Synthetic genetic polymers capable of heredity and evolution VB Pinheiro, AI Taylor, C Cozens, M Abramov, M Renders, S Zhang, ... Science 336 (6079), 341-344, 2012 | 771 | 2012 |
Catalysts from synthetic genetic polymers AI Taylor, VB Pinheiro, MJ Smola, AS Morgunov, S Peak-Chew, C Cozens, ... Nature 518 (7539), 427-430, 2015 | 291 | 2015 |
Selection of 2′-deoxy-2′-fluoroarabinonucleotide (FANA) aptamers that bind HIV-1 reverse transcriptase with picomolar affinity I Alves Ferreira-Bravo, C Cozens, P Holliger, JJ DeStefano Nucleic acids research 43 (20), 9587-9599, 2015 | 137 | 2015 |
The Scottish structural proteomics facility: targets, methods and outputs M Oke, LG Carter, KA Johnson, H Liu, SA McMahon, X Yan, M Kerou, ... Journal of structural and functional genomics 11, 167-180, 2010 | 135 | 2010 |
A short adaptive path from DNA to RNA polymerases C Cozens, VB Pinheiro, A Vaisman, R Woodgate, P Holliger Proceedings of the National Academy of Sciences 109 (21), 8067-8072, 2012 | 125 | 2012 |
Phosphonomethyl Oligonucleotides as Backbone-Modified Artificial Genetic Polymers C Liu, C Cozens, F Jaziri, J Rozenski, A Marechal, S Dumbre, V Pezo, ... Journal of the American Chemical Society 140 (21), 6690-6699, 2018 | 57 | 2018 |
Darwin Assembly: fast, efficient, multi-site bespoke mutagenesis C Cozens, VB Pinheiro Nucleic acids research 46 (8), e51-e51, 2018 | 37 | 2018 |
Enzymatic Synthesis of Nucleic Acids with Defined Regioisomeric 2′‐5′ Linkages C Cozens, H Mutschler, GM Nelson, G Houlihan, AI Taylor, P Holliger Angewandte Chemie International Edition 54 (51), 15570-15573, 2015 | 24 | 2015 |
Kinetic analysis of N-alkylaryl carboxamide hexitol nucleotides as substrates for evolved polymerases M Renders, S Dumbre, M Abramov, D Kestemont, L Margamuljana, ... Nucleic acids research 47 (5), 2160-2168, 2019 | 11 | 2019 |
XNA Synthesis and Reverse Transcription by Engineered Thermophilic Polymerases C Cozens, VB Pinheiro Current protocols in chemical biology 10 (3), e47, 2018 | 9 | 2018 |
Enzymes P Holliger, C Cozens, VB Pinheiro, AI Taylor US Patent 9,169,471, 2015 | 9 | 2015 |
Enzymes P Holliger, C Cozens, VB Pinheiro, AI Taylor US Patent 9,938,511, 2018 | 4 | 2018 |
Machine learning-driven protein engineering: a case study in computational drug discovery HF Rickerby, K Putintseva, C Cozens Engineering Biology 4 (1), 7-9, 2020 | 3 | 2020 |
Enzymatische Synthese von Nukleinsäuren mit definierten regioisomeren 2′‐5′‐Verknüpfungen C Cozens, H Mutschler, GM Nelson, G Houlihan, AI Taylor, P Holliger Angewandte Chemie 127 (51), 15791-15794, 2015 | 1 | 2015 |
Methods and systems for protein engineering and production HF Rickerby, JEJ Field, EV Putintseva, C Cozens US Patent App. 17/610,127, 2022 | | 2022 |
Enzymes P Holliger, C Cozens, VB Pinheiro, AI Taylor US Patent App. 15/920,345, 2018 | | 2018 |
Polymerase capable of producing non-dna nucleotide polymers. VB Bernardes Pinheiro, C Cozens, P Holliger | | 2013 |
Adaptive path from DNA to RNA and ANA polymerases C Cozens University of Cambridge, 2012 | | 2012 |
Enzymatic Synthesis of Nucleic Acids with Defined Regioisomeric 2о-5о Linkages C Cozens, H Mutschler, GM Nelson, G Houlihan, AI Taylor, P Holliger | | |