Therapeutic Potential of Spirooxindoles as Antiviral Agents N Ye, H Chen, EA Wold, PY Shi, J Zhou ACS Infectious Diseases 2 (6), 382-392, 2016 | 374 | 2016 |
Drug Discovery Targeting Bromodomain-Containing Protein 4 Z Liu, P Wang, H Chen, EA Wold, B Tian, AR Brasier, J Zhou Journal of Medicinal Chemistry 60 (11), 4533-4558, 2017 | 268 | 2017 |
Discovery and development of natural product oridonin-inspired anticancer agents Y Ding, C Ding, N Ye, Z Liu, EA Wold, H Chen, C Wild, Q Shen, J Zhou European Journal of Medicinal Chemistry 122, 102-117, 2016 | 163 | 2016 |
Allosteric Modulation of Class A GPCRs: Targets, Agents, and Emerging Concepts EA Wold, J Chen, KA Cunningham, J Zhou Journal of Medicinal Chemistry 62 (1), 88-127, 2018 | 141 | 2018 |
Therapeutic Potential of Oridonin and Its Analogs: From Anticancer and Antiinflammation to Neuroprotection J Xu, EA Wold, Y Ding, Q Shen, J Zhou Molecules 23 (2), 474, 2018 | 108 | 2018 |
BH4 domain of Bcl-2 as a novel target for cancer therapy Z Liu, C Wild, Y Ding, N Ye, H Chen, EA Wold, J Zhou Drug Discovery Today 21 (6), 989-996, 2016 | 65 | 2016 |
Discovery of Orally Bioavailable Chromone Derivatives as Potent and Selective BRD4 Inhibitors: Scaffolding Hopping, Optimization and Pharmacological Evaluation Z Liu, H Chen, P Wang, Y Li, EA Wold, PG Leonard, S Joseph, AR Brasier, ... Journal of Medicinal Chemistry 63 (10), 5242-5256, 2020 | 61 | 2020 |
Small Molecules Selectively Targeting Sigma-1 Receptor for the Treatment of Neurological Diseases N Ye, W Qin, S Tian, Q Xu, EA Wold, J Zhou, XC Zhen Journal of Medicinal Chemistry 63 (24), 15187-15217, 2020 | 59 | 2020 |
Targeting the 5-HT2C Receptor in Biological Context and the Current State of 5-HT2C Receptor Ligand Development. EA Wold, CT Wild, KA Cunningham, J Zhou Current Topics in Medicinal Chemistry 19, 1381-1398, 2019 | 49 | 2019 |
Regio-and Stereospecific Synthesis of Oridonin D-Ring Aziridinated Analogues for the Treatment of Triple-Negative Breast Cancer via Mediated Irreversible Covalent Warheads Y Ding, D Li, C Ding, P Wang, Z Liu, EA Wold, N Ye, H Chen, MA White, ... Journal of Medicinal Chemistry 61 (7), 2737-2752, 2018 | 33 | 2018 |
Orphan Receptor GPR88 as an Emerging Neurotherapeutic Target N Ye, B Li, Q Mao, EA Wold, S Tian, JA Allen, J Zhou ACS Chemical Neuroscience 10 (1), 190-200, 2019 | 31 | 2019 |
Design, Synthesis, and Characterization of 4-Undecylpiperidine-2-Carboxamides as Positive Allosteric Modulators of the Serotonin (5-HT) 5-HT2C Receptor CT Wild, JM Miszkiel, EA Wold, CA Soto, C Ding, RM Hartley, MA White, ... Journal of Medicinal Chemistry 62 (1), 288-305, 2018 | 31 | 2018 |
Small-Molecule Inhibitors Targeting the Canonical WNT Signaling Pathway for the Treatment of Cancer Z Liu, P Wang, EA Wold, Q Song, C Zhao, C Wang, J Zhou Journal of Medicinal Chemistry 64 (8), 4257-4288, 2021 | 29 | 2021 |
Discovery, X-ray Crystallography, and Anti-inflammatory Activity of Bromodomain-containing Protein 4 (BRD4) BD1 Inhibitors Targeting a Distinct New Binding Site Z Liu, Y Li, H Chen, H Lai, P Wang, S Wu, EA Wold, PG Leonard, ... Journal of Medicinal Chemistry 65 (3), 2388-2408, 2022 | 26 | 2022 |
GPCR Allosteric Modulators: Mechanistic Advantages and Therapeutic Applications EA Wold, J Zhou Current Topics in Medicinal Chemistry 18 (23), 2002-2006, 2019 | 26 | 2019 |
Inorganic arsenic–related changes in the stromal tumor microenvironment in a prostate cancer cell–conditioned media model JJ Shearer, EA Wold, CS Umbaugh, CF Lichti, CL Nilsson, ML Figueiredo Environmental Health Perspectives 124 (7), 1009, 2016 | 21 | 2016 |
Discovery of 4-Phenylpiperidine-2-Carboxamide Analogues as Serotonin 5-HT2C Receptor Positive Allosteric Modulators with Enhanced Drug-Like Properties EA Wold, EJ Garcia, CT Wild, JM Miszkiel, CA Soto, J Chen, K Pazdrak, ... Journal of Medicinal Chemistry 63 (14), 7529-7544, 2020 | 18 | 2020 |
Structure-Activity Relationship Studies on Bax Activator SMBA1 for the Treatment of ER-Positive and Triple-Negative Breast Cancer G Liu, T Yin, H Kim, C Ding, Z Yu, H Wang, H Chen, R Yan, EA Wold, ... European Journal of Medicinal Chemistry 178, 589-605, 2019 | 14 | 2019 |
Small-Molecule Inhibitors of Protein-Protein Interactions Z Liu, H Chen, EA Wold, J Zhou Reference Module in Chemistry, Molecular Sciences and Chemical Engineering …, 2017 | 13 | 2017 |
Applications of Bioorthogonal Chemistry in Tumor-Targeted Drug Discovery G Liu, EA Wold, J Zhou Current Topics in Medicinal Chemistry 19 (11), 892-897, 2019 | 12 | 2019 |