Development of a synthetic live bacterial therapeutic for the human metabolic disease phenylketonuria VM Isabella, BN Ha, MJ Castillo, DJ Lubkowicz, SE Rowe, YA Millet, ... Nature biotechnology 36 (9), 857-864, 2018 | 537 | 2018 |
Safety and pharmacodynamics of an engineered E. coli Nissle for the treatment of phenylketonuria: a first-in-human phase 1/2a study MK Puurunen, J Vockley, SL Searle, SJ Sacharow, JA Phillips III, ... Nature metabolism 3 (8), 1125-1132, 2021 | 127 | 2021 |
Improvement of a synthetic live bacterial therapeutic for phenylketonuria with biosensor-enabled enzyme engineering KJ Adolfsen, I Callihan, CE Monahan, PJ Greisen, J Spoonamore, ... Nature communications 12 (1), 6215, 2021 | 79 | 2021 |
Characterization of an engineered live bacterial therapeutic for the treatment of phenylketonuria in a human gut-on-a-chip MT Nelson, MR Charbonneau, HG Coia, MJ Castillo, C Holt, ... Nature communications 12 (1), 2805, 2021 | 60 | 2021 |
Quantitative Protein Analysis Using Enzymatic [18O]Water Labeling MJ Castillo, KJ Reynolds, A Gomes, C Fenselau, X Yao Current Protocols in Protein Science 76 (1), 23.4. 1-23.4. 9, 2014 | 22 | 2014 |
Development of a mechanistic model to predict synthetic biotic activity in healthy volunteers and patients with phenylketonuria MR Charbonneau, WS Denney, NG Horvath, P Cantarella, MJ Castillo, ... Communications Biology 4 (1), 898, 2021 | 13 | 2021 |
Quantitative proteomics in development of disease protein biomarkers X Yao, AJ McShane, MJ Castillo Proteomic and metabolomic approaches to biomarker discovery, 259-278, 2013 | 12 | 2013 |
Nonisotopic reagents for a cost-effective increase in sample throughput of targeted quantitative proteomics MJ Castillo, AJ McShane, M Cai, Y Shen, L Wang, X Yao Analytical chemistry 87 (18), 9209-9216, 2015 | 11 | 2015 |
Quantitative proteomics in development of disease protein biomarkers L Wang, AJ McShane, MJ Castillo, X Yao Proteomic and Metabolomic Approaches to Biomarker Discovery, 261-288, 2020 | 4 | 2020 |
Peptide Dimethylation: Fragmentation Control via Distancing the Dimethylamino Group AJ McShane, Y Shen, MJ Castillo, X Yao Journal of The American Society for Mass Spectrometry 25 (10), 1694-1704, 2014 | 2 | 2014 |
Mass Spectrometry-Based Approaches for Targeted Quantitative Proteomics in Biomarker Development MJ Castillo | | 2015 |
ournal of The American Society for JA Loo, R Lakshmanan, JA Loo, AJ McShane, Y Shen, MJ Castillo, X Yao, ... Focus 1715, 1718, 0 | | |