Effects of acute and repeated treatment with the biased mu opioid receptor agonist TRV130 (oliceridine) on measures of antinociception, gastrointestinal function, and abuse … AA Altarifi, B David, KH Muchhala, BE Blough, H Akbarali, SS Negus Journal of Psychopharmacology 31 (6), 730-739, 2017 | 158 | 2017 |
Chemotherapy induced gastrointestinal toxicities HI Akbarali, KH Muchhala, DK Jessup, S Cheatham Advances in cancer research 155, 131-166, 2022 | 26 | 2022 |
Glycine and GABAA ultra-sensitive ethanol receptors as novel tools for alcohol and brain research A Naito, KH Muchhala, L Asatryan, JR Trudell, GE Homanics, DI Perkins, ... Molecular Pharmacology 86 (6), 635-646, 2014 | 15 | 2014 |
Role of β-arrestin-2 in short-and long-term opioid tolerance in the dorsal root ganglia KH Muchhala, JC Jacob, WL Dewey, HI Akbarali European journal of pharmacology 899, 174007, 2021 | 13 | 2021 |
Manipulations of extracellular Loop 2 in α1 GlyR ultra-sensitive ethanol receptors (USERs) enhance receptor sensitivity to isoflurane, ethanol, and lidocaine, but not propofol A Naito, KH Muchhala, J Trang, L Asatryan, JR Trudell, GE Homanics, ... Neuroscience 297, 68-77, 2015 | 8 | 2015 |
Sex-specific role for serotonin 5-HT2A receptor in modulation of opioid-induced antinociception and reward in mice S Sierra, KH Muchhala, DK Jessup, KM Contreras, UH Shah, DL Stevens, ... Neuropharmacology 209, 108988, 2022 | 7 | 2022 |
The guts of the opioid crisis KH Muchhala, JC Jacob, M Kang, WL Dewey, HI Akbarali Physiology 36 (5), 315-323, 2021 | 5 | 2021 |
Morphine exacerbates experimental colitis-induced depression of nesting in mice SM Cheatham, KH Muchhala, E Koseli, JC Jacob, E Komla, SS Negus, ... Frontiers in Pain Research 2, 738499, 2021 | 4 | 2021 |
The “culture” of pain control: A review of opioid-induced dysbiosis (OID) in antinociceptive tolerance RA Mischel, KH Muchhala, WL Dewey, HI Akbarali The Journal of Pain 21 (7-8), 751-762, 2020 | 4 | 2020 |
The role of morphine-induced impairment of intestinal epithelial antibacterial activity in dysbiosis and its impact on the microbiota-gut-brain axis K Muchhala, M Kang, E Koseli, J Poklis, Q Xu, W Dewey, J Fettweis, ... Research Square, 2023 | 3 | 2023 |
Chronic Morphine Induces IL-18 in Ileum Myenteric Plexus Neurons Through Mu-opioid Receptor Activation in Cholinergic and VIPergic Neurons KH Muchhala, E Koseli, AR Gade, K Woods, S Minai, M Kang, ... Journal of Neuroimmune Pharmacology 17 (1-2), 111-130, 2022 | 3 | 2022 |
Rapid tolerance to morphine in the myenteric neurons of the small intestine is independent of β-arrestin-2 and mediated by PKC KH Muchhala, JC Jacob, I Alam, S Hasan, A Khan, M Kang, WL Dewey, ... BioRxiv, 2020.07. 17.209437, 2020 | 3 | 2020 |
Mutations In GABAA Receptor Loop 2 Create Ultrasensitive Ethanol Receptors (USERs) Sensitive To Micromolar Ethanol Concentrations A Naito, K Muchhala, L Asatryan, JR Trudell, GE Homanics, DL Davies, ... ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH 37, 242A-242A, 2013 | 1 | 2013 |
Endocannabinoid biosynthetic enzymes regulate pain response via LKB1–AMPK signaling M Chen, M Shin, TB Ware, G Donvito, KH Muchhala, R Mischel, ... Proceedings of the National Academy of Sciences 120 (52), e2304900120, 2023 | | 2023 |
Enhanced Cholinergic Action of Myenteric Neurons During Chemotherapy Induced Diarrhea S Cheatham, KH Muchhala, HI Akbarali Journal of Pharmacology and Experimental Therapeutics 385 (S3), 2023 | | 2023 |
Chronic Morphine and Fentanyl Induce Intestinal Dysbiosis by Decreasing the Antimicrobial Activity of the Ileum KH Muchhala, GK Mahon, E Koseli, J Bethea, M Kang, HI Akbarali Journal of Pharmacology and Experimental Therapeutics 385 (S3), 368, 2023 | | 2023 |
O-13: INHIBITION OF THE ENDOCANNABINOID REGULATING ENZYME MONOACYLGLYCEROL LIPASE AMELIORATES THE HYPER-NOCICEPTIVE PHENOTYPE IN THE BERKELEY MOUSE MODEL OF SICKLE CELL DISEASE K GOLDSBOROUGH, K MUCHHALA, A ADU-GYAMFI, S HERZ, ... HemaSphere 6 (Suppl), 2022 | | 2022 |
Distinct Mechanisms of Morphine Tolerance in Enteric Neurons and Dorsal Root Ganglia Neurons: Role of β‐arrestin‐2 KH Muchhala, HI Akbarali The FASEB Journal 36, 2022 | | 2022 |
An investigation on the role of β-arrestin 2, protein kinase C and sex on the mechanism of morphine tolerance in the mouse ileum KH Muchhala | | 2019 |
μ-Opioid Receptors Co-Expressed in Cholinergic Neurons of Mouse Ileum Myenteric Plexus Develop Tolerance to Chronic Morphine Exposure K Muchhala, A Gade, WL Dewey, HI Akbarali Gastroenterology 152 (5), S710, 2017 | | 2017 |