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Frank Dieterle
Frank Dieterle
Mulier Health, Dieterle Life Sciences Consulting, FHNW
在 frank-dieterle.de 的电子邮件经过验证 - 首页
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Probabilistic quotient normalization as robust method to account for dilution of complex biological mixtures. Application in 1H NMR metabonomics
F Dieterle, A Ross, G Schlotterbeck, H Senn
Analytical chemistry 78 (13), 4281-4290, 2006
18582006
Kidney injury molecule-1 outperforms traditional biomarkers of kidney injury in preclinical biomarker qualification studies
VS Vaidya, JS Ozer, F Dieterle, FB Collings, V Ramirez, S Troth, ...
Nature biotechnology 28 (5), 478-485, 2010
7722010
Next-generation biomarkers for detecting kidney toxicity
JV Bonventre, VS Vaidya, R Schmouder, P Feig, F Dieterle
Nature biotechnology 28 (5), 436-440, 2010
6272010
Renal biomarker qualification submission: a dialog between the FDA-EMEA and Predictive Safety Testing Consortium
F Dieterle, F Sistare, F Goodsaid, M Papaluca, JS Ozer, CP Webb, W Baer, ...
Nature biotechnology 28 (5), 455-462, 2010
4732010
Urinary clusterin, cystatin C, β2-microglobulin and total protein as markers to detect drug-induced kidney injury
F Dieterle, E Perentes, A Cordier, DR Roth, P Verdes, O Grenet, ...
Nature biotechnology 28 (5), 463-469, 2010
3972010
A panel of urinary biomarkers to monitor reversibility of renal injury and a serum marker with improved potential to assess renal function
JS Ozer, F Dieterle, S Troth, E Perentes, A Cordier, P Verdes, F Staedtler, ...
Nature biotechnology 28 (5), 486-494, 2010
2562010
Towards consensus practices to qualify safety biomarkers for use in early drug development
FD Sistare, F Dieterle, S Troth, DJ Holder, D Gerhold, ...
Nature biotechnology 28 (5), 446-454, 2010
1362010
Performance of novel kidney biomarkers in preclinical toxicity studies
D Hoffmann, M Adler, VS Vaidya, E Rached, L Mulrane, WM Gallagher, ...
Toxicological Sciences 116 (1), 8-22, 2010
1242010
Metabolic profiling technologies for biomarker discovery in biomedicine and drug development
G Schlotterbeck, A Ross, F Dieterle, H Senn
Pharmacogenomics 7 (7), 1055-1075, 2006
1022006
Impact of biomarker development on drug safety assessment
E Marrer, F Dieterle
Toxicology and applied pharmacology 243 (2), 167-179, 2010
932010
NMR and MS methods for metabonomics
F Dieterle, B Riefke, G Schlotterbeck, A Ross, H Senn, A Amberg
Drug Safety Evaluation: Methods and Protocols, 385-415, 2011
912011
NMR and MS Methods for Metabolomics
A Amberg, B Riefke, G Schlotterbeck, A Ross, H Senn, F Dieterle, M Keck
Drug safety evaluation: methods and protocols, 229-258, 2017
882017
NMR spectroscopy techniques for application to metabonomics
A Ross, G Schlotterbeck, F Dieterle, H Senn
The handbook of metabonomics and metabolomics 4, 55, 2007
822007
Urinary nucleosides as potential tumor markers evaluated by learning vector quantization
F Dieterle, S Müller-Hagedorn, HM Liebich, G Gauglitz
Artificial intelligence in medicine 28 (3), 265-279, 2003
782003
Tissue-specific, non-invasive toxicity biomarkers: translation from preclinical safety assessment to clinical safety monitoring
PY Muller, F Dieterle
Expert Opinion on Drug Metabolism & Toxicology 5 (9), 1023-1038, 2009
732009
Monitoring kidney safety in drug development: emerging technologies and their implications.
F Dieterle, E Marrer, E Suzuki, O Grenet, A Cordier, J Vonderscher
Current opinion in drug discovery & development 11 (1), 60-71, 2008
732008
Promises of biomarkers in drug development–a reality check
E Marrer, F Dieterle
Chemical Biology & Drug Design 69 (6), 381-394, 2007
702007
Metabolite projection analysis for fast identification of metabolites in metabonomics. Application in an amiodarone study
F Dieterle, A Ross, G Schlotterbeck, H Senn
Analytical Chemistry 78 (11), 3551-3561, 2006
622006
Growing neural networks for a multivariate calibration and variable selection of time-resolved measurements
F Dieterle, S Busche, G Gauglitz
Analytica Chimica Acta 490 (1-2), 71-83, 2003
532003
Multianalyte quantifications by means of integration of artificial neural networks, genetic algorithms and chemometrics for time-resolved analytical data
FJ Dieterle
Universität Tübingen, 2003
472003
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