Capillary K+-sensing initiates retrograde hyperpolarization to increase local cerebral blood flow TA Longden, F Dabertrand, M Koide, AL Gonzales, NR Tykocki, ... Nature neuroscience 20 (5), 717-726, 2017 | 444 | 2017 |
Vascular Inward Rectifier K+ Channels as External K+ Sensors in the Control of Cerebral Blood Flow TA Longden, MT Nelson Microcirculation 22 (3), 183-196, 2015 | 143 | 2015 |
Ion channel networks in the control of cerebral blood flow TA Longden, DC Hill-Eubanks, MT Nelson Journal of Cerebral Blood Flow & Metabolism 36 (3), 492-512, 2016 | 134 | 2016 |
PIP2 depletion promotes TRPV4 channel activity in mouse brain capillary endothelial cells OF Harraz, TA Longden, D Hill-Eubanks, MT Nelson Elife 7, e38689, 2018 | 126 | 2018 |
Dysfunction of mouse cerebral arteries during early aging M Balbi, M Ghosh, TA Longden, MJ Vega, B Gesierich, F Hellal, ... Journal of Cerebral Blood Flow & Metabolism 35 (9), 1445-1453, 2015 | 82 | 2015 |
Stress-induced glucocorticoid signaling remodels neurovascular coupling through impairment of cerebrovascular inwardly rectifying K+ channel function TA Longden, F Dabertrand, DC Hill-Eubanks, SE Hammack, MT Nelson Proceedings of the National Academy of Sciences 111 (20), 7462-7467, 2014 | 82 | 2014 |
Endothelial GqPCR activity controls capillary electrical signaling and brain blood flow through PIP2 depletion OF Harraz, TA Longden, F Dabertrand, D Hill-Eubanks, MT Nelson Proceedings of the National Academy of Sciences 115 (15), E3569-E3577, 2018 | 78 | 2018 |
Traumatic brain injury disrupts cerebrovascular tone through endothelial inducible nitric oxide synthase expression and nitric oxide gain of function N Villalba, SK Sonkusare, TA Longden, TL Tran, AM Sackheim, ... Journal of the American Heart Association 3 (6), e001474, 2014 | 72 | 2014 |
PIP2 corrects cerebral blood flow deficits in small vessel disease by rescuing capillary Kir2.1 activity F Dabertrand, OF Harraz, M Koide, TA Longden, AC Rosehart, ... Proceedings of the National Academy of Sciences 118 (17), e2025998118, 2021 | 54 | 2021 |
The capillary Kir channel as sensor and amplifier of neuronal signals: Modeling insights on K+-mediated neurovascular communication A Moshkforoush, B Ashenagar, OF Harraz, F Dabertrand, TA Longden, ... Proceedings of the National Academy of Sciences 117 (28), 16626-16637, 2020 | 54 | 2020 |
Local IP3 receptor–mediated Ca2+ signals compound to direct blood flow in brain capillaries TA Longden, A Mughal, GW Hennig, OF Harraz, B Shui, FK Lee, JC Lee, ... Science Advances 7 (30), eabh0101, 2021 | 51 | 2021 |
The ion channel and GPCR toolkit of brain capillary pericytes A Hariharan, N Weir, C Robertson, L He, C Betsholtz, TA Longden Frontiers in Cellular Neuroscience 14, 601324, 2020 | 42 | 2020 |
Intermediate‐conductance calcium‐activated potassium channels participate in neurovascular coupling TA Longden, KM Dunn, HJ Draheim, MT Nelson, AH Weston, G Edwards British journal of pharmacology 164 (3), 922-933, 2011 | 37 | 2011 |
Differential restoration of functional hyperemia by antihypertensive drug classes in hypertension-related cerebral small vessel disease M Koide, OF Harraz, F Dabertrand, TA Longden, HR Ferris, GC Wellman, ... The Journal of clinical investigation 131 (18), 2021 | 33 | 2021 |
Vascular control of the CO2/H+-dependent drive to breathe CM Cleary, TS Moreira, AC Takakura, MT Nelson, TA Longden, ... Elife 9, e59499, 2020 | 29 | 2020 |
Brain capillary pericytes are metabolic sentinels that control blood flow through a KATP channel-dependent energy switch A Hariharan, CD Robertson, DCG Garcia, TA Longden Cell reports 41 (13), 2022 | 28 | 2022 |
Pericytes and the control of blood flow in brain and heart TA Longden, G Zhao, A Hariharan, WJ Lederer Annual review of physiology 85 (1), 137-164, 2023 | 25 | 2023 |
Uncoupling of neurovascular communication after transient global cerebral ischemia is caused by impaired parenchymal smooth muscle Kir channel function GK Povlsen, TA Longden, AD Bonev, DC Hill-Eubanks, MT Nelson Journal of Cerebral Blood Flow & Metabolism 36 (7), 1195-1201, 2016 | 25 | 2016 |
Inhibition of vascular smooth muscle inward-rectifier K+ channels restores myogenic tone in mouse urinary bladder arterioles NR Tykocki, AD Bonev, TA Longden, TJ Heppner, MT Nelson American Journal of Physiology-Renal Physiology 312 (5), F836-F847, 2017 | 19 | 2017 |
Impaired capillary-to-arteriolar electrical signaling after traumatic brain injury A Mughal, AM Sackheim, M Sancho, TA Longden, S Russell, W Lockette, ... Journal of Cerebral Blood Flow & Metabolism 41 (6), 1313-1327, 2021 | 18 | 2021 |