| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13436* | 2021 |
| Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formation KL Lim, KCM Chew, JMM Tan, C Wang, KKK Chung, Y Zhang, Y Tanaka, ... Journal of Neuroscience 25 (8), 2002-2009, 2005 | 635 | 2005 |
| Inducible expression of mutant α-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis Y Tanaka, S Engelender, S Igarashi, RK Rao, T Wanner, RE Tanzi, ... Human molecular genetics 10 (9), 919-926, 2001 | 629 | 2001 |
| Synphilin-1 associates with α-synuclein and promotes the formation of cytosolic inclusions S Engelender, Z Kaminsky, X Guo, AH Sharp, RK Amaravi, JJ Kleiderlein, ... Nature genetics 22 (1), 110-114, 1999 | 629 | 1999 |
| Huntingtin-associated Protein 1 (HAP1) Interacts with the p150Glued Bubunit of Dynactin S Engelender, AH Sharp, V Colomer, MK Tokito, A Lanahan, P Worley, ... Human molecular genetics 6 (13), 2205-2212, 1997 | 436 | 1997 |
| Synphilin‐1 is present in Lewy bodies in Parkinson's disease K Wakabayashi, S Engelender, M Yoshimoto, S Tsuji, CA Ross, ... Annals of Neurology: Official Journal of the American Neurological …, 2000 | 335 | 2000 |
| Monoubiquitylation of α-synuclein by seven in absentia homolog (SIAH) promotes its aggregation in dopaminergic cells R Rott, R Szargel, J Haskin, V Shani, A Shainskaya, I Manov, E Liani, ... Journal of Biological Chemistry 283 (6), 3316-3328, 2008 | 249 | 2008 |
| Ubiquitylation of synphilin-1 and α-synuclein by SIAH and its presence in cellular inclusions and Lewy bodies imply a role in Parkinson's disease E Liani, A Eyal, E Avraham, R Shemer, R Szargel, D Berg, A Bornemann, ... Proceedings of the National Academy of Sciences 101 (15), 5500-5505, 2004 | 236 | 2004 |
| The threshold theory for Parkinson's disease S Engelender, O Isacson Trends in neurosciences 40 (1), 4-14, 2017 | 224 | 2017 |
| Glycation potentiates α-synuclein-associated neurodegeneration in synucleinopathies H Vicente Miranda, ÉM Szegő, LMA Oliveira, C Breda, E Darendelioglu, ... Brain 140 (5), 1399-1419, 2017 | 214 | 2017 |
| α-Synuclein fate is determined by USP9X-regulated monoubiquitination R Rott, R Szargel, J Haskin, R Bandopadhyay, AJ Lees, V Shani, ... Proceedings of the National Academy of Sciences 108 (46), 18666-18671, 2011 | 213 | 2011 |
| Identification and functional characterization of a novel R621C mutation in the synphilin-1 gene in Parkinson's disease FP Marx, C Holzmann, KM Strauss, L Li, O Eberhardt, E Gerhardt, ... Human molecular genetics 12 (11), 1223-1231, 2003 | 195 | 2003 |
| SUMOylation and ubiquitination reciprocally regulate α-synuclein degradation and pathological aggregation R Rott, R Szargel, V Shani, H Hamza, M Savyon, F Abd Elghani, ... Proceedings of the National Academy of Sciences 114 (50), 13176-13181, 2017 | 179 | 2017 |
| Inhibition of creatine kinase by S-nitrosoglutathione H Wolosker, R Panizzutti, S Engelender FEBS letters 392 (3), 274-276, 1996 | 176 | 1996 |
| Human serine racemase: moleular cloning, genomic organization and functional analysis J De Miranda, A Santoro, S Engelender, H Wolosker Gene 256 (1-2), 183-188, 2000 | 171 | 2000 |
| Huntingtin-associated protein 1 (HAP1) binds to a Trio-like polypeptide, with a rac1 guanine nucleotide exchange factor domain V Colomer, S Engelender, AH Sharp, K Duan, JK Cooper, A Lanahan, ... Human molecular genetics 6 (9), 1519-1525, 1997 | 161 | 1997 |
| Phosphorylation of Parkin by the cyclin-dependent kinase 5 at the linker region modulates its ubiquitin-ligase activity and aggregation E Avraham, R Rott, E Liani, R Szargel, S Engelender Journal of Biological Chemistry 282 (17), 12842-12850, 2007 | 157 | 2007 |
| Ubiquitination of α-synuclein and autophagy in Parkinson's disease S Engelender Autophagy 4 (3), 372-374, 2008 | 153 | 2008 |
| Synphilin-1 is developmentally localized to synaptic terminals, and its association with synaptic vesicles is modulated by α-synuclein CS Ribeiro, K Carneiro, CA Ross, JRL Menezes, S Engelender Journal of Biological Chemistry 277 (26), 23927-23933, 2002 | 144 | 2002 |
| The PINK1, synphilin-1 and SIAH-1 complex constitutes a novel mitophagy pathway R Szargel, V Shani, F Abd Elghani, LN Mekies, E Liani, R Rott, ... Human molecular genetics 25 (16), 3476-3490, 2016 | 139 | 2016 |
