Verkerk, CA Remme, M O'Reilly
bioRxiv, 2024.10. 29.620825, 2024
2024
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