| Targeted deletion of the kynurenine aminotransferase II gene reveals a critical role of endogenous kynurenic acid in the regulation of synaptic transmission via α7 nicotinic … M Alkondon, EFR Pereira, P Yu, EZ Arruda, LEF Almeida, P Guidetti, ... Journal of Neuroscience 24 (19), 4635-4648, 2004 | 153 | 2004 |
| Nicotine at concentrations found in cigarette smokers activates and desensitizes nicotinic acetylcholine receptors in CA1 interneurons of rat hippocampus M Alkondon, EFR Pereira, LEF Almeida, WR Randall, EX Albuquerque Neuropharmacology 39 (13), 2726-2739, 2000 | 151 | 2000 |
| Increased BDNF expression in fetal brain in the valproic acid model of autism LEF Almeida, CD Roby, BK Krueger Molecular and Cellular Neuroscience 59, 57-62, 2014 | 106 | 2014 |
| Circulating mitochondrial DNA is a proinflammatory DAMP in sickle cell disease L Tumburu, S Ghosh-Choudhary, FT Seifuddin, EA Barbu, S Yang, ... Blood, The Journal of the American Society of Hematology 137 (22), 3116-3126, 2021 | 75 | 2021 |
| Modulation of social deficits and repetitive behaviors in a mouse model of autism: the role of the nicotinic cholinergic system L Wang, LEF Almeida, NA Spornick, N Kenyon, S Kamimura, ... Psychopharmacology 232, 4303-4316, 2015 | 71 | 2015 |
| The opioid antagonist naltrexone inhibits activity and alters expression of α7 and α4β2 nicotinic receptors in hippocampal neurons: implications for smoking cessation programs LEF Almeida, EFR Pereira, M Alkondon, WP Fawcett, WR Randall, ... Neuropharmacology 39 (13), 2740-2755, 2000 | 54 | 2000 |
| Rapamycin increases fetal hemoglobin and ameliorates the nociception phenotype in sickle cell mice A Khaibullina, LEF Almeida, L Wang, S Kamimura, ECC Wong, M Nouraie, ... Blood Cells, Molecules, and Diseases 55 (4), 363-372, 2015 | 41 | 2015 |
| Cognitive and behavior deficits in sickle cell mice are associated with profound neuropathologic changes in hippocampus and cerebellum L Wang, LEF Almeida, CM de Souza Batista, A Khaibullina, N Xu, ... Neurobiology of disease 85, 60-72, 2016 | 38 | 2016 |
| Sickle cell disease in mice is associated with sensitization of sensory nerve fibers N Kenyon, L Wang, N Spornick, A Khaibullina, LEF Almeida, Y Cheng, ... Experimental biology and medicine 240 (1), 87-98, 2015 | 35 | 2015 |
| Altered nocifensive behavior in animal models of autism spectrum disorder: the role of the nicotinic cholinergic system L Wang, LEF Almeida, M Nettleton, A Khaibullina, S Albani, S Kamimura, ... Neuropharmacology 111, 323-334, 2016 | 23 | 2016 |
| Sickle cell disease subjects and mouse models have elevated nitrite and cGMP levels in blood compartments LEF Almeida, S Kamimura, CM de Souza Batista, N Spornick, ... Nitric Oxide 94, 79-91, 2020 | 19 | 2020 |
| Dexmedetomidine ameliorates nocifensive behavior in humanized sickle cell mice G Calhoun, L Wang, LEF Almeida, N Kenyon, N Afsar, M Nouraie, ... European journal of pharmacology 754, 125-133, 2015 | 19 | 2015 |
| RON kinase inhibition reduces renal endothelial injury in sickle cell disease mice A Khaibullina, EA Adjei, N Afangbedji, A Ivanov, N Kumari, LEF Almeida, ... Haematologica 103 (5), 787, 2018 | 17 | 2018 |
| Mitapivat increases ATP and decreases oxidative stress and erythrocyte mitochondria retention in a SCD mouse model ZMN Quezado, S Kamimura, M Smith, X Wang, MR Heaven, S Jana, ... Blood Cells, Molecules, and Diseases 95, 102660, 2022 | 15 | 2022 |
| NLRP3 inflammasome and bruton tyrosine kinase inhibition interferes with upregulated platelet aggregation and in vitro thrombus formation in sickle cell mice S Vogel, S Kamimura, T Arora, ML Smith, LEF Almeida, CA Combs, ... Biochemical and biophysical research communications 555, 196-201, 2021 | 15 | 2021 |
| The corticosteroid compounds prednisolone and vamorolone do not alter the nociception phenotype and exacerbate liver injury in sickle cell mice LEF Almeida, JM Damsker, S Albani, N Afsar, S Kamimura, D Pratt, ... Scientific reports 8 (1), 6081, 2018 | 13 | 2018 |
| Validation of a method to directly and specifically measure nitrite in biological matrices LEF Almeida, S Kamimura, N Kenyon, A Khaibullina, L Wang, ... Nitric Oxide 45, 54-64, 2015 | 13 | 2015 |
| Sensitivity of neuronal nicotinic acetylcholine receptors to the opiate antagonists naltrexone and naloxone: receptor blockade and up-regulation LEF Almeida, EFR Pereira, AL Camara, A Maelicke, EX Albuquerque Bioorganic & medicinal chemistry letters 14 (8), 1879-1887, 2004 | 13 | 2004 |
| Blood collection vials and clinically used intravenous fluids contain significant amounts of nitrite LEF Almeida, S Kamimura, MY Nettleton, CM de Souza Batista, E Walek, ... Free Radical Biology and Medicine 108, 533-541, 2017 | 9 | 2017 |
| Autocrine activation of neuronal NMDA receptors by aspartate mediates dopamine-and cAMP-induced CREB-dependent gene transcription LEF Almeida, PD Murray, HR Zielke, CD Roby, TJ Kingsbury, BK Krueger Journal of Neuroscience 29 (40), 12702-12710, 2009 | 9 | 2009 |
