关注
Walfred Tang
Walfred Tang
Gurdon Institute, University of Cambridge
在 cam.ac.uk 的电子邮件经过验证
标题
引用次数
引用次数
年份
SOX17 is a critical specifier of human primordial germ cell fate
N Irie, L Weinberger, WWC Tang, T Kobayashi, S Viukov, YS Manor, ...
Cell 160 (1), 253-268, 2015
8322015
A unique gene regulatory network resets the human germline epigenome for development
WWC Tang, S Dietmann, N Irie, HG Leitch, VI Floros, CR Bradshaw, ...
Cell 161 (6), 1453-1467, 2015
6872015
Specification and epigenetic programming of the human germ line
WWC Tang, T Kobayashi, N Irie, S Dietmann, MA Surani
Nature Reviews Genetics 17 (10), 585-600, 2016
4232016
Principles of early human development and germ cell program from conserved model systems
T Kobayashi, H Zhang, WWC Tang, N Irie, S Withey, D Klisch, A Sybirna, ...
Nature 546 (7658), 416-420, 2017
2932017
Segregation of mitochondrial DNA heteroplasmy through a developmental genetic bottleneck in human embryos
VI Floros, A Pyle, S Dietmann, W Wei, WCW Tang, N Irie, B Payne, ...
Nature cell biology 20 (2), 144-151, 2018
1932018
NANOG alone induces germ cells in primed epiblast in vitro by activation of enhancers
K Murakami, U Günesdogan, JJ Zylicz, WWC Tang, R Sengupta, ...
Nature 529 (7586), 403-407, 2016
1822016
A paradoxical teratogenic mechanism for retinoic acid
LMY Lee, CY Leung, WWC Tang, HL Choi, YC Leung, PJ McCaffery, ...
Proceedings of the National Academy of Sciences 109 (34), 13668-13673, 2012
1612012
Primordial germ-cell development and epigenetic reprogramming in mammals
HG Leitch, WWC Tang, MA Surani
Current topics in developmental biology 104, 149-187, 2013
1472013
Pluripotency and X chromosome dynamics revealed in pig pre-gastrulating embryos by single cell analysis
P Ramos-Ibeas, F Sang, Q Zhu, WWC Tang, S Withey, D Klisch, L Wood, ...
Nature communications 10 (1), 500, 2019
1092019
A critical role of PRDM14 in human primordial germ cell fate revealed by inducible degrons
A Sybirna, WWC Tang, M Pierson Smela, S Dietmann, WH Gruhn, ...
Nature communications 11 (1), 1282, 2020
842020
Germ cell specification and pluripotency in mammals: a perspective from early embryogenesis
N Irie, WWC Tang, M Azim Surani
Reproductive medicine and biology 13, 203-215, 2014
812014
Derivation of hypermethylated pluripotent embryonic stem cells with high potency
S Bao, WWC Tang, B Wu, S Kim, J Li, L Li, T Kobayashi, C Lee, Y Chen, ...
Cell research 28 (1), 22-34, 2018
492018
Tracing the emergence of primordial germ cells from bilaminar disc rabbit embryos and pluripotent stem cells
T Kobayashi, A Castillo-Venzor, CA Penfold, M Morgan, N Mizuno, ...
Cell reports 37 (2), 2021
462021
Esrrb complementation rescues development of Nanog-null germ cells
M Zhang, HG Leitch, WWC Tang, N Festuccia, E Hall-Ponsele, J Nichols, ...
Cell reports 22 (2), 332-339, 2018
462018
Specification and epigenomic resetting of the pig germline exhibit conservation with the human lineage
Q Zhu, F Sang, S Withey, W Tang, S Dietmann, D Klisch, P Ramos-Ibeas, ...
Cell Reports 34 (6), 2021
422021
Sequential enhancer state remodelling defines human germline competence and specification
WWC Tang, A Castillo-Venzor, WH Gruhn, T Kobayashi, CA Penfold, ...
Nature cell biology 24 (4), 448-460, 2022
352022
Organoid modeling of human fetal lung alveolar development reveals mechanisms of cell fate patterning and neonatal respiratory disease
K Lim, APA Donovan, W Tang, D Sun, P He, JP Pett, SA Teichmann, ...
Cell Stem Cell 30 (1), 20-37. e9, 2023
312023
SOX9 maintains human foetal lung tip progenitor state by enhancing WNT and RTK signalling
D Sun, O Llora Batlle, J van den Ameele, JC Thomas, P He, K Lim, ...
The EMBO Journal 41 (21), e111338, 2022
182022
Specification of human germ cell fate with enhanced progression capability supported by hindgut organoids
JP Alves-Lopes, FCK Wong, WWC Tang, WH Gruhn, NB Ramakrishna, ...
Cell Reports 42 (1), 2023
172023
Epigenetic resetting in the human germ line entails histone modification remodeling
WH Gruhn, WWC Tang, S Dietmann, JP Alves-Lopes, CA Penfold, ...
Science Advances 9 (3), eade1257, 2023
142023
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