Probabilistic quotient normalization as robust method to account for dilution of complex biological mixtures. Application in 1H NMR metabonomics F Dieterle, A Ross, G Schlotterbeck, H Senn Analytical chemistry 78 (13), 4281-4290, 2006 | 1858 | 2006 |
Kidney injury molecule-1 outperforms traditional biomarkers of kidney injury in preclinical biomarker qualification studies VS Vaidya, JS Ozer, F Dieterle, FB Collings, V Ramirez, S Troth, ... Nature biotechnology 28 (5), 478-485, 2010 | 772 | 2010 |
Next-generation biomarkers for detecting kidney toxicity JV Bonventre, VS Vaidya, R Schmouder, P Feig, F Dieterle Nature biotechnology 28 (5), 436-440, 2010 | 627 | 2010 |
Renal biomarker qualification submission: a dialog between the FDA-EMEA and Predictive Safety Testing Consortium F Dieterle, F Sistare, F Goodsaid, M Papaluca, JS Ozer, CP Webb, W Baer, ... Nature biotechnology 28 (5), 455-462, 2010 | 473 | 2010 |
Urinary clusterin, cystatin C, β2-microglobulin and total protein as markers to detect drug-induced kidney injury F Dieterle, E Perentes, A Cordier, DR Roth, P Verdes, O Grenet, ... Nature biotechnology 28 (5), 463-469, 2010 | 397 | 2010 |
A panel of urinary biomarkers to monitor reversibility of renal injury and a serum marker with improved potential to assess renal function JS Ozer, F Dieterle, S Troth, E Perentes, A Cordier, P Verdes, F Staedtler, ... Nature biotechnology 28 (5), 486-494, 2010 | 256 | 2010 |
Towards consensus practices to qualify safety biomarkers for use in early drug development FD Sistare, F Dieterle, S Troth, DJ Holder, D Gerhold, ... Nature biotechnology 28 (5), 446-454, 2010 | 136 | 2010 |
Performance of novel kidney biomarkers in preclinical toxicity studies D Hoffmann, M Adler, VS Vaidya, E Rached, L Mulrane, WM Gallagher, ... Toxicological Sciences 116 (1), 8-22, 2010 | 124 | 2010 |
Metabolic profiling technologies for biomarker discovery in biomedicine and drug development G Schlotterbeck, A Ross, F Dieterle, H Senn Pharmacogenomics 7 (7), 1055-1075, 2006 | 102 | 2006 |
Impact of biomarker development on drug safety assessment E Marrer, F Dieterle Toxicology and applied pharmacology 243 (2), 167-179, 2010 | 93 | 2010 |
NMR and MS methods for metabonomics F Dieterle, B Riefke, G Schlotterbeck, A Ross, H Senn, A Amberg Drug Safety Evaluation: Methods and Protocols, 385-415, 2011 | 91 | 2011 |
NMR and MS Methods for Metabolomics A Amberg, B Riefke, G Schlotterbeck, A Ross, H Senn, F Dieterle, M Keck Drug safety evaluation: methods and protocols, 229-258, 2017 | 88 | 2017 |
NMR spectroscopy techniques for application to metabonomics A Ross, G Schlotterbeck, F Dieterle, H Senn The handbook of metabonomics and metabolomics 4, 55, 2007 | 82 | 2007 |
Urinary nucleosides as potential tumor markers evaluated by learning vector quantization F Dieterle, S Müller-Hagedorn, HM Liebich, G Gauglitz Artificial intelligence in medicine 28 (3), 265-279, 2003 | 78 | 2003 |
Tissue-specific, non-invasive toxicity biomarkers: translation from preclinical safety assessment to clinical safety monitoring PY Muller, F Dieterle Expert Opinion on Drug Metabolism & Toxicology 5 (9), 1023-1038, 2009 | 73 | 2009 |
Monitoring kidney safety in drug development: emerging technologies and their implications. F Dieterle, E Marrer, E Suzuki, O Grenet, A Cordier, J Vonderscher Current opinion in drug discovery & development 11 (1), 60-71, 2008 | 73 | 2008 |
Promises of biomarkers in drug development–a reality check E Marrer, F Dieterle Chemical Biology & Drug Design 69 (6), 381-394, 2007 | 70 | 2007 |
Metabolite projection analysis for fast identification of metabolites in metabonomics. Application in an amiodarone study F Dieterle, A Ross, G Schlotterbeck, H Senn Analytical Chemistry 78 (11), 3551-3561, 2006 | 62 | 2006 |
Growing neural networks for a multivariate calibration and variable selection of time-resolved measurements F Dieterle, S Busche, G Gauglitz Analytica Chimica Acta 490 (1-2), 71-83, 2003 | 53 | 2003 |
Multianalyte quantifications by means of integration of artificial neural networks, genetic algorithms and chemometrics for time-resolved analytical data FJ Dieterle Universität Tübingen, 2003 | 47 | 2003 |