| NF-κB inhibition delays DNA damage–induced senescence and aging in mice JS Tilstra, AR Robinson, J Wang, SQ Gregg, CL Clauson, DP Reay, ... The Journal of clinical investigation 122 (7), 2601-2612, 2012 | 506 | 2012 |
| An aged immune system drives senescence and ageing of solid organs MJ Yousefzadeh, RR Flores, YI Zhu, ZC Schmiechen, RW Brooks, ... Nature 594 (7861), 100-105, 2021 | 501 | 2021 |
| Expression and regulation of metalloproteinases and their inhibitors in intervertebral disc aging and degeneration NV Vo, RA Hartman, T Yurube, LJ Jacobs, GA Sowa, JD Kang The Spine Journal 13 (3), 331-341, 2013 | 416 | 2013 |
| Molecular mechanisms of biological aging in intervertebral discs NV Vo, RA Hartman, PR Patil, MV Risbud, D Kletsas, JC Iatridis, ... Journal of orthopaedic research 34 (8), 1289-1306, 2016 | 393 | 2016 |
| Molecular basis of intervertebral disc degeneration and herniations: what are the important translational questions? T Kadow, G Sowa, N Vo, JD Kang Clinical Orthopaedics and Related Research® 473, 1903-1912, 2015 | 299 | 2015 |
| Inflammatory and catabolic signalling in intervertebral discs: the roles of NF-κB and MAP kinases K Wuertz, N Vo, D Kletsas, N Boos European Cells and Materials 23, 103-119; discussion 119, 2012 | 263 | 2012 |
| Mitochondrial‐derived reactive oxygen species (ROS) play a causal role in aging‐related intervertebral disc degeneration LA Nasto, AR Robinson, K Ngo, CL Clauson, Q Dong, C St. Croix, ... Journal of Orthopaedic Research 31 (7), 1150-1157, 2013 | 188 | 2013 |
| Human nucleus pulposus cells react to IL-6: independent actions and amplification of response to IL-1 and TNF-α RK Studer, N Vo, G Sowa, C Ondeck, J Kang Spine 36 (8), 593-599, 2011 | 183 | 2011 |
| Escherichia coli transcript cleavage factors GreA and GreB stimulate promoter escape and gene expression in vivo and in vitro. LM Hsu, NV Vo, MJ Chamberlin Proceedings of the National Academy of Sciences 92 (25), 11588-11592, 1995 | 171 | 1995 |
| p38 MAPK inhibition in nucleus pulposus cells: a potential target for treating intervertebral disc degeneration RK Studer, AM Aboka, LG Gilbertson, H Georgescu, G Sowa, N Vo, ... Spine 32 (25), 2827-2833, 2007 | 154 | 2007 |
| Systemic clearance of p16INK4a‐positive senescent cells mitigates age‐associated intervertebral disc degeneration P Patil, Q Dong, D Wang, J Chang, C Wiley, M Demaria, J Lee, J Kang, ... Aging cell 18 (3), e12927, 2019 | 143 | 2019 |
| Age-related declines in α-Klotho drive progenitor cell mitochondrial dysfunction and impaired muscle regeneration A Sahu, H Mamiya, SN Shinde, A Cheikhi, LL Winter, NV Vo, D Stolz, ... Nature communications 9 (1), 4859, 2018 | 139 | 2018 |
| Spine degeneration in a murine model of chronic human tobacco smokers D Wang, LA Nasto, P Roughley, AS Leme, AM Houghton, A Usas, ... Osteoarthritis and Cartilage 20 (8), 896-905, 2012 | 134 | 2012 |
| Injection of AAV2-BMP2 and AAV2-TIMP1 into the nucleus pulposus slows the course of intervertebral disc degeneration in an in vivo rabbit model SK Leckie, BP Bechara, RA Hartman, GA Sowa, BI Woods, JP Coelho, ... The Spine Journal 12 (1), 7-20, 2012 | 132 | 2012 |
| p38 MAPK inhibition modulates rabbit nucleus pulposus cell response to IL‐1 RK Studer, LG Gilbertson, H Georgescu, G Sowa, N Vo, JD Kang Journal of Orthopaedic Research 26 (7), 991-998, 2008 | 125 | 2008 |
| Mutagenic and inhibitory effects of ribavirin on hepatitis C virus RNA polymerase NV Vo, KC Young, MMC Lai Biochemistry 42 (35), 10462-10471, 2003 | 122 | 2003 |
| Accelerated aging of intervertebral discs in a mouse model of progeria N Vo, HY Seo, A Robinson, G Sowa, D Bentley, L Taylor, R Studer, ... Journal of Orthopaedic Research 28 (12), 1600-1607, 2010 | 118 | 2010 |
| Spontaneous DNA damage to the nuclear genome promotes senescence, redox imbalance and aging AR Robinson, MJ Yousefzadeh, TA Rozgaja, J Wang, X Li, JS Tilstra, ... Redox biology 17, 259-273, 2018 | 117 | 2018 |
| An overview of underlying causes and animal models for the study of age‐related degenerative disorders of the spine and synovial joints N Vo, LJ Niedernhofer, LA Nasto, L Jacobs, PD Robbins, J Kang, ... Journal of Orthopaedic Research 31 (6), 831-837, 2013 | 110 | 2013 |
| ISSLS prize winner: inhibition of NF-κB activity ameliorates age-associated disc degeneration in a mouse model of accelerated aging LA Nasto, HY Seo, AR Robinson, JS Tilstra, CL Clauson, GA Sowa, ... Spine 37 (21), 1819-1825, 2012 | 101 | 2012 |
