Generating inner ear organoids containing putative cochlear hair cells from human pluripotent stem cells M Jeong, M O’reilly, NK Kirkwood, J Al-Aama, M Lako, CJ Kros, ... Cell death & disease 9 (9), 922, 2018 | 81 | 2018 |
d-Tubocurarine and berbamine: alkaloids that are permeant blockers of the hair cell's mechano-electrical transducer channel and protect from aminoglycoside toxicity NK Kirkwood, M O'reilly, M Derudas, EJ Kenyon, R Huckvale, ... Frontiers in cellular neuroscience 11, 262, 2017 | 48 | 2017 |
Gentamicin affects the bioenergetics of isolated mitochondria and collapses the mitochondrial membrane potential in cochlear sensory hair cells M O’Reilly, L Young, NK Kirkwood, GP Richardson, CJ Kros, AL Moore Frontiers in cellular neuroscience 13, 416, 2019 | 30 | 2019 |
Exploring the neurogenic differentiation of human dental pulp stem cells AA Al-Maswary, M O’Reilly, AP Holmes, AD Walmsley, PR Cooper, ... PLoS One 17 (11), e0277134, 2022 | 29 | 2022 |
Identification of ion-channel modulators that protect against aminoglycoside-induced hair cell death EJ Kenyon, NK Kirkwood, SR Kitcher, M O’reilly, M Derudas, DM Cantillon, ... JCI insight 2 (24), 2017 | 28 | 2017 |
Design, synthesis, and biological evaluation of a new series of carvedilol derivatives that protect sensory hair cells from aminoglycoside-induced damage by blocking the … M O’Reilly, NK Kirkwood, EJ Kenyon, R Huckvale, DM Cantillon, ... Journal of medicinal chemistry 62 (11), 5312-5329, 2019 | 27 | 2019 |
Diminished PLK2 induces cardiac fibrosis and promotes atrial fibrillation SR Künzel, M Hoffmann, S Weber, K Künzel, S Kämmerer, M Günscht, ... Circulation research 129 (8), 804-820, 2021 | 26 | 2021 |
High resolution optical mapping of cardiac electrophysiology in pre-clinical models C O’Shea, J Winter, SN Kabir, M O’Reilly, SP Wells, O Baines, ... Scientific Data 9 (1), 135, 2022 | 20 | 2022 |
Atrial resting membrane potential confers sodium current sensitivity to propafenone, flecainide and dronedarone AP Holmes, P Saxena, SN Kabir, C O’Shea, SM Kuhlmann, S Gupta, ... Heart Rhythm 18 (7), 1212-1220, 2021 | 17 | 2021 |
Effects of genetic background, sex, and age on murine atrial electrophysiology J Obergassel, M O’Reilly, LC Sommerfeld, SN Kabir, C O’Shea, F Syeda, ... EP Europace 23 (6), 958-969, 2021 | 16 | 2021 |
Familial atrial fibrillation mutation M1875T-SCN5A increases early sodium current and dampens the effect of flecainide M O’Reilly, LC Sommerfeld, C O’Shea, S Broadway-Stringer, S Andaleeb, ... Europace 25 (3), 1152-1161, 2023 | 14 | 2023 |
Increased atrial effectiveness of flecainide conferred by altered biophysical properties of sodium channels S O'Brien, AP Holmes, DM Johnson, SN Kabir, C O'Shea, M O'Reilly, ... Journal of Molecular and Cellular Cardiology 166, 23-35, 2022 | 13 | 2022 |
Charge and lipophilicity are required for effective block of the hair-cell mechano-electrical transducer channel by FM1-43 and its derivatives M Derudas, M O’Reilly, NK Kirkwood, EJ Kenyon, S Grimsey, SR Kitcher, ... Frontiers in cell and developmental biology 11, 1247324, 2023 | 4 | 2023 |
PITX2 deficiency leads to atrial mitochondrial dysfunction JS Reyat, LC Sommerfeld, M O’Reilly, V Roth Cardoso, E Thiemann, ... Cardiovascular Research 120 (15), 1907-1923, 2024 | 3 | 2024 |
Chronic Mexiletine Administration Increases Sodium Current in Non-Diseased Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes G Nasilli, AO Verkerk, M O’Reilly, L Yiangou, RP Davis, S Casini, ... Biomedicines 12 (6), 1212, 2024 | 3 | 2024 |
Reduced plakoglobin increases the risk of sodium current defects and atrial conduction abnormalities in response to androgenic anabolic steroid abuse LC Sommerfeld, AP Holmes, TY Yu, C O'Shea, DM Kavanagh, JM Pike, ... The Journal of Physiology, 2024 | 3 | 2024 |
Ventricular hyperinnervation in a mouse model of catecholaminergic polymorphic ventricular tachycardia M O'reilly, T De Waal, S Casini, CA Remme Cardiovascular Research 120 (Supplement_1), cvae088. 098, 2024 | 2 | 2024 |
Publisher Correction: High resolution optical mapping of cardiac electrophysiology in pre-clinical models C O’Shea, J Winter, SN Kabir, M O’Reilly, SP Wells, O Baines, ... Scientific Data 11, 2024 | 1 | 2024 |
BS12 Succinate disrupts human and mouse atrial action potentials and modifies sodium channel kinetics S Benson, M O’Reilly, M Cumberland, A Coney, K Gehmlich, P Kirchhof, ... Heart 110 (Suppl 3), 252-252, 2024 | | 2024 |
Electrophysiological comparison of left versus right stellate ganglia neurons AO Verkerk, CA Remme, M O'Reilly bioRxiv, 2024.10. 29.620825, 2024 | | 2024 |