Activation of phospholipase Cγ by PI 3‐kinase‐induced PH domain‐mediated membrane targeting M Falasca, SK Logan, VP Lehto, G Baccante, MA Lemmon, ... The EMBO journal, 1998 | 743 | 1998 |
Pancreatic ductal adenocarcinoma: current and evolving therapies A Adamska, A Domenichini, M Falasca International journal of molecular sciences 18 (7), 1338, 2017 | 627 | 2017 |
Specificity and promiscuity in phosphoinositide binding by pleckstrin homology domains JM Kavran, DE Klein, A Lee, M Falasca, SJ Isakoff, EY Skolnik, ... Journal of Biological Chemistry 273 (46), 30497-30508, 1998 | 566 | 1998 |
A novel positive feedback loop mediated by the docking protein Gab1 and phosphatidylinositol 3-kinase in epidermal growth factor receptor signaling GA Rodrigues, M Falasca, Z Zhang, SH Ong, J Schlessinger Molecular and cellular biology, 2000 | 460 | 2000 |
ABC transporters in cancer stem cells: beyond chemoresistance RR Begicevic, M Falasca International journal of molecular sciences 18 (11), 2362, 2017 | 387 | 2017 |
Pyk2 regulates multiple signaling events crucial for macrophage morphology and migration M Okigaki, C Davis, M Falasca, S Harroch, DP Felsenfeld, MP Sheetz, ... Proceedings of the National Academy of Sciences 100 (19), 10740-10745, 2003 | 333 | 2003 |
The putative cannabinoid receptor GPR55 defines a novel autocrine loop in cancer cell proliferation R Piñeiro, T Maffucci, M Falasca Oncogene 30 (2), 142-152, 2011 | 279 | 2011 |
Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches JA Welsh, DCI Goberdhan, L O'Driscoll, EI Buzas, C Blenkiron, ... Journal of extracellular vesicles 13 (2), e12404, 2024 | 250 | 2024 |
Class II phosphoinositide 3-kinase defines a novel signaling pathway in cell migration T Maffucci, FT Cooke, FM Foster, CJ Traer, MJ Fry, M Falasca The Journal of cell biology 169 (5), 789-799, 2005 | 225 | 2005 |
PI3K class II α controls spatially restricted endosomal PtdIns3P and Rab11 activation to promote primary cilium function I Franco, F Gulluni, CC Campa, C Costa, JP Margaria, E Ciraolo, ... Developmental cell 28 (6), 647-658, 2014 | 209 | 2014 |
The role of phosphoinositide 3-kinase C2α in insulin signaling M Falasca, WE Hughes, V Dominguez, G Sala, F Fostira, MQ Fang, ... Journal of Biological Chemistry 282 (38), 28226-28236, 2007 | 207 | 2007 |
Large-scale plasma analysis revealed new mechanisms and molecules associated with the host response to SARS-CoV-2 E Barberis, S Timo, E Amede, VV Vanella, C Puricelli, G Cappellano, ... International journal of molecular sciences 21 (22), 8623, 2020 | 204 | 2020 |
Insulin induces phosphatidylinositol‐3‐phosphate formation through TC10 activation T Maffucci, A Brancaccio, E Piccolo, RC Stein, M Falasca The EMBO journal, 2003 | 199 | 2003 |
Regulatory recruitment of signalling molecules to the cell membrane by pleckstrinhomology domains MA Lemmon, M Falasca, J Schlessinger, K Ferguson Trends in Cell Biology 7 (6), 237-242, 1997 | 193 | 1997 |
Regulation and cellular functions of class II phosphoinositide 3-kinases M Falasca, T Maffucci Biochemical Journal 443 (3), 587-601, 2012 | 184 | 2012 |
Phospholipase Cγ1 is required for metastasis development and progression G Sala, F Dituri, C Raimondi, S Previdi, T Maffucci, M Mazzoletti, C Rossi, ... Cancer research 68 (24), 10187-10196, 2008 | 178 | 2008 |
PI3K-C2γ is a Rab5 effector selectively controlling endosomal Akt2 activation downstream of insulin signalling L Braccini, E Ciraolo, CC Campa, A Perino, DL Longo, G Tibolla, ... Nature communications 6 (1), 7400, 2015 | 174 | 2015 |
Inhibition of the phosphatidylinositol 3-kinase/Akt pathway by inositol pentakisphosphate results in antiangiogenic and antitumor effects T Maffucci, E Piccolo, A Cumashi, M Iezzi, AM Riley, A Saiardi, ... Cancer Research 65 (18), 8339-8349, 2005 | 170 | 2005 |
Targeting PDK1 in cancer C Raimondi, M Falasca Current medicinal chemistry 18 (18), 2763-2769, 2011 | 169 | 2011 |
Circulating exosomes are strongly involved in SARS-CoV-2 infection E Barberis, VV Vanella, M Falasca, V Caneapero, G Cappellano, ... Frontiers in molecular biosciences 8, 632290, 2021 | 167 | 2021 |