The kallikrein-related peptidase family: Dysregulation and functions during cancer progression T Kryza, ML Silva, D Loessner, N Heuzé-Vourc'h, JA Clements Biochimie 122, 283-299, 2016 | 103 | 2016 |
Post-GWAS in prostate cancer: from genetic association to biological contribution S Farashi, T Kryza, J Clements, J Batra Nature Reviews Cancer 19 (1), 46-59, 2019 | 97 | 2019 |
Remodelling of the tumour microenvironment by the kallikrein-related peptidases S Srinivasan, T Kryza, J Batra, J Clements Nature Reviews Cancer 22 (4), 223-238, 2022 | 46 | 2022 |
Downregulation of the neonatal Fc receptor expression in non-small cell lung cancer tissue is associated with a poor prognosis E Dalloneau, N Baroukh, K Mavridis, A Maillet, F Gueugnon, Y Courty, ... Oncotarget 7 (34), 54415, 2016 | 45 | 2016 |
Tenascin-W is a better cancer biomarker than tenascin-C for most human solid tumors F Brellier, E Martina, M Degen, N Heuzé-Vourc’h, A Petit, T Kryza, ... BMC clinical pathology 12, 1-10, 2012 | 43 | 2012 |
The CDCP1 signaling hub: a target for cancer detection and therapeutic intervention T Khan, T Kryza, NJ Lyons, Y He, JD Hooper Cancer research 81 (9), 2259-2269, 2021 | 40 | 2021 |
Revisiting glycogen in cancer: a conspicuous and targetable enabler of malignant transformation T Khan, MA Sullivan, JH Gunter, T Kryza, N Lyons, Y He, JD Hooper Frontiers in Oncology 10, 592455, 2020 | 37 | 2020 |
Angiogenesis stimulated by human kallikrein‐related peptidase 12 acting via a platelet‐derived growth factor B‐dependent paracrine pathway T Kryza, C Achard, C Parent, S Marchand‐Adam, A Guillon‐Munos, ... The FASEB Journal 28 (2), 740-751, 2014 | 36 | 2014 |
Engineering osteoblastic metastases to delineate the adaptive response of androgen-deprived prostate cancer in the bone metastatic microenvironment N Bock, A Shokoohmand, T Kryza, J Röhl, J Meijer, PA Tran, CC Nelson, ... Bone Research 7 (1), 13, 2019 | 28 | 2019 |
In vitro engineering of a bone metastases model allows for study of the effects of antiandrogen therapies in advanced prostate cancer N Bock, T Kryza, A Shokoohmand, J Röhl, A Ravichandran, ML Wille, ... Science advances 7 (27), eabg2564, 2021 | 27 | 2021 |
Effective targeting of intact and proteolysed CDCP1 for imaging and treatment of pancreatic ductal adenocarcinoma T Kryza, T Khan, S Puttick, C Li, KA Sokolowski, WC Brian, T Cuda, ... Theranostics 10 (9), 4116, 2020 | 27 | 2020 |
Mass spectrometry-based determination of Kallikrein-related peptidase 7 (KLK7) cleavage preferences and subsite dependency LM Silva, T Stoll, T Kryza, CR Stephens, ML Hastie, HF Irving-Rodgers, ... Scientific reports 7 (1), 6789, 2017 | 26 | 2017 |
Kallikrein‐related peptidase 4 induces cancer‐associated fibroblast features in prostate‐derived stromal cells T Kryza, LM Silva, N Bock, RA Fuhrman‐Luck, CR Stephens, J Gao, ... Molecular Oncology 11 (10), 1307-1329, 2017 | 24 | 2017 |
Integration of two in-depth quantitative proteomics approaches determines the kallikrein-related peptidase 7 (KLK7) degradome in ovarian cancer cell secretome LM Silva, T Kryza, T Stoll, C Hoogland, Y Dong, CR Stephens, ML Hastie, ... Molecular & Cellular Proteomics 18 (5), 818-836, 2019 | 22 | 2019 |
Substrate-biased activity-based probes identify proteases that cleave receptor CDCP1 T Kryza, T Khan, S Lovell, BS Harrington, J Yin, S Porazinski, M Pajic, ... Nature chemical biology 17 (7), 776-783, 2021 | 19 | 2021 |
A suite of activity-based probes to dissect the KLK activome in drug-resistant prostate cancer S Lovell, L Zhang, T Kryza, A Neodo, N Bock, E De Vita, ED Williams, ... Journal of the American Chemical Society 143 (23), 8911-8924, 2021 | 19 | 2021 |
Anti-CDCP1 immuno-conjugates for detection and inhibition of ovarian cancer BS Harrington, Y He, T Khan, S Puttick, PJ Conroy, T Kryza, T Cuda, ... Theranostics 10 (5), 2095, 2020 | 19 | 2020 |
Human kallikrein-related peptidase 12 stimulates endothelial cell migration by remodeling the fibronectin matrix T Kryza, C Parent, J Pardessus, A Petit, J Burlaud-Gaillard, P Reverdiau, ... Scientific reports 8 (1), 6331, 2018 | 19 | 2018 |
Pro-angiogenic effect of human kallikrein-related peptidase 12 (KLK12) in lung endothelial cells does not depend on kinin-mediated activation of B2 receptor T Kryza, G Lalmanach, M Lavergne, F Lecaille, P Reverdiau, Y Courty, ... Biological chemistry 394 (3), 385-391, 2013 | 18 | 2013 |
GelMA, click-chemistry gelatin and bioprinted polyethylene glycol-based hydrogels as 3D ex vivo drug testing platforms for patient-derived breast Cancer Organoids N Bock, F Forouz, L Hipwood, J Clegg, P Jeffery, M Gough, ... Pharmaceutics 15 (1), 261, 2023 | 17 | 2023 |