Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth KM Nieman, HA Kenny, CV Penicka, A Ladanyi, R Buell-Gutbrod, ... Nature medicine 17 (11), 1498-1503, 2011 | 2276 | 2011 |
The initial steps of ovarian cancer cell metastasis are mediated by MMP-2 cleavage of vitronectin and fibronectin HA Kenny, S Kaur, LM Coussens, E Lengyel The Journal of clinical investigation 118 (4), 1367-1379, 2008 | 440 | 2008 |
Loss of E-cadherin promotes ovarian cancer metastasis via α5-integrin, which is a therapeutic target K Sawada, AK Mitra, AR Radjabi, V Bhaskar, EO Kistner, M Tretiakova, ... Cancer research 68 (7), 2329-2339, 2008 | 437 | 2008 |
Adipocyte-induced CD36 expression drives ovarian cancer progression and metastasis A Ladanyi, A Mukherjee, HA Kenny, A Johnson, AK Mitra, S Sundaresan, ... Oncogene 37 (17), 2285-2301, 2018 | 435 | 2018 |
Neutrophils facilitate ovarian cancer premetastatic niche formation in the omentum WJ Lee, SY Ko, MS Mohamed, HA Kenny, E Lengyel, H Naora Journal of Experimental Medicine 216 (1), 176-194, 2019 | 365 | 2019 |
c-Met overexpression is a prognostic factor in ovarian cancer and an effective target for inhibition of peritoneal dissemination and invasion K Sawada, AR Radjabi, N Shinomiya, E Kistner, H Kenny, AR Becker, ... Cancer research 67 (4), 1670-1679, 2007 | 327 | 2007 |
Mesothelial cells promote early ovarian cancer metastasis through fibronectin secretion HA Kenny, CY Chiang, EA White, EM Schryver, M Habis, IL Romero, ... The Journal of clinical investigation 124 (10), 4614-4628, 2014 | 323 | 2014 |
Use of a novel 3D culture model to elucidate the role of mesothelial cells, fibroblasts and extra‐cellular matrices on adhesion and invasion of ovarian cancer cells to the omentum HA Kenny, T Krausz, SD Yamada, E Lengyel International journal of cancer 121 (7), 1463-1472, 2007 | 297 | 2007 |
Fibroblasts mobilize tumor cell glycogen to promote proliferation and metastasis M Curtis, HA Kenny, B Ashcroft, A Mukherjee, A Johnson, Y Zhang, ... Cell metabolism 29 (1), 141-155. e9, 2019 | 253 | 2019 |
Epithelial ovarian cancer experimental models E Lengyel, JE Burdette, HA Kenny, D Matei, J Pilrose, P Haluska, ... Oncogene 33 (28), 3619-3633, 2014 | 234 | 2014 |
MMP-2 functions as an early response protein in ovarian cancer metastasis HA Kenny, E Lengyel Cell cycle 8 (5), 683-688, 2009 | 197 | 2009 |
Quantitative high throughput screening using a primary human three-dimensional organotypic culture predicts in vivo efficacy HA Kenny, M Lal-Nag, EA White, M Shen, CY Chiang, AK Mitra, Y Zhang, ... Nature communications 6 (1), 6220, 2015 | 187 | 2015 |
Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesis C Cui, K Chakraborty, XA Tang, G Zhou, KQ Schoenfelt, KM Becker, ... Cell 184 (12), 3163-3177. e21, 2021 | 186 | 2021 |
Ovarian follicle development requires Smad3 D Tomic, KP Miller, HA Kenny, TK Woodruff, P Hoyer, JA Flaws Molecular endocrinology 18 (9), 2224-2240, 2004 | 169 | 2004 |
Thrombin induces tumor invasion through the induction and association of matrix metalloproteinase-9 and β1-integrin on the cell surface AR Radjabi, K Sawada, S Jagadeeswaran, A Eichbichler, HA Kenny, ... Journal of Biological Chemistry 283 (5), 2822-2834, 2008 | 110 | 2008 |
Cancer-derived small extracellular vesicles promote angiogenesis by heparin-bound, bevacizumab-insensitive VEGF, independent of vesicle uptake SY Ko, WJ Lee, HA Kenny, LH Dang, LM Ellis, E Jonasch, E Lengyel, ... Communications Biology 2 (1), 386, 2019 | 107 | 2019 |
Molecular pathways: trafficking of metabolic resources in the tumor microenvironment IL Romero, A Mukherjee, HA Kenny, LM Litchfield, E Lengyel Clinical Cancer Research 21 (4), 680-686, 2015 | 96 | 2015 |
Targeting the urokinase plasminogen activator receptor inhibits ovarian cancer metastasis HA Kenny, P Leonhardt, A Ladanyi, SD Yamada, A Montag, HK Im, ... Clinical Cancer Research 17 (3), 459-471, 2011 | 93 | 2011 |
β3-integrin expression on tumor cells inhibits tumor progression, reduces metastasis, and is associated with a favorable prognosis in patients with ovarian cancer S Kaur, HA Kenny, S Jagadeeswaran, MR Zillhardt, AG Montag, E Kistner, ... The American journal of pathology 175 (5), 2184-2196, 2009 | 90 | 2009 |
The first line of intra-abdominal metastatic attack: breaching the mesothelial cell layer HA Kenny, KM Nieman, AK Mitra, E Lengyel Cancer discovery 1 (2), 100-102, 2011 | 89 | 2011 |