High glucose reduces megalin-mediated albumin endocytosis in renal proximal tubule cells through protein kinase B O-GlcNAcylation D de Barros Peruchetti, RP Silva-Aguiar, GM Siqueira, WB Dias, ... Journal of Biological Chemistry 293 (29), 11388-11400, 2018 | 47 | 2018 |
O-GlcNAcylation reduces proximal tubule protein reabsorption and promotes proteinuria in spontaneously hypertensive rats RP Silva-Aguiar, NCF Bezerra, MC Lucena, GM Sirtoli, RT Sudo, ... Journal of Biological Chemistry 293 (33), 12749-12758, 2018 | 41 | 2018 |
Albumin expands albumin reabsorption capacity in proximal tubule epithelial cells through a positive feedback loop between AKT and megalin RP Silva-Aguiar, DB Peruchetti, LS Florentino, CM Takiya, MP Marzolo, ... International Journal of Molecular Sciences 23 (2), 848, 2022 | 21 | 2022 |
Role of the renin-angiotensin system in the development of severe COVID-19 in hypertensive patients RP Silva-Aguiar, DB Peruchetti, PRM Rocco, AH Schmaier, PMR e Silva, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 319 (4 …, 2020 | 18 | 2020 |
The renin–angiotensin–aldosterone system: Role in pathogenesis and potential therapeutic target in COVID‐19 CL Braga, RP Silva‐Aguiar, D Battaglini, DB Peruchetti, C Robba, ... Pharmacology Research & Perspectives 8 (4), e00623, 2020 | 18 | 2020 |
IL-4 receptor α chain protects the kidney against tubule-interstitial injury induced by albumin overload DB Peruchetti, JL Silva-Filho, RP Silva-Aguiar, DE Teixeira, CM Takiya, ... Frontiers in Physiology 11, 172, 2020 | 18 | 2020 |
Megalin-mediated albumin endocytosis in renal proximal tubules is involved in the antiproteinuric effect of angiotensin II type 1 receptor blocker in a subclinical acute kidney … DB Peruchetti, PFR Barahuna-Filho, RP Silva-Aguiar, TP Abreu, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1865 (9), 129950, 2021 | 17 | 2021 |
Eugenol disrupts Plasmodium falciparum intracellular development during the erythrocytic cycle and protects against cerebral malaria KAO Pontes, LS Silva, EC Santos, AS Pinheiro, DE Teixeira, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1865 (3), 129813, 2021 | 17 | 2021 |
The angiotensin II/AT1 receptor pathway mediates malaria-induced acute kidney injury LS Silva, DB Peruchetti, RP Silva-Aguiar, TP Abreu, BKA Dal-Cheri, ... PLoS One 13 (9), e0203836, 2018 | 17 | 2018 |
Mesenchymal stromal cells from emphysematous donors and their extracellular vesicles are unable to reverse cardiorespiratory dysfunction in experimental severe emphysema MA Antunes, CL Braga, TB Oliveira, JZ Kitoko, LL Castro, DG Xisto, ... Frontiers in Cell and Developmental Biology 9, 661385, 2021 | 16 | 2021 |
Niclosamide attenuates lung vascular remodeling in experimental pulmonary arterial hypertension CL Braga, NS Felix, DE Teixeira, JB Vieira, RP Silva-Aguiar, RM Bose, ... European journal of pharmacology 887, 173438, 2020 | 15 | 2020 |
Lithium ameliorates tubule-interstitial injury through activation of the mTORC2/protein kinase B pathway DE Teixeira, DB Peruchetti, LS Silva, RP Silva-Aguiar, MB Oquendo, ... PLoS One 14 (4), e0215871, 2019 | 15 | 2019 |
Kinins Released by Erythrocytic Stages of Plasmodium falciparum Enhance Adhesion of Infected Erythrocytes to Endothelial Cells and Increase Blood Brain Barrier … LS Silva, AS Pinheiro, DE Teixeira, RP Silva-Aguiar, DB Peruchetti, ... Frontiers in Medicine 6, 75, 2019 | 14 | 2019 |
Subclinical acute kidney injury in COVID-19: possible mechanisms and future perspectives RP Silva-Aguiar, DE Teixeira, RAS Peres, DB Peruchetti, CP Gomes, ... International Journal of Molecular Sciences 23 (22), 14193, 2022 | 12 | 2022 |
Inhibition of SGLT2 co-transporter by dapagliflozin ameliorates tubular proteinuria and tubule-interstitial injury at the early stage of diabetic kidney disease RS Farias, RP Silva-Aguiar, DE Teixeira, CP Gomes, AAS Pinheiro, ... European Journal of Pharmacology 942, 175521, 2023 | 10 | 2023 |
Surface megalin expression is a target to the inhibitory effect of bradykinin on the renal albumin endocytosis SAS Alves, LS Florentino, DE Teixeira, RP Silva-Aguiar, DB Peruchetti, ... Peptides 146, 170646, 2021 | 8 | 2021 |
Inhibition of O-glcnacylation reduces cell viability and autophagy and increases sensitivity to chemotherapeutic temozolomide in glioblastoma AV Leonel, F Alisson-Silva, RCM Santos, RP Silva-Aguiar, JC Gomes, ... Cancers 15 (19), 4740, 2023 | 7 | 2023 |
O-GlcNAcylation in renal (Patho) physiology RP Silva-Aguiar, DB Peruchetti, AAS Pinheiro, C Caruso-Neves, WB Dias International Journal of Molecular Sciences 23 (19), 11260, 2022 | 7 | 2022 |
SARS-CoV-2 spike protein inhibits megalin-mediated albumin endocytosis in proximal tubule epithelial cells RP Silva-Aguiar, DE Teixeira, DB Peruchetti, LS Florentino, RAS Peres, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1868 (12), 166496, 2022 | 6 | 2022 |
The monoterpene 1, 8-cineole prevents cerebral edema in a murine model of severe malaria EC Santos, LS Silva, AS Pinheiro, DE Teixeira, DB Peruchetti, ... Plos one 17 (5), e0268347, 2022 | 6 | 2022 |