Targeted genomic rearrangements using CRISPR/Cas technology PS Choi, M Meyerson Nature communications 5 (1), 3728, 2014 | 394 | 2014 |
Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers X Zhang, PS Choi, JM Francis, M Imielinski, H Watanabe, AD Cherniack, ... Nature genetics 48 (2), 176-182, 2016 | 355 | 2016 |
A Pan-Cancer Analysis of Transcriptome Changes Associated with Somatic Mutations in U2AF1 Reveals Commonly Altered Splicing Events AN Brooks, PS Choi, L De Waal, T Sharifnia, M Imielinski, G Saksena, ... PloS one 9 (1), e87361, 2014 | 208 | 2014 |
MYC through miR-17-92 suppresses specific target genes to maintain survival, autonomous proliferation, and a neoplastic state Y Li, PS Choi, SC Casey, DL Dill, DW Felsher Cancer cell 26 (2), 262-272, 2014 | 203 | 2014 |
Identification of ADAR1 adenosine deaminase dependency in a subset of cancer cells HS Gannon, T Zou, MK Kiessling, GF Gao, D Cai, PS Choi, AP Ivan, ... Nature communications 9 (1), 5450, 2018 | 183 | 2018 |
The interaction between Myc and Miz1 is required to antagonize TGFβ-dependent autocrine signaling during lymphoma formation and maintenance J Van Riggelen, J Müller, T Otto, V Beuger, A Yetil, PS Choi, C Kosan, ... Genes & development 24 (12), 1281-1294, 2010 | 138 | 2010 |
P2Y-like receptor, GPR105 (P2Y14), identifies and mediates chemotaxis of bone-marrowhematopoietic stem cells BC Lee, T Cheng, GB Adams, EC Attar, N Miura, SB Lee, Y Saito, I Olszak, ... Genes & development 17 (13), 1592-1604, 2003 | 135 | 2003 |
Somatic superenhancer duplications and hotspot mutations lead to oncogenic activation of the KLF5 transcription factor X Zhang, PS Choi, JM Francis, GF Gao, JD Campbell, A Ramachandran, ... Cancer discovery 8 (1), 108-125, 2018 | 117 | 2018 |
An alternative splicing switch in FLNB promotes the mesenchymal cell state in human breast cancer J Li, PS Choi, CL Chaffer, K Labella, JH Hwang, AO Giacomelli, JW Kim, ... Elife 7, e37184, 2018 | 105 | 2018 |
Identification of cancer-cytotoxic modulators of PDE3A by predictive chemogenomics L De Waal, TA Lewis, MG Rees, A Tsherniak, X Wu, PS Choi, L Gechijian, ... Nature chemical biology 12 (2), 102-108, 2016 | 99 | 2016 |
Copy-number and gene dependency analysis reveals partial copy loss of wild-type SF3B1 as a novel cancer vulnerability BR Paolella, WJ Gibson, LM Urbanski, JA Alberta, TI Zack, ... Elife 6, e23268, 2017 | 81 | 2017 |
MET exon 14 mutation encodes an actionable therapeutic target in lung adenocarcinoma X Lu, N Peled, J Greer, W Wu, P Choi, AH Berger, S Wong, KY Jen, Y Seo, ... Cancer research 77 (16), 4498-4505, 2017 | 68 | 2017 |
Genome-scale analysis identifies paralog lethality as a vulnerability of chromosome 1p loss in cancer SR Viswanathan, MF Nogueira, CG Buss, JM Krill-Burger, MJ Wawer, ... Nature genetics 50 (7), 937-943, 2018 | 58 | 2018 |
Lymphomas that recur after MYC suppression continue to exhibit oncogene addiction PS Choi, J Van Riggelen, AJ Gentles, P Bachireddy, K Rakhra, SJ Adam, ... Proceedings of the National Academy of Sciences 108 (42), 17432-17437, 2011 | 52 | 2011 |
Survival and death signals can predict tumor response to therapy after oncogene inactivation PT Tran, PK Bendapudi, HJ Lin, P Choi, S Koh, J Chen, G Horng, ... Science translational medicine 3 (103), 103ra99-103ra99, 2011 | 50 | 2011 |
Multi-omics analysis identifies MGA as a negative regulator of the MYC pathway in lung adenocarcinoma P Llabata, Y Mitsuishi, PS Choi, D Cai, JM Francis, M Torres-Diz, ... Molecular Cancer Research 18 (4), 574-584, 2020 | 43 | 2020 |
Identification and Characterization of Oncogenic SOS1 Mutations in Lung Adenocarcinoma D Cai, PS Choi, M Gelbard, M Meyerson Molecular Cancer Research 17 (4), 1002-1012, 2019 | 41 | 2019 |
Chromatin looping shapes KLF5-dependent transcriptional programs in human epithelial cancers Y Liu, B Guo, E Aguilera-Jimenez, VS Chu, J Zhou, Z Wu, JM Francis, ... Cancer research 80 (24), 5464-5477, 2020 | 34 | 2020 |
Activation of Cre recombinase alone can induce complete tumor regression Y Li, PS Choi, SC Casey, DW Felsher PLoS One 9 (9), e107589, 2014 | 31 | 2014 |
RNA-binding proteins of COSMIC importance in cancer PS Choi, A Thomas-Tikhonenko The Journal of clinical investigation 131 (18), 2021 | 24 | 2021 |