SOX17 is a critical specifier of human primordial germ cell fate N Irie, L Weinberger, WWC Tang, T Kobayashi, S Viukov, YS Manor, ... Cell 160 (1), 253-268, 2015 | 832 | 2015 |
A unique gene regulatory network resets the human germline epigenome for development WWC Tang, S Dietmann, N Irie, HG Leitch, VI Floros, CR Bradshaw, ... Cell 161 (6), 1453-1467, 2015 | 687 | 2015 |
Specification and epigenetic programming of the human germ line WWC Tang, T Kobayashi, N Irie, S Dietmann, MA Surani Nature Reviews Genetics 17 (10), 585-600, 2016 | 423 | 2016 |
Principles of early human development and germ cell program from conserved model systems T Kobayashi, H Zhang, WWC Tang, N Irie, S Withey, D Klisch, A Sybirna, ... Nature 546 (7658), 416-420, 2017 | 293 | 2017 |
Segregation of mitochondrial DNA heteroplasmy through a developmental genetic bottleneck in human embryos VI Floros, A Pyle, S Dietmann, W Wei, WCW Tang, N Irie, B Payne, ... Nature cell biology 20 (2), 144-151, 2018 | 193 | 2018 |
NANOG alone induces germ cells in primed epiblast in vitro by activation of enhancers K Murakami, U Günesdogan, JJ Zylicz, WWC Tang, R Sengupta, ... Nature 529 (7586), 403-407, 2016 | 182 | 2016 |
A paradoxical teratogenic mechanism for retinoic acid LMY Lee, CY Leung, WWC Tang, HL Choi, YC Leung, PJ McCaffery, ... Proceedings of the National Academy of Sciences 109 (34), 13668-13673, 2012 | 161 | 2012 |
Primordial germ-cell development and epigenetic reprogramming in mammals HG Leitch, WWC Tang, MA Surani Current topics in developmental biology 104, 149-187, 2013 | 147 | 2013 |
Pluripotency and X chromosome dynamics revealed in pig pre-gastrulating embryos by single cell analysis P Ramos-Ibeas, F Sang, Q Zhu, WWC Tang, S Withey, D Klisch, L Wood, ... Nature communications 10 (1), 500, 2019 | 109 | 2019 |
A critical role of PRDM14 in human primordial germ cell fate revealed by inducible degrons A Sybirna, WWC Tang, M Pierson Smela, S Dietmann, WH Gruhn, ... Nature communications 11 (1), 1282, 2020 | 84 | 2020 |
Germ cell specification and pluripotency in mammals: a perspective from early embryogenesis N Irie, WWC Tang, M Azim Surani Reproductive medicine and biology 13, 203-215, 2014 | 81 | 2014 |
Derivation of hypermethylated pluripotent embryonic stem cells with high potency S Bao, WWC Tang, B Wu, S Kim, J Li, L Li, T Kobayashi, C Lee, Y Chen, ... Cell research 28 (1), 22-34, 2018 | 49 | 2018 |
Tracing the emergence of primordial germ cells from bilaminar disc rabbit embryos and pluripotent stem cells T Kobayashi, A Castillo-Venzor, CA Penfold, M Morgan, N Mizuno, ... Cell reports 37 (2), 2021 | 46 | 2021 |
Esrrb complementation rescues development of Nanog-null germ cells M Zhang, HG Leitch, WWC Tang, N Festuccia, E Hall-Ponsele, J Nichols, ... Cell reports 22 (2), 332-339, 2018 | 46 | 2018 |
Specification and epigenomic resetting of the pig germline exhibit conservation with the human lineage Q Zhu, F Sang, S Withey, W Tang, S Dietmann, D Klisch, P Ramos-Ibeas, ... Cell Reports 34 (6), 2021 | 42 | 2021 |
Sequential enhancer state remodelling defines human germline competence and specification WWC Tang, A Castillo-Venzor, WH Gruhn, T Kobayashi, CA Penfold, ... Nature cell biology 24 (4), 448-460, 2022 | 35 | 2022 |
Organoid modeling of human fetal lung alveolar development reveals mechanisms of cell fate patterning and neonatal respiratory disease K Lim, APA Donovan, W Tang, D Sun, P He, JP Pett, SA Teichmann, ... Cell Stem Cell 30 (1), 20-37. e9, 2023 | 31 | 2023 |
SOX9 maintains human foetal lung tip progenitor state by enhancing WNT and RTK signalling D Sun, O Llora Batlle, J van den Ameele, JC Thomas, P He, K Lim, ... The EMBO Journal 41 (21), e111338, 2022 | 18 | 2022 |
Specification of human germ cell fate with enhanced progression capability supported by hindgut organoids JP Alves-Lopes, FCK Wong, WWC Tang, WH Gruhn, NB Ramakrishna, ... Cell Reports 42 (1), 2023 | 17 | 2023 |
Epigenetic resetting in the human germ line entails histone modification remodeling WH Gruhn, WWC Tang, S Dietmann, JP Alves-Lopes, CA Penfold, ... Science Advances 9 (3), eade1257, 2023 | 14 | 2023 |