| Structural basis of membrane disruption and cellular toxicity by α-synuclein oligomers G Fusco, SW Chen, PTF Williamson, R Cascella, M Perni, JA Jarvis, ... Science 358 (6369), 1440-1443, 2017 | 604 | 2017 |
| Direct observation of the three regions in α-synuclein that determine its membrane-bound behaviour G Fusco, A De Simone, T Gopinath, V Vostrikov, M Vendruscolo, ... Nature communications 5 (1), 3827, 2014 | 452 | 2014 |
| C-terminal calcium binding of α-synuclein modulates synaptic vesicle interaction J Lautenschläger, AD Stephens, G Fusco, F Ströhl, N Curry, ... Nature communications 9 (1), 712, 2018 | 285 | 2018 |
| Structural basis of synaptic vesicle assembly promoted by α-synuclein G Fusco, T Pape, AD Stephens, P Mahou, AR Costa, CF Kaminski, ... Nature communications 7 (1), 12563, 2016 | 249 | 2016 |
| Extent of N-terminus exposure of monomeric alpha-synuclein determines its aggregation propensity AD Stephens, M Zacharopoulou, R Moons, G Fusco, N Seetaloo, A Chiki, ... Nature communications 11 (1), 2820, 2020 | 114 | 2020 |
| Structural ensembles of membrane-bound α-synuclein reveal the molecular determinants of synaptic vesicle affinity G Fusco, A De Simone, P Arosio, M Vendruscolo, G Veglia, CM Dobson Scientific reports 6 (1), 27125, 2016 | 97 | 2016 |
| The docking of synaptic vesicles on the presynaptic membrane induced by α-synuclein is modulated by lipid composition WK Man, B Tahirbegi, MD Vrettas, S Preet, L Ying, M Vendruscolo, ... Nature communications 12 (1), 927, 2021 | 82 | 2021 |
| Order and disorder in the physiological membrane binding of α-synuclein G Fusco, M Sanz-Hernandez, A De Simone Current opinion in structural biology 48, 49-57, 2018 | 65 | 2018 |
| Inhibition of α-synuclein fibril elongation by Hsp70 is governed by a kinetic binding competition between α-synuclein species FA Aprile, P Arosio, G Fusco, SW Chen, JR Kumita, A Dhulesia, P Tortora, ... Biochemistry 56 (9), 1177-1180, 2017 | 60 | 2017 |
| Conformational recognition of an intrinsically disordered protein JM Krieger, G Fusco, M Lewitzky, PC Simister, J Marchant, C Camilloni, ... Biophysical journal 106 (8), 1771-1779, 2014 | 60 | 2014 |
| The N-terminal acetylation of α-synuclein changes the affinity for lipid membranes but not the structural properties of the bound state M Runfola, A De Simone, M Vendruscolo, CM Dobson, G Fusco Scientific reports 10 (1), 204, 2020 | 59 | 2020 |
| The toxicity of misfolded protein oligomers is independent of their secondary structure M Vivoli Vega, R Cascella, SW Chen, G Fusco, A De Simone, CM Dobson, ... ACS Chemical Biology 14 (7), 1593-1600, 2019 | 43 | 2019 |
| Probing the origin of the toxicity of oligomeric aggregates of α-synuclein with antibodies R Cascella, M Perni, SW Chen, G Fusco, C Cecchi, M Vendruscolo, ... ACS chemical biology 14 (6), 1352-1362, 2019 | 42 | 2019 |
| Membrane interactions and toxicity by misfolded protein oligomers M Gonzalez-Garcia, G Fusco, A De Simone Frontiers in Cell and Developmental Biology 9, 642623, 2021 | 41 | 2021 |
| Structural basis for natural product selection and export by bacterial ABC transporters M Romano, G Fusco, HG Choudhury, S Mehmood, CV Robinson, S Zirah, ... ACS chemical biology 13 (6), 1598-1609, 2018 | 37 | 2018 |
| Molecular determinants of the interaction of EGCG with ordered and disordered proteins G Fusco, M Sanz‐Hernandez, FS Ruggeri, M Vendruscolo, CM Dobson, ... Biopolymers 109 (10), e23117, 2018 | 32 | 2018 |
| A role of cholesterol in modulating the binding of α-synuclein to synaptic-like vesicles WK Man, A De Simone, JD Barritt, M Vendruscolo, CM Dobson, G Fusco Frontiers in neuroscience 14, 18, 2020 | 27 | 2020 |
| Modeling Parkinson’s disease neuropathology and symptoms by intranigral inoculation of preformed human α-synuclein oligomers L Boi, A Pisanu, MF Palmas, G Fusco, E Carboni, MA Casu, V Satta, ... International journal of molecular sciences 21 (22), 8535, 2020 | 23 | 2020 |
| Comparative Studies in the A30P and A53T α-Synuclein C. elegans Strains to Investigate the Molecular Origins of Parkinson's Disease M Perni, A Van der Goot, R Limbocker, TJ Van Ham, FA Aprile, CK Xu, ... Frontiers in Cell and Developmental Biology 9, 552549, 2021 | 16 | 2021 |
| 1H, 13C and 15N resonance assignments of human muscle acylphosphatase G Fusco, A De Simone, STD Hsu, F Bemporad, M Vendruscolo, F Chiti, ... Biomolecular NMR assignments 6, 27-29, 2012 | 16 | 2012 |
Alfonso De SimoneProfessor at University of Naples Federico II在 unina.it 的电子邮件经过验证
