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Mary Joan Castillo
Mary Joan Castillo
Takeda
在 takeda.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Development of a synthetic live bacterial therapeutic for the human metabolic disease phenylketonuria
VM Isabella, BN Ha, MJ Castillo, DJ Lubkowicz, SE Rowe, YA Millet, ...
Nature biotechnology 36 (9), 857-864, 2018
5372018
Safety and pharmacodynamics of an engineered E. coli Nissle for the treatment of phenylketonuria: a first-in-human phase 1/2a study
MK Puurunen, J Vockley, SL Searle, SJ Sacharow, JA Phillips III, ...
Nature metabolism 3 (8), 1125-1132, 2021
1272021
Improvement of a synthetic live bacterial therapeutic for phenylketonuria with biosensor-enabled enzyme engineering
KJ Adolfsen, I Callihan, CE Monahan, PJ Greisen, J Spoonamore, ...
Nature communications 12 (1), 6215, 2021
792021
Characterization of an engineered live bacterial therapeutic for the treatment of phenylketonuria in a human gut-on-a-chip
MT Nelson, MR Charbonneau, HG Coia, MJ Castillo, C Holt, ...
Nature communications 12 (1), 2805, 2021
602021
Quantitative Protein Analysis Using Enzymatic [18O]Water Labeling
MJ Castillo, KJ Reynolds, A Gomes, C Fenselau, X Yao
Current Protocols in Protein Science 76 (1), 23.4. 1-23.4. 9, 2014
222014
Development of a mechanistic model to predict synthetic biotic activity in healthy volunteers and patients with phenylketonuria
MR Charbonneau, WS Denney, NG Horvath, P Cantarella, MJ Castillo, ...
Communications Biology 4 (1), 898, 2021
132021
Quantitative proteomics in development of disease protein biomarkers
X Yao, AJ McShane, MJ Castillo
Proteomic and metabolomic approaches to biomarker discovery, 259-278, 2013
122013
Nonisotopic reagents for a cost-effective increase in sample throughput of targeted quantitative proteomics
MJ Castillo, AJ McShane, M Cai, Y Shen, L Wang, X Yao
Analytical chemistry 87 (18), 9209-9216, 2015
112015
Quantitative proteomics in development of disease protein biomarkers
L Wang, AJ McShane, MJ Castillo, X Yao
Proteomic and Metabolomic Approaches to Biomarker Discovery, 261-288, 2020
42020
Peptide Dimethylation: Fragmentation Control via Distancing the Dimethylamino Group
AJ McShane, Y Shen, MJ Castillo, X Yao
Journal of The American Society for Mass Spectrometry 25 (10), 1694-1704, 2014
22014
Mass Spectrometry-Based Approaches for Targeted Quantitative Proteomics in Biomarker Development
MJ Castillo
2015
ournal of The American Society for
JA Loo, R Lakshmanan, JA Loo, AJ McShane, Y Shen, MJ Castillo, X Yao, ...
Focus 1715, 1718, 0
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