Conversion of stem cells to cancer stem cells: undercurrent of cancer initiation SM Afify, M Seno Cancers 11 (3), 345, 2019 | 183 | 2019 |
A novel model of liver cancer stem cells developed from induced pluripotent stem cells SM Afify, A Sanchez Calle, G Hassan, K Kumon, HM Nawara, MH Zahra, ... British Journal of Cancer 122 (9), 1378-1390, 2020 | 67 | 2020 |
Revisiting cancer stem cells as the origin of cancer-associated cells in the tumor microenvironment: a hypothetical view from the potential of iPSCs A Osman, SM Afify, G Hassan, X Fu, A Seno, M Seno Cancers 12 (4), 879, 2020 | 57 | 2020 |
Cancer-inducing niche: the force of chronic inflammation SM Afify, G Hassan, A Seno, M Seno British Journal of Cancer 127 (2), 193-201, 2022 | 46 | 2022 |
Paclitaxel-based chemotherapy targeting cancer stem cells from mono-to combination therapy HM Nawara, SM Afify, G Hassan, MH Zahra, A Seno, M Seno Biomedicines 9 (5), 500, 2021 | 46 | 2021 |
Targeting ovarian cancer cells overexpressing CD44 with immunoliposomes encapsulating glycosylated paclitaxel AC Khayrani, H Mahmud, AKK Oo, MH Zahra, M Oze, J Du, MJ Alam, ... International journal of molecular sciences 20 (5), 1042, 2019 | 37 | 2019 |
How can we turn the PI3K/AKT/mTOR pathway down? Insights into inhibition and treatment of cancer SM Afify, AKK Oo, G Hassan, A Seno, M Seno Expert Review of Anticancer Therapy 21 (6), 605-619, 2021 | 29 | 2021 |
Hematopoietic cells derived from cancer stem cells generated from mouse induced pluripotent stem cells G Hassan, SM Afify, N Nair, K Kumon, A Osman, J Du, H Mansour, ... Cancers 12 (1), 82, 2019 | 25 | 2019 |
Tumor-associated macrophages derived from cancer stem cells A Osman, M Oze, SM Afify, G Hassan, ELG Samah, HM Nawara, X Fu, ... Acta Histochemica 122 (8), 151628, 2020 | 21 | 2020 |
Signaling inhibitors accelerate the conversion of mouse iPS cells into cancer stem cells in the tumor microenvironment J Du, Y Xu, S Sasada, AKK Oo, G Hassan, H Mahmud, AC Khayrani, ... Scientific reports 10 (1), 9955, 2020 | 21 | 2020 |
Paclitaxel and sorafenib: The effective combination of suppressing the self-renewal of cancer stem cells HM Nawara, SM Afify, G Hassan, MH Zahra, MN Atallah, H Mansour, ... Cancers 12 (6), 1360, 2020 | 20 | 2020 |
Chronic exposure to FGF2 converts iPSCs into cancer stem cells with an enhanced integrin/focal adhesion/PI3K/AKT axis M Sheta, G Hassan, SM Afify, S Monzur, K Kumon, HAA Quora, M Farahat, ... Cancer Letters 521, 142-154, 2021 | 19 | 2021 |
Five fibrosis biomarkers together with serum ferritin level to diagnose liver fibrosis and cirrhosis SM Afify, A Tabll, HM Nawara, M El Kassas, A Elfert, M Seno, S El-Kousy Clin Lab 64 (10), 1685-1693, 2018 | 19 | 2018 |
Method to convert stem cells into cancer stem cells SM Afify, L Chen, T Yan, A Sanchez Calle, N Nair, C Murakami, MH Zahra, ... Methods and Protocols 2 (3), 71, 2019 | 17 | 2019 |
Isolation and characterization of cancer stem cells derived from human glioblastoma H Ishii, Y Mimura, MH Zahra, S Katayama, G Hassan, SM Afify, M Seno American Journal of Cancer Research 11 (2), 441, 2021 | 15 | 2021 |
Cancer stem cell initiation by tumor-derived extracellular vesicles SM Afify, G Hassan, T Yan, A Seno, M Seno Induced Pluripotent Stem Cells and Human Disease: Methods and Protocols, 399-407, 2021 | 14 | 2021 |
Cancer stem cell microenvironment models with biomaterial scaffolds in vitro G Hassan, SM Afify, S Kitano, A Seno, H Ishii, Y Shang, M Matsusaki, ... Processes 9 (1), 45, 2020 | 14 | 2020 |
The efficacy of PI3Kγ and EGFR inhibitors on the suppression of the characteristics of cancer stem cells Y Xu, SM Afify, J Du, B Liu, G Hassan, Q Wang, H Li, Y Liu, X Fu, Z Zhu, ... Scientific reports 12 (1), 347, 2022 | 13 | 2022 |
Metformin suppresses self‐renewal and stemness of cancer stem cell models derived from pluripotent stem cells MH Zahra, SM Afify, G Hassan, HM Nawara, K Kumon, A Seno, M Seno Cell biochemistry and function 39 (7), 896-907, 2021 | 13 | 2021 |
Different pancreatic cancer microenvironments convert iPSCs into cancer stem cells exhibiting distinct plasticity with altered gene expression of metabolic pathways G Hassan, T Ohara, SM Afify, K Kumon, MH Zahra, X Fu, M Al Kadi, ... Journal of Experimental & Clinical Cancer Research 41 (1), 29, 2022 | 12 | 2022 |