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Thomas Longden
Thomas Longden
在 som.umaryland.edu 的电子邮件经过验证 - 首页
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引用次数
引用次数
年份
Capillary K+-sensing initiates retrograde hyperpolarization to increase local cerebral blood flow
TA Longden, F Dabertrand, M Koide, AL Gonzales, NR Tykocki, ...
Nature neuroscience 20 (5), 717-726, 2017
4442017
Vascular Inward Rectifier K+ Channels as External K+ Sensors in the Control of Cerebral Blood Flow
TA Longden, MT Nelson
Microcirculation 22 (3), 183-196, 2015
1432015
Ion channel networks in the control of cerebral blood flow
TA Longden, DC Hill-Eubanks, MT Nelson
Journal of Cerebral Blood Flow & Metabolism 36 (3), 492-512, 2016
1342016
PIP2 depletion promotes TRPV4 channel activity in mouse brain capillary endothelial cells
OF Harraz, TA Longden, D Hill-Eubanks, MT Nelson
Elife 7, e38689, 2018
1262018
Dysfunction of mouse cerebral arteries during early aging
M Balbi, M Ghosh, TA Longden, MJ Vega, B Gesierich, F Hellal, ...
Journal of Cerebral Blood Flow & Metabolism 35 (9), 1445-1453, 2015
822015
Stress-induced glucocorticoid signaling remodels neurovascular coupling through impairment of cerebrovascular inwardly rectifying K+ channel function
TA Longden, F Dabertrand, DC Hill-Eubanks, SE Hammack, MT Nelson
Proceedings of the National Academy of Sciences 111 (20), 7462-7467, 2014
822014
Endothelial GqPCR activity controls capillary electrical signaling and brain blood flow through PIP2 depletion
OF Harraz, TA Longden, F Dabertrand, D Hill-Eubanks, MT Nelson
Proceedings of the National Academy of Sciences 115 (15), E3569-E3577, 2018
782018
Traumatic brain injury disrupts cerebrovascular tone through endothelial inducible nitric oxide synthase expression and nitric oxide gain of function
N Villalba, SK Sonkusare, TA Longden, TL Tran, AM Sackheim, ...
Journal of the American Heart Association 3 (6), e001474, 2014
722014
PIP2 corrects cerebral blood flow deficits in small vessel disease by rescuing capillary Kir2.1 activity
F Dabertrand, OF Harraz, M Koide, TA Longden, AC Rosehart, ...
Proceedings of the National Academy of Sciences 118 (17), e2025998118, 2021
542021
The capillary Kir channel as sensor and amplifier of neuronal signals: Modeling insights on K+-mediated neurovascular communication
A Moshkforoush, B Ashenagar, OF Harraz, F Dabertrand, TA Longden, ...
Proceedings of the National Academy of Sciences 117 (28), 16626-16637, 2020
542020
Local IP3 receptor–mediated Ca2+ signals compound to direct blood flow in brain capillaries
TA Longden, A Mughal, GW Hennig, OF Harraz, B Shui, FK Lee, JC Lee, ...
Science Advances 7 (30), eabh0101, 2021
512021
The ion channel and GPCR toolkit of brain capillary pericytes
A Hariharan, N Weir, C Robertson, L He, C Betsholtz, TA Longden
Frontiers in Cellular Neuroscience 14, 601324, 2020
422020
Intermediate‐conductance calcium‐activated potassium channels participate in neurovascular coupling
TA Longden, KM Dunn, HJ Draheim, MT Nelson, AH Weston, G Edwards
British journal of pharmacology 164 (3), 922-933, 2011
372011
Differential restoration of functional hyperemia by antihypertensive drug classes in hypertension-related cerebral small vessel disease
M Koide, OF Harraz, F Dabertrand, TA Longden, HR Ferris, GC Wellman, ...
The Journal of clinical investigation 131 (18), 2021
332021
Vascular control of the CO2/H+-dependent drive to breathe
CM Cleary, TS Moreira, AC Takakura, MT Nelson, TA Longden, ...
Elife 9, e59499, 2020
292020
Brain capillary pericytes are metabolic sentinels that control blood flow through a KATP channel-dependent energy switch
A Hariharan, CD Robertson, DCG Garcia, TA Longden
Cell reports 41 (13), 2022
282022
Pericytes and the control of blood flow in brain and heart
TA Longden, G Zhao, A Hariharan, WJ Lederer
Annual review of physiology 85 (1), 137-164, 2023
252023
Uncoupling of neurovascular communication after transient global cerebral ischemia is caused by impaired parenchymal smooth muscle Kir channel function
GK Povlsen, TA Longden, AD Bonev, DC Hill-Eubanks, MT Nelson
Journal of Cerebral Blood Flow & Metabolism 36 (7), 1195-1201, 2016
252016
Inhibition of vascular smooth muscle inward-rectifier K+ channels restores myogenic tone in mouse urinary bladder arterioles
NR Tykocki, AD Bonev, TA Longden, TJ Heppner, MT Nelson
American Journal of Physiology-Renal Physiology 312 (5), F836-F847, 2017
192017
Impaired capillary-to-arteriolar electrical signaling after traumatic brain injury
A Mughal, AM Sackheim, M Sancho, TA Longden, S Russell, W Lockette, ...
Journal of Cerebral Blood Flow & Metabolism 41 (6), 1313-1327, 2021
182021
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