Germline variation in BRCA1/2 is highly ethnic‐specific: Evidence from over 30,000 Chinese hereditary breast and ovarian cancer patients SP Bhaskaran, K Chandratre, H Gupta, L Zhang, X Wang, J Cui, YC Kim, ... International journal of cancer 145 (4), 962-973, 2019 | 73 | 2019 |
Classification of VUS and unclassified variants in BRCA1 BRCT repeats by molecular dynamics simulation S Sinha, SM Wang Computational and Structural Biotechnology Journal 18, 723-736, 2020 | 72 | 2020 |
Mechanistic principles behind molecular mechanism of Rifampicin resistance in mutant RNA polymerase beta subunit of Mycobacterium tuberculosis. A Singh, S Grover, S Sinha, M Das, P Somvanshi, A Grover Journal of Cellular Biochemistry, 2017 | 45 | 2017 |
Structural insights into the binding of MMP9 inhibitors A Tandon, S Sinha Bioinformation 5 (8), 310, 2011 | 44 | 2011 |
Combining Ramachandran plot and molecular dynamics simulation for structural-based variant classification: Using TP53 variants as model B Tam, S Sinha, SM Wang Computational and Structural Biotechnology Journal 18, 4033-4039, 2020 | 41 | 2020 |
Applications of molecular dynamics simulation in protein study S Sinha, B Tam, SM Wang Membranes 12 (9), 844, 2022 | 32 | 2022 |
Fragment based G-QSAR and molecular dynamics based mechanistic simulations into hydroxamic-based HDAC inhibitors against spinocerebellar ataxia S Sinha, C Tyagi, S Goyal, P Somvanshi, A Grover Journal of Biomolecular Structure and Dynamics, 1-39, 2015 | 28 | 2015 |
Simulation based investigation of deleterious nsSNPs in ATXN2 gene and its structural consequence toward spinocerebellar ataxia S Sinha, S Verma, A Singh, P Somvanshi, A Grover Journal of Cellular Biochemistry 119 (1), 499-510, 2018 | 19 | 2018 |
Mechanistic insights into the binding of class IIa HDAC inhibitors toward spinocerebellar ataxia type-2: a 3D-QSAR and pharmacophore modeling approach S Sinha, S Goyal, P Somvanshi, A Grover Frontiers in Neuroscience 10, 606, 2017 | 17 | 2017 |
RBD double mutations of SARS-CoV-2 strains increase transmissibility through enhanced interaction between RBD and ACE2 receptor S Sinha, B Tam, SM Wang Viruses 14 (1), 1, 2021 | 16 | 2021 |
Helicobacter pylori neutrophil-activating protein: A potential Treg modulator suppressing allergic asthma? A Sehrawat, S Sinha, A Saxena Frontiers in Microbiology 6 (493), 2015 | 15 | 2015 |
Altered interaction between RBD and ACE2 receptor contributes towards the increased transmissibility of SARS CoV-2 delta, kappa, beta, and gamma strains with RBD double mutations. S Sinha, B Tam, SM Wang bioRxiv, https://doi.org/10.1101/2021.08.30.45830, 2021 | 14 | 2021 |
BRCA1 and BRCA2 Variation in Taiwanese General Population and Cancer cohort J Chian, S Sinha, SM Wang Frontiers in Molecular Biosciences 8, 552, 2021 | 9 | 2021 |
On the resolution of the sensitivity conjecture R Karthikeyan, S Sinha, V Patil Bulletin of the American Mathematical Society 57 (4), 615-638, 2020 | 9 | 2020 |
Insight into the inhibitor discrimination by FLT3 F691L. Verma S, Singh A, Kumari A, Pandey B, Jamal S, Goyal S, Sinha S, Grover A Chem Biol Drug Des., 2018 | 8* | 2018 |
Coupled genome-wide DNA methylation and transcription analysis identified rich biomarkers and drug targets in triple-negative breast cancer M Guo, S Sinha, SM Wang Cancers 11 (11), 1724, 2019 | 7 | 2019 |
Analyzing human behaviour using data analytics in booking a type hotel K Yesugade, V Bangre, S Sinha, S Kak, A Saxena 4th International conference on computing for sustainable global development …, 2017 | 7 | 2017 |
Ethnic‐specificity, evolution origin and deleteriousness of Asian BRCA variation revealed by over 7500 BRCA variants derived from Asian population Z Qin, J Li, B Tam, S Sinha, B Zhao, SP Bhaskaran, T Huang, X Wu, ... International journal of cancer 152 (6), 1159-1173, 2023 | 6 | 2023 |
Comprehensive Identification of Deleterious TP53 Missense VUS Variants Based on Their Impact on TP53 Structural Stability B Tam, S Sinha, Z Qin, SM Wang International Journal of Molecular Sciences 22 (21), 11345, 2021 | 5 | 2021 |
Highly diversified core promoters in the human genome and their effects on gene expression and disease predisposition H Gupta, K Chandratre, S Sinha, T Huang, X Wu, J Cui, MQ Zhang, ... BMC genomics 21, 1-12, 2020 | 5 | 2020 |