Proteomic Analysis of Ubiquitin Ligase KEAP1 Reveals Associated Proteins That Inhibit NRF2 Ubiquitination BE Hast, D Goldfarb, KM Mulvaney, MA Hast, PF Siesser, F Yan, ... Cancer research 73 (7), 2199-2210, 2013 | 300 | 2013 |
NRF2 activation in cancer: from DNA to protein EW Cloer, D Goldfarb, TP Schrank, BE Weissman, MB Major Cancer research 79 (5), 889-898, 2019 | 150 | 2019 |
Cancer-Derived Mutations in KEAP1 Impair NRF2 Degradation but not Ubiquitination BE Hast, EW Cloer, D Goldfarb, H Li, PF Siesser, F Yan, V Walter, ... Cancer research 74 (3), 808-817, 2014 | 143 | 2014 |
Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1 JS Harrison, EM Cornett, D Goldfarb, PA DaRosa, ZM Li, F Yan, ... Elife 5, e17101, 2016 | 136 | 2016 |
Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell M Puray-Chavez, KM LaPak, TP Schrank, JL Elliott, DP Bhatt, ... Cell Reports 36 (2), 2021 | 133 | 2021 |
The Dark Kinase Knowledgebase: an online compendium of knowledge and experimental results of understudied kinases ME Berginski, N Moret, C Liu, D Goldfarb, PK Sorger, SM Gomez Nucleic acids research 49 (D1), D529-D535, 2021 | 92 | 2021 |
FOXP1 potentiates Wnt/β-catenin signaling in diffuse large B cell lymphoma MP Walker, CM Stopford, M Cederlund, F Fang, C Jahn, AD Rabinowitz, ... Science signaling 8 (362), ra12-ra12, 2015 | 81 | 2015 |
Identification and characterization of MCM3 as a Kelch-like ECH-associated protein 1 (KEAP1) substrate KM Mulvaney, JP Matson, PF Siesser, TY Tamir, D Goldfarb, TM Jacobs, ... Journal of Biological Chemistry 291 (45), 23719-23733, 2016 | 76 | 2016 |
Comprehensive nucleosome interactome screen establishes fundamental principles of nucleosome binding A Skrajna, D Goldfarb, KM Kedziora, EM Cousins, GD Grant, CJ Spangler, ... Nucleic acids research 48 (17), 9415-9432, 2020 | 71 | 2020 |
A neomorphic cancer cell-specific role of MAGE-A4 in trans-lesion synthesis Y Gao, E Mutter-Rottmayer, AM Greenwalt, D Goldfarb, F Yan, Y Yang, ... Nature communications 7 (1), 12105, 2016 | 69 | 2016 |
Substrate trapping proteomics reveals targets of the βTrCP2/FBXW11 ubiquitin ligase TY Kim, PF Siesser, KL Rossman, D Goldfarb, K Mackinnon, F Yan, XH Yi, ... Molecular and cellular biology, 2015 | 66 | 2015 |
Discovering the microbial enzymes driving drug toxicity with activity-based protein profiling PB Jariwala, SJ Pellock, D Goldfarb, EW Cloer, M Artola, JB Simpson, ... ACS chemical biology 15 (1), 217-225, 2019 | 59 | 2019 |
p62-dependent phase separation of patient-derived KEAP1 mutations and NRF2 EW Cloer, PF Siesser, EM Cousins, D Goldfarb, DD Mowrey, JS Harrison, ... Molecular and cellular biology, 2018 | 59 | 2018 |
Microbial enzymes induce colitis by reactivating triclosan in the mouse gastrointestinal tract J Zhang, ME Walker, KZ Sanidad, H Zhang, Y Liang, E Zhao, ... Nature communications 13 (1), 136, 2022 | 53 | 2022 |
SNF5/INI1 deficiency redefines chromatin remodeling complex composition during tumor development D Wei, D Goldfarb, S Song, C Cannon, F Yan, D Sakellariou-Thompson, ... Molecular Cancer Research 12 (11), 1574-1585, 2014 | 41 | 2014 |
Competitive kinase enrichment proteomics reveals that abemaciclib inhibits GSK3β and activates WNT signaling EM Cousins, D Goldfarb, F Yan, J Roques, D Darr, GL Johnson, MB Major Molecular Cancer Research 16 (2), 333-344, 2018 | 40 | 2018 |
The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis S Menon, D Goldfarb, CT Ho, EW Cloer, NP Boyer, C Hardie, AJ Bock, ... Molecular biology of the cell 32 (4), 314-330, 2021 | 31 | 2021 |
Gain-of-function genetic screen of the kinome reveals BRSK2 as an inhibitor of the NRF2 transcription factor TY Tamir, BM Bowman, MJ Agajanian, D Goldfarb, TP Schrank, T Stohrer, ... Journal of cell science 133 (14), jcs241356, 2020 | 23 | 2020 |
PepSAVI-MS Reveals a Proline-rich Antimicrobial Peptide in Amaranthus tricolor TB Moyer, LR Heil, CL Kirkpatrick, D Goldfarb, WA Lefever, NC Parsley, ... Journal of natural products 82 (10), 2744-2753, 2019 | 22 | 2019 |
FAM123A binds to microtubules and inhibits the guanine nucleotide exchange factor ARHGEF2 to decrease actomyosin contractility PF Siesser, M Motolese, MP Walker, D Goldfarb, K Gewain, F Yan, ... Science signaling 5 (240), ra64-ra64, 2012 | 19 | 2012 |