Protein–protein interactions: General trends in the relationship between binding affinity and interfacial buried surface area J Chen, N Sawyer, L Regan Protein Science 22 (4), 510-515, 2013 | 345 | 2013 |
Protein domain mimics as modulators of protein–protein interactions N Sawyer, AM Watkins, PS Arora Accounts of chemical research 50 (6), 1313-1322, 2017 | 100 | 2017 |
Bent into shape: Folded peptides to mimic protein structure and modulate protein function HI Merritt, N Sawyer, PS Arora Peptide Science 112 (1), e24145, 2020 | 53 | 2020 |
Hydrogen bond surrogate stabilization of β-hairpins N Sawyer, PS Arora ACS chemical biology 13 (8), 2027-2032, 2018 | 35 | 2018 |
All repeats are not equal: a module-based approach to guide repeat protein design N Sawyer, J Chen, L Regan Journal of molecular biology 425 (10), 1826-1838, 2013 | 35 | 2013 |
Designed Phosphoprotein Recognition in Escherichia coli N Sawyer, BM Gassaway, AD Haimovich, FJ Isaacs, J Rinehart, L Regan ACS chemical biology 9 (11), 2502-2507, 2014 | 26 | 2014 |
NextGen protein design N Sawyer, EB Speltz, L Regan Biochemical Society Transactions 41 (5), 1131-1136, 2013 | 26 | 2013 |
Covalent and noncovalent targeting of the Tcf4/β-catenin strand interface with β-hairpin mimics SL Blosser, N Sawyer, I Maksimovic, B Ghosh, PS Arora ACS chemical biology 16 (8), 1518-1525, 2021 | 18 | 2021 |
Macrocyclic β‐Sheets Stabilized by Hydrogen Bond Surrogates A Nazzaro, B Lu, N Sawyer, AM Watkins, PS Arora Angewandte Chemie 135 (41), e202303943, 2023 | 6 | 2023 |
Folding-Assisted Peptide Disulfide Formation and Dimerization CG Victorio, N Sawyer ACS Chemical Biology 18 (7), 1480-1486, 2023 | 4 | 2023 |
Using hydrogen bond surrogate technology to stabilize beta-hairpins N Sawyer, PS Arora Biophysical Journal 112 (3), 177a, 2017 | 3 | 2017 |
Protein goldendoodles: Designing new proteins N Sawyer, DM Williams, L Regan The Biochemist 36 (1), 28-33, 2014 | 3 | 2014 |
Anchor residues govern binding and folding of an intrinsically disordered domain HI Merritt, N Sawyer, AM Watkins, PS Arora ACS chemical biology 17 (10), 2723-2727, 2022 | 2 | 2022 |
Enhanced EphB2-Specific Peptide Inhibitors through Stabilization of Polyproline II Helical Structure JC Tennett, SR Epstein, N Sawyer ACS Chemical Biology, 2024 | 1 | 2024 |
Hydrogen bond surrogate beta-hairpins to inhibit protein-protein interactions N Sawyer, PS Arora Biophysical Journal 114 (3), 56a-57a, 2018 | 1 | 2018 |
Combining Design and Selection to Create Novel Protein–Peptide Interactions EB Speltz, N Sawyer, L Regan Methods in Enzymology 580, 203-222, 2016 | 1 | 2016 |
Structural Characterization of Disulfide-Linked p53-Derived Peptide Dimers MC DiGiorno, N Vithanage, CG Victorio, DF Kreitler, VK Outlaw, N Sawyer International Journal of Peptide Research and Therapeutics 30 (6), 68, 2024 | | 2024 |
Controlling Disulfide Formation and Dimerization to Constrain Alternate Peptide Conformations C Victorio, N Sawyer 2023 AIChE Annual Meeting, 2023 | | 2023 |
Modular Design and Selection of Phosphospecific Tetratricopeptide Repeat Affinity Proteins NA Sawyer Yale University, 2016 | | 2016 |
Engineering Novel Phosphopeptide Recognition Modules that Recognize Targets In Vitro and in E. coli N Sawyer, L Regan, B Gassaway, J Rinehart, A Haimovich, F Isaacs PROTEIN SCIENCE 23, 131-132, 2014 | | 2014 |