| A small-molecule inhibitor of Tgf-β signaling replaces Sox2 in reprogramming by inducing Nanog JK Ichida, J Blanchard, K Lam, EY Son, JE Chung, D Egli, KM Loh, ... Cell stem cell 5 (5), 491-503, 2009 | 965 | 2009 |
| Reconstruction of the human blood–brain barrier in vitro reveals a pathogenic mechanism of APOE4 in pericytes JW Blanchard, M Bula, J Davila-Velderrain, LA Akay, L Zhu, A Frank, ... Nature medicine 26 (6), 952-963, 2020 | 213 | 2020 |
| APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes JW Blanchard, LA Akay, J Davila-Velderrain, D von Maydell, H Mathys, ... Nature 611 (7937), 769-779, 2022 | 202 | 2022 |
| Selective conversion of fibroblasts into peripheral sensory neurons JW Blanchard, KT Eade, A Szűcs, V Lo Sardo, RK Tsunemoto, D Williams, ... Nature neuroscience 18 (1), 25-35, 2015 | 187* | 2015 |
| Diverse reprogramming codes for neuronal identity R Tsunemoto, S Lee, A Szűcs, P Chubukov, I Sokolova, JW Blanchard, ... Nature 557 (7705), 375-380, 2018 | 110 | 2018 |
| Glucocorticoid compounds modify smoothened localization and hedgehog pathway activity Y Wang, L Davidow, AC Arvanites, J Blanchard, K Lam, K Xu, V Oza, ... Chemistry & biology 19 (8), 972-982, 2012 | 74 | 2012 |
| Gamma frequency sensory stimulation in mild probable Alzheimer’s dementia patients: Results of feasibility and pilot studies D Chan, HJ Suk, BL Jackson, NP Milman, D Stark, EB Klerman, ... PloS one 17 (12), e0278412, 2022 | 66 | 2022 |
| Selective identification of hedgehog pathway antagonists by direct analysis of smoothened ciliary translocation Y Wang, AC Arvanites, L Davidow, J Blanchard, K Lam, JW Yoo, S Coy, ... ACS chemical biology 7 (6), 1040-1048, 2012 | 49 | 2012 |
| Forward engineering neuronal diversity using direct reprogramming RK Tsunemoto, KT Eade, JW Blanchard, KK Baldwin The EMBO journal 34 (11), 1445-1455, 2015 | 48 | 2015 |
| Efficient induction of pluripotent stem cells using small molecule compounds J Ichida, J Blanchard, L Rubin, K Eggan, K Lam US Patent App. 13/119,848, 2012 | 48 | 2012 |
| Replacing reprogramming factors with antibodies selected from combinatorial antibody libraries JW Blanchard, J Xie, N El-Mecharrafie, S Gross, S Lee, RA Lerner, ... Nature biotechnology 35 (10), 960-968, 2017 | 44 | 2017 |
| Dissecting the complexities of Alzheimer disease with in vitro models of the human brain JW Blanchard, MB Victor, LH Tsai Nature Reviews Neurology 18 (1), 25-39, 2022 | 40 | 2022 |
| Gamma frequency sensory stimulation in probable mild Alzheimer’s dementia patients: results of a preliminary clinical trial D Chan, HJ Suk, BL Jackson, NP Milman, D Stark, EB Klerman, ... | 36* | 2021 |
| Proteomic profiling dataset of chemical perturbations in multiple biological backgrounds DO Dele-Oni, KE Christianson, SB Egri, AS Vaca Jacome, KC DeRuff, ... Scientific Data 8 (1), 226, 2021 | 11 | 2021 |
| Unraveling the paradox of statins with human neurons: new leads in Alzheimer’s disease JW Blanchard, LH Tsai Cell stem cell 24 (3), 347-349, 2019 | 11 | 2019 |
| Molecular profiling of human substantia nigra identifies diverse neuron types associated with vulnerability in Parkinson’s disease Q Wang, M Wang, I Choi, L Sarrafha, M Liang, L Ho, K Farrell, ... Science advances 10 (2), eadi8287, 2024 | 6 | 2024 |
| Disruption of lysosomal proteolysis in astrocytes facilitates midbrain organoid proteostasis failure in an early-onset Parkinson’s disease model G Morrone Parfitt, E Coccia, C Goldman, K Whitney, R Reyes, L Sarrafha, ... Nature Communications 15 (1), 447, 2024 | 5 | 2024 |
| Modeling the blood-brain barrier using human-induced pluripotent stem cells LA Mesentier-Louro, N Suhy, D Broekaart, M Bula, AC Pereira, ... Stem Cell-Based Neural Model Systems for Brain Disorders, 135-151, 2023 | 4 | 2023 |
| Author Correction: Reconstruction of the human blood–brain barrier in vitro reveals a pathogenic mechanism of APOE4 in pericytes JW Blanchard, M Bula, J Davila-Velderrain, LA Akay, L Zhu, A Frank, ... Nature Medicine 27 (2), 356-356, 2021 | 4 | 2021 |
| Engineered 3D Immuno-Glial-Neurovascular Human miBrain Model AE Stanton, A Bubnys, E Agbas, B James, DS Park, A Jiang, RL Pinals, ... bioRxiv, 2023.08. 15.553453, 2023 | 3 | 2023 |
